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Fibromyalgia and Celiac Disease: Media Hype or an Emerging Problem?

  [ 10 votes ]   [ 1 Comment ] • September 29, 2013

Editor's comment: Celiac disease (spelled coeliac disease in some countries) is an autoimmune disease in which the body's immune system attacks tissues in the small intestine.  These attacks are triggered by the ingestion of foods containing gluten (i.e., wheat, barley and rye).   

Fibromyalgia and coeliac disease: a media hype or an emerging clinical problem?

By F. Tovoli, et al.


OBJECTIVES: Fibromyalgia (FM) association with autoimmune diseases has been widely reported in literature. Coeliac disease (CD) is a small intestine immune-mediated disorder triggered by gluten ingestion in genetically predisposed patients. In recent years, the Internet and the non-medical press have reported a correlation between gluten-related disorders and fibromyalgia-like symptoms. The aim of our study was to verify a possible association between FM and CD, by assessing the prevalence of CD in a cohort of FM patients and vice versa.

METHODS: 90 consecutive subjects from our Rheumatologic outpatient clinic who had been diagnosed with FM were serologically tested for CD and positive patients underwent esophagogastroduodenoscopy to obtain duodenal biopsies. A second group of 114 consecutive subjects from our Coeliac Disease outpatient clinic were investigated for the presence of FM-like symptoms through a questionnaire. Patients reporting chronic widespread pain were addressed to a rheumatologist for further evaluation.

RESULTS: The overall prevalence of CD in our FM patients was identical to that expected in general population (around 1%). In our CD group 17 patients (14.9%) reported chronic widespread pain at the questionnaire and 13 (11.4%) satisfied ACR 1990 criteria for FM. Their symptoms had not been modified by GFD.

CONCLUSIONS: A serological screening for CD is not recommended in FM patients but rather a case-finding strategy should be performed. At the same time, proposals of GFD in FM patients, in absence of a well-established diagnosis of CD, should be rigorously avoided.

Source: Clinical and Experimental Rheumatology, September 9, 2013. By F. Tovoli, L. Giampaolo, G. Caio, M. Monti, M. Piscaglia, M. Frisoni, L. Bolondi and U. Volta. Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy.

Please Discuss This Article:   Post a Comment 

Posted by: dancer4109
Sep 30, 2013
I completely disagree with what is said here.. I was diagnosed with fibro myalgia 2 years ago and I was in so much pain it was unbearable, and I was only 19 at the time and I used to be athletic, I had tendinitis in almost every place possible, back pain that limited me from so much, nausea every single day and NOTHING worked the doctors just kept saying it was fibro myalgia and gave me more meds.. finally my boyfriend suggested I go gluten free and i did, eventually 100% and guess what a year later ALL my pains and nausea are gone! And I'm off all the meds Dr's had me on.. moral of the story people with fibro myalgia should be tested for celiac or go on a GF diet bwcause if I didn't I wouldnot be happy and living life again
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