ProHealth me-cfs Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

The New Me

Creating Intimacy Through Mindful Touch When You Live with Chronic Illness

VIDEO: How does your brain respond to pain?

4 Ways to Give Back When You’re Chronically Ill

Millions Missing Day of Protest Draws Attention to Plight of ME/CFS Patients All Over the Globe

10 Fibro-Friendly Foods with a Bonus: Beautiful Skin

An Illness Denied for Decades Is Exposed - Lighting Up a Hidden World: CFS and ME

Studies Show that Magnesium L-threonate Improves Brain Plasticity, Leading to Direct and Significant...

Pumpkin Pie Turmeric Breakfast Smoothie - Vegan + Gluten-Free

SURVEY RESULTS: Weight Management & Chronic Illness

Print Page
Email Article

Omega-3 fatty acid supplementation decreases liver fat content in Polycystic Ovarian Syndrome: A randomised controlled trial employing proton magnetic resonance spectroscopy – Source: Journal of Clinical Endocrinology and Metabolism, Jul 21, 2009

  [ 35 votes ]   [ Discuss This Article ]
By Andrea J Cussons, et al. • • September 7, 2009

[Note: Polycystic ovary syndrome affects about 5% of reproductive age females. It is the most common hormonal problem affecting this population and has been associated with elevated risk of liver damage owing to fat accumulation in the liver, diabetes 2, and cardiovascular disease.]

Context: There is an association between non-alcoholic fatty liver disease (NAFLD) and the polycystic ovary syndrome (PCOS).

Marine derived omega-3 fatty acids [e.g., fish, krill oil] have favorable effects on cardiovascular risk, and could reduce liver fat in NAFLD.

Objective: The primary aim of this study was to examine the effects of omega-3 fatty acids on liver fat in PCOS. The secondary aim was to assess their effects on traditional cardiovascular risk factors.

Design: Randomized, cross-over study.

Setting: Tertiary cardiovascular research centre.

Subjects: 25 women with PCOS (mean age 32.7 yr, mean body mass index 34.8 kg/m(2)).

Intervention: Comparison of 4g/day of omega-3 fatty acids with placebo over 8 weeks.

Main outcome measures: The primary outcome measure was hepatic fat content quantified using proton magnetic resonance spectroscopy. Secondary outcome measures included fasting lipids and blood pressure.


• Omega-3 fatty acids significantly decreased liver fat content compared with placebo (10.2(1.1) v 8.4(0.9)%, p=0.022).

• There was also a reduction in triglycerides (1.19(1.03-1.47) v 1.02(0.93-1.18)mmol/L, p=0.002), systolic blood pressure (124.1(12.1) v 122.3(14.5)mmHg, p=0.018), and diastolic blood pressure (73.2(8.4) v 69.7(8.3)mmHg, p=0.005) with omega-3 fatty acids compared with placebo.

• Omega-3 fatty acids particularly decreased hepatic fat in women with hepatic steatosis, defined as percentage liver fat greater than 5%, (18.2(11.1) v 14.8(9.3)%, p=0.03).

Conclusions: Omega-3 fatty acid supplementation has a beneficial effect on liver fat content and other cardiovascular risk factors in women with PCOS, including those with hepatic steatosis. Whether this translates into a reduction in cardiometabolic events warrants further study.

Source: Journal of Clinical Endocrinology and Metabolism, Jul 21, 2009. PMID: 19622617, by Cussons AJ, Watts GF, Mori TA, Stuckey BG. University of Western Australia School of Medicine & Pharmacology, and Department of Endocrinology and Diabetes, Royal Perth Hospital, Perth, Western Australia; Keogh Institute for Medical Research, Nedlands, Western Australia; Department of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Nedlands, Western Australia. [E-mail:]

Post a Comment

Featured Products From the ProHealth Store
MitoQ® Ultra EPA  - Fish Oil Energy NADH™ 12.5mg

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products

Article Comments

Be the first to comment on this article!

Post a Comment

Natural Pain Relief Supplements

Featured Products

Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
B-12 Extreme™ B-12 Extreme™
The Most Potent Vitamin B-12 on Earth

Natural Remedies

Itching to Find Dry Skin Relief? Itching to Find Dry Skin Relief?
Coping When Colds or Flu Catch Up with You Coping When Colds or Flu Catch Up with You
Probiotic Mint Promotes Healthy Gums & Teeth, Freshens Breath and Whitens Teeth Probiotic Mint Promotes Healthy Gums & Teeth, Freshens Breath and Whitens Teeth
Help for Soreness and Swelling: What Do Silkworms Have to Do With It? Help for Soreness and Swelling: What Do Silkworms Have to Do With It?
Reversing Neurodegeneration with a New Magnesium Compound Reversing Neurodegeneration with a New Magnesium Compound

ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
Credit Card Processing
Be the first to know about new products, special discounts and the latest health news. *New subscribers only

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2016 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map