ProHealth me-cfs Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help

|
|

Trending News

Happiness, Gratitude and Appreciation

New clinical research program to combat chronic pain and chronic fatigue syndrome

It’s Still a Wonderful Life

Lack of Knowledgeable Healthcare Access for Patients with Neuro-endocrine-immune Diseases

Survey Data on Name Change for ME/CFS Analyzed for Publication

Assessment of activity limitations and participation restrictions with persons with chronic fatigue ...

Help the National ME/FM Action Network win $5000!

Shake That *^#&! ing Stigma – The “Shake the CFS Stigma Challenge” Begins

Now Is the Time for a National PR Campaign for ME/CFS!

US Disabled Hold Protests at Bethesda

 
Print Page
Email Article

Omega-3 fatty acid supplementation decreases liver fat content in Polycystic Ovarian Syndrome: A randomised controlled trial employing proton magnetic resonance spectroscopy – Source: Journal of Clinical Endocrinology and Metabolism, Jul 21, 2009

  [ 35 votes ]   [ Discuss This Article ]
By Andrea J Cussons, et al. • www.ProHealth.com • September 7, 2009


[Note: Polycystic ovary syndrome affects about 5% of reproductive age females. It is the most common hormonal problem affecting this population and has been associated with elevated risk of liver damage owing to fat accumulation in the liver, diabetes 2, and cardiovascular disease.]

Context: There is an association between non-alcoholic fatty liver disease (NAFLD) and the polycystic ovary syndrome (PCOS).

Marine derived omega-3 fatty acids [e.g., fish, krill oil] have favorable effects on cardiovascular risk, and could reduce liver fat in NAFLD.

Objective: The primary aim of this study was to examine the effects of omega-3 fatty acids on liver fat in PCOS. The secondary aim was to assess their effects on traditional cardiovascular risk factors.

Design: Randomized, cross-over study.

Setting: Tertiary cardiovascular research centre.

Subjects: 25 women with PCOS (mean age 32.7 yr, mean body mass index 34.8 kg/m(2)).

Intervention: Comparison of 4g/day of omega-3 fatty acids with placebo over 8 weeks.

Main outcome measures:
The primary outcome measure was hepatic fat content quantified using proton magnetic resonance spectroscopy. Secondary outcome measures included fasting lipids and blood pressure.

Results:

• Omega-3 fatty acids significantly decreased liver fat content compared with placebo (10.2(1.1) v 8.4(0.9)%, p=0.022).

• There was also a reduction in triglycerides (1.19(1.03-1.47) v 1.02(0.93-1.18)mmol/L, p=0.002), systolic blood pressure (124.1(12.1) v 122.3(14.5)mmHg, p=0.018), and diastolic blood pressure (73.2(8.4) v 69.7(8.3)mmHg, p=0.005) with omega-3 fatty acids compared with placebo.

• Omega-3 fatty acids particularly decreased hepatic fat in women with hepatic steatosis, defined as percentage liver fat greater than 5%, (18.2(11.1) v 14.8(9.3)%, p=0.03).

Conclusions: Omega-3 fatty acid supplementation has a beneficial effect on liver fat content and other cardiovascular risk factors in women with PCOS, including those with hepatic steatosis. Whether this translates into a reduction in cardiometabolic events warrants further study.

Source: Journal of Clinical Endocrinology and Metabolism, Jul 21, 2009. PMID: 19622617, by Cussons AJ, Watts GF, Mori TA, Stuckey BG. University of Western Australia School of Medicine & Pharmacology, and Department of Endocrinology and Diabetes, Royal Perth Hospital, Perth, Western Australia; Keogh Institute for Medical Research, Nedlands, Western Australia; Department of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Nedlands, Western Australia. [E-mail: acussons@meddent.uwa.edu.au]




Please Discuss This Article:   Post a Comment 



[ Be the first to comment on this article ]




 
Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Our FREE
Newsletter
Subscribe Now!
Receive up-to-date ME/CFS & Fibromyalgia treatment and research news
 Privacy Guaranteed  |  View Archives

Save on Nutritional Supplement Orders

Featured Products

B-12 Extreme™ B-12 Extreme™
The Most Potent Vitamin B-12 on Earth
Hydroxocobalamin Extreme™ Hydroxocobalamin Extreme™
The B-12 your brain needs for detox & sharpness
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils

Natural Remedies

Irritable Bowel Syndrome: Unlocking the Secrets of Peppermint, Acacia and Fennel Irritable Bowel Syndrome: Unlocking the Secrets of Peppermint, Acacia and Fennel
Broad Spectrum Protection Against Brain Aging Broad Spectrum Protection Against Brain Aging
Sunshine Vitamin Has D-lightful Health Benefits Sunshine Vitamin Has D-lightful Health Benefits
Shoo Pain, Don't Bother Me - Top 10 Nutrients to Take Back Your Life Shoo Pain, Don't Bother Me - Top 10 Nutrients to Take Back Your Life
Ubiquinol - A More Advanced Form of the Energy Producing Nutrient CoQ-10 Ubiquinol - A More Advanced Form of the Energy Producing Nutrient CoQ-10

FIBROMYALGIA RESOURCES
What is Fibromyalgia?
Fibromyalgia Diagnosis
Fibromyalgia Symptoms
Fibromyalgia Treatments
| CFS RESOURCES
What is CFS?
ME/CFS Diagnosis
ME/CFS Symptoms
ME/CFS Treatments
| FORUMS
Fibromyalgia
ME/CFS
ADVANCED MEDICAL LABS
WHOLESALE  |  AFFILIATES
GUARANTEE  |  PRIVACY
CONTACT US
LIBRARY
RSS
SITE MAP
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing