GI flora transplantation’s healing promise for IBS, perhaps ME/CFS, even depression   (22 votes) ProHealth.com • November 13, 2012 Tweet previous article next article Article: Fecal microbiota transplantation: past, present and future - Source: Current Opinion in Gastroenterology, Oct 4, 2012 By Olga C Aroniadis, MD, Lawrence J Brandt, MD [Note: Drs. Aroniadis and Brandt specialize in the study of fecal transplantion at Montefiore Medical Center. They review emerging science demonstrating that a healthy balance of intestinal flora is the foundation of cellular immunity and energy metabolism; its disruption plays a role in many disorders including IBS and ME/CFS (per Drs. Peterson, Cheney, Myhill, de Meirleir, Enlander, etc.); and plan controlled studies of microbiota transplantation in hopes of opening new horizons in healing.] Abstract: Purpose of review: Fecal microbiota transplantation (FMT) re-establishes a balanced intestinal flora with resultant cure of recurrent Clostridium difficile infection (RCDI). FMT has also been used to treat other gastrointestinal (GI) diseases including: • Inflammatory bowel disease (IBD), • Irritable bowel syndrome (IBS), • Chronic constipation • And a variety of non-GI disorders. The purpose of this review is to discuss the intestinal microbiota and FMT treatment of GI and non-GI diseases. Recent findings: It is known that an imbalanced intestinal microbiota predisposes to CDI, IBD and IBS. The complex role of intestinal microbiota to maintain health, however, is a newer concept that is being increasingly studied. The microbiome plays an important role in cellular immunity and energy metabolism and has been implicated in the pathogenesis of: • Non-GI autoimmune diseases, • Chronic fatigue syndrome [ME/CFS], • Obesity, • And even some neuropsychiatric disorders. Summary: FMT is a highly effective cure for RCDI, but increased knowledge of the intestinal microbiota in health maintenance, as well as controlled trials of FMT in a wide range of disorders are needed before FMT can be accepted and applied clinically. Source: Current Opinion in Gastroenterology, Oct 4, 2012. PMID:23041678, by Aroniadis OC, Brandt LJ. Division of Gastroenterology, Montefiore Medical Center, Bronx, New York, USA. [Lbrandt@montefiore.org]

previous article   Rating 3.1 (22 votes) next article Tweet

RELATED PRODUCT CATEGORIES

ProHealth offers a wide range of nutritional supplements for optimal health.* *These products are not intended to diagnose, treat, cure, or prevent any disease. Detoxification Inflammation Probiotics

DISCUSS THIS ARTICLE   (0 existing comments)
[ Be the first to comment on this article ]