we have a pretty active Arthritis Board.
I have arthritic knees and have gotten relief with taking MSM powder in higher doses every day and have been doing this for about 9 months. It has helped me.
Also I use homeopathic gels on my knees and I get relief there too. I like B&T products and the deep muscle trauma gel works best.
I don't know anything about the pearl stuff you mention, but do put this on the Arthritis Board and maybe someone over there knows about it.