ProHealth fibromyalgia Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Blood Test for Fibromyalgia: FM/a® Test is Real

The Big Hurt: Second Major Fibromyalgia Drug in a Year Fails

New Device Treats Widespread Fibromyalgia and Lyme-Related Pain

An open letter to Eli Lilly and all patients affected by Cymbalta's withdrawal symptoms

3 Things that Give Me Back More Energy Than They Take

12 bloggers share their best tips for reducing fibromyalgia symptoms

VIDEO: Fibromyalgia Pain Relief Stretching Program: Gentle but Effective

Savor the Summer

Are you “feeling” your feelings? Fibromyalgia and PTSD do not have to be a life sentence.

An Immune Disease? Low Dose Naltrexone (LDN) Fibromyalgia Study Suggests FM Has Inflammatory Side

 
Print Page
Email Article

Ischemic hypersensitivity in irritable bowel syndrome patients – Source: Pain Medicine, Nov 2010

  [ 7 votes ]   [ Discuss This Article ]
By Q Zhou, et al. • www.ProHealth.com • November 11, 2010


Objective: Mixed evidence exists regarding whether irritable bowel syndrome (IBS) patients show increased somatic pain perception compared with controls. The current study used a deep, tonic somatic pain stimulus (ischemic pain) to evaluate somatic hypersensitivity in IBS patients. [This is deep pain associated with decreased blood flow owing to obstruction or constriction.]

Methods: A total of 27 diarrhea-predominant and 15 constipation-predominant IBS patients, and 29 controls participated in the study. The modified submaximal effort tourniquet procedure was performed to induce ischemic arm pain, and the time required to reach pain threshold and pain tolerance were recorded in seconds. All subjects completed the Functional Bowel Disease Severity Index (FBDSI) scale as well as several psychosocial instruments. Group differences for threshold and tolerance were determined using a series of one-way ANOVA tests followed by Tukey comparisons.

Results: IBS patients had a shorter time to ischemic threshold (F = 34.606, P < 0.001) and tolerance (F =  38.656, P < 0.001) compared with controls; however, the groups did not differ on ratings of pain at the time of tolerance. IBS patients had a higher rating on the FBDSI scale compared with controls (P <  0.001), and ischemic pain threshold was negatively correlated with the FBDSI score.

Conclusions:

The results of this study suggest that a widespread alteration in central pain processing in IBS patients may be present as they display hypersensitivity to ischemic arm pain, and ischemic pain threshold was associated with clinical symptoms.

These findings could reflect a dysfunction in inhibitory pain systems in IBS patients, as ischemic (deep) pain may be under tonic inhibitory control. [Tonic control refers to nerve impulses that maintain tone or level of activity in muscles or other ‘effector’ organs, as in the GI tract.]

Source: Pain Medicine, Nov 2010;11(11):1619-27. PMID: 21029350, by Zhou Q, Fillingim RB, Riley JL, Verne GN. Department of Medicine, The Ohio State University, Columbus, Ohio; College of Dentistry, University of Florida, Gainesville, Florida; North Florida/South Georgia Veteran Health System, Gainesville, Florida; Research Service, Cincinnati VAMC, Cincinnati, Ohio, USA.





Post a Comment

Featured Products From the ProHealth Store
B-12 Extreme™ FibroSleep™ Energy NADH™ 12.5mg

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
NAD+ Ignite with Niagen

Featured Products

Fibro Freedom™ Fibro Freedom™
Soothes, Strengthens & Revitalizes
Hydroxocobalamin Extreme™ Hydroxocobalamin Extreme™
The B-12 Your Brain Needs for Detox & Sharpness
Guaifenesin FA™ Guaifenesin FA™
Helps the Body Eliminate Excess Calcium and Phosphates
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
B-12 Extreme™ B-12 Extreme™
The Most Potent Vitamin B-12 on Earth

Natural Remedies

The Genetic Mutation That May Compromise Your Health - And What to Do About It The Genetic Mutation That May Compromise Your Health - And What to Do About It
How I Found My Long-Lost Energy How I Found My Long-Lost Energy
Break Free From Fibromyalgia Break Free From Fibromyalgia
Everything You Always Wanted to Know About Sleep But Were Too Tired to Ask Everything You Always Wanted to Know About Sleep But Were Too Tired to Ask
Natural Relief for Soreness, Pain and Swelling - Putting Out the Fire Natural Relief for Soreness, Pain and Swelling - Putting Out the Fire

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map