ProHealth me-cfs Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help

|
|

Trending News

The END ME/CFS Project

The CFS/ME Brain Is Inflamed

SURVEY: Cognitive Impairment

Disability Claims and Social Media

“End ME/CFS” Mega Chronic Fatigue Syndrome Project Begins

Serum cytokines in patients with moderate and severe Chronic Fatigue Syndrome/Myalgic Encephalomyeli...

Adverse events and deterioration reported by participants in the PACE trial of therapies for chronic...

Discerning primary and secondary factors responsible for clinical fatigue in multisystem diseases

Dr. Peter Rowe – Is The Physical Examination Normal in CFS? Part 3

Fight the Power

 
Print Page
Email Article

Omega-3 fatty acid supplementation decreases liver fat content in Polycystic Ovarian Syndrome: A randomised controlled trial employing proton magnetic resonance spectroscopy – Source: Journal of Clinical Endocrinology and Metabolism, Jul 21, 2009

  [ 35 votes ]   [ Discuss This Article ]
By Andrea J Cussons, et al. • www.ProHealth.com • September 7, 2009


[Note: Polycystic ovary syndrome affects about 5% of reproductive age females. It is the most common hormonal problem affecting this population and has been associated with elevated risk of liver damage owing to fat accumulation in the liver, diabetes 2, and cardiovascular disease.]

Context: There is an association between non-alcoholic fatty liver disease (NAFLD) and the polycystic ovary syndrome (PCOS).

Marine derived omega-3 fatty acids [e.g., fish, krill oil] have favorable effects on cardiovascular risk, and could reduce liver fat in NAFLD.

Objective: The primary aim of this study was to examine the effects of omega-3 fatty acids on liver fat in PCOS. The secondary aim was to assess their effects on traditional cardiovascular risk factors.

Design: Randomized, cross-over study.

Setting: Tertiary cardiovascular research centre.

Subjects: 25 women with PCOS (mean age 32.7 yr, mean body mass index 34.8 kg/m(2)).

Intervention: Comparison of 4g/day of omega-3 fatty acids with placebo over 8 weeks.

Main outcome measures:
The primary outcome measure was hepatic fat content quantified using proton magnetic resonance spectroscopy. Secondary outcome measures included fasting lipids and blood pressure.

Results:

• Omega-3 fatty acids significantly decreased liver fat content compared with placebo (10.2(1.1) v 8.4(0.9)%, p=0.022).

• There was also a reduction in triglycerides (1.19(1.03-1.47) v 1.02(0.93-1.18)mmol/L, p=0.002), systolic blood pressure (124.1(12.1) v 122.3(14.5)mmHg, p=0.018), and diastolic blood pressure (73.2(8.4) v 69.7(8.3)mmHg, p=0.005) with omega-3 fatty acids compared with placebo.

• Omega-3 fatty acids particularly decreased hepatic fat in women with hepatic steatosis, defined as percentage liver fat greater than 5%, (18.2(11.1) v 14.8(9.3)%, p=0.03).

Conclusions: Omega-3 fatty acid supplementation has a beneficial effect on liver fat content and other cardiovascular risk factors in women with PCOS, including those with hepatic steatosis. Whether this translates into a reduction in cardiometabolic events warrants further study.

Source: Journal of Clinical Endocrinology and Metabolism, Jul 21, 2009. PMID: 19622617, by Cussons AJ, Watts GF, Mori TA, Stuckey BG. University of Western Australia School of Medicine & Pharmacology, and Department of Endocrinology and Diabetes, Royal Perth Hospital, Perth, Western Australia; Keogh Institute for Medical Research, Nedlands, Western Australia; Department of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Nedlands, Western Australia. [E-mail: acussons@meddent.uwa.edu.au]




Please Discuss This Article:   Post a Comment 



[ Be the first to comment on this article ]




 
Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Our FREE
Newsletter
Subscribe Now!
Receive up-to-date ME/CFS & Fibromyalgia treatment and research news
 Privacy Guaranteed  |  View Archives

Save on Vitamins and Supplements

Featured Products

MitoQ® MitoQ®
Powerful Antioxidant Support to Mitochondria
Hydroxocobalamin Extreme™ Hydroxocobalamin Extreme™
The B-12 your brain needs for detox & sharpness
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils

Natural Remedies

The Big Blue Fish that Helps Chase the Blues Away The Big Blue Fish that Helps Chase the Blues Away
VIDEO: Healthy Eating and Fibromyalgia VIDEO: Healthy Eating and Fibromyalgia
Repair Damaged Mitochondria and Reduce Fatigue Up to 45% Repair Damaged Mitochondria and Reduce Fatigue Up to 45%
Protect Against Sun-Induced Skin Aging From The Inside Out Protect Against Sun-Induced Skin Aging From The Inside Out
More Weight Loss than Any Other Discovery in Supplement History More Weight Loss than Any Other Discovery in Supplement History

FIBROMYALGIA RESOURCES
What is Fibromyalgia?
Fibromyalgia 101
Fibromyalgia Symptoms
Fibromyalgia Treatments
| CFS RESOURCES
What is CFS?
ME/CFS 101
ME/CFS Symptoms
ME/CFS Treatments
| FORUMS
Fibromyalgia
ME/CFS
ADVANCED MEDICAL LABS
WHOLESALE  |  AFFILIATES
GUARANTEE
CONTACT US
PRIVACY
RSS
SITE MAP
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing