ProHealth fibromyalgia Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help

|
|
|

Trending News

New Restrictions on Painkillers: Tramadol and Hydrocodone

Small Fiber Neuropathy Fibromyalgia Study Raises Questions

A Fibromyalgia Tale of Two Sisters

Is Venlafaxine Effective for Treating Fibromyalgia?

SURVEY: Cognitive Impairment

The Past, Present and Future of Chronic Pain Treatment

Magnesium: Widespread Deficiency with Deadly Consequences

Can Online Cognitive Behavioral Therapy Help Fibromyalgia?

Disability Claims and Social Media

Increased Sensitivity in Fibromyalgia Not Due to Hypervigilance

 
Print Page
Email Article

MSG May Worsen Fibromyalgia Symptoms

  [ 2 votes ]   [ Discuss This Article ]
www.ProHealth.com • January 11, 2013


Article:

The effect of dietary glutamate on fibromyalgia and irritable bowel symptoms
– Source:  Clinical and Experimental Rheumatology, November – December 2012

By K. Holton, et al.

Abstract:

Objectives: To examine the effects of a challenge with monosodium glutamate (MSG) as compared to placebo on the symptoms of fibromyalgia (FM), in participants who initially experienced >30% remission of symptoms on an excitotoxin elimination diet.

Methods: Fifty-seven FM patients who also had irritable bowel syndrome (IBS) were placed on a 4-week diet that excluded dietary additive excitotoxins including MSG and aspartame. Thirty-seven people completed the diet and 84% of those reported that >30% of their symptoms resolved, thus making them eligible to proceed to challenges.

Subjects who improved on the diet were then randomised to a 2-week double-blind placebo-controlled crossover challenge with MSG or placebo for 3 consecutive days each week. The primary outcome measure was total symptom score. Secondary outcome measures included visual analogue pain scales (VAS for FM and IBS), an IBS Quality of Life Questionnaire (IBS QOL) and the Fibromyalgia Impact Questionnaire-Revised (FIQR). Repeated measures ANOVA was used to analyse crossover challenge results.

Results: The MSG challenge, as compared to placebo, resulted in a significant return of symptoms (total symptom score, p<0.02);

  • a worsening of fibromyalgia severity as determined by the FIQR (p<0.03);

  • decreased quality of life in regards to IBS symptoms (IBS QOL, p<0.05);

  • and a non-significant trend toward worsening FM pain based on visual analogue scale (VAS, p<0.07).

Conclusions: These findings suggest that dietary glutamate may be contributing to FM symptoms in some patients. Future research on the role of dietary excitotoxins in FM is warranted.


Source:  Clinical and Experimental Rheumatology, November – December 2012. By K. Holton, D. Taren, C. Thomson, R. Bennett, K. Jones. Departments of Orthopaedics and Rehabilitation, Oregon Health & Science University, Portland, OR, USA. E-mail: holtonk@ohsu.edu




Please Discuss This Article:   Post a Comment 



[ Be the first to comment on this article ]




 
Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Our FREE
Newsletter
Subscribe Now!
Receive up-to-date ME/CFS & Fibromyalgia treatment and research news
 Privacy Guaranteed  |  View Archives

Save on Vitamins and Supplements

Featured Products

Hydroxocobalamin Extreme™ Hydroxocobalamin Extreme™
The B-12 your brain needs for detox & sharpness
FibroSleep™ by ProHealth FibroSleep™ by ProHealth
The All-in-One Natural Sleep Aid
Guaifenesin FA™ Guaifenesin FA™
Natural Expectorant Relieves Chest Congestion
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Fibro Freedom™ Fibro Freedom™
Soothes, strengthens & revitalizes

Natural Remedies

Magnesium + Malic Acid: One-Two Punch for Pain & Fatigue Magnesium + Malic Acid: One-Two Punch for Pain & Fatigue
More Weight Loss than Any Other Discovery in Supplement History More Weight Loss than Any Other Discovery in Supplement History
Front Line Defense Against Colds & Flu - Support for Healthy Immune System Balance Front Line Defense Against Colds & Flu - Support for Healthy Immune System Balance
IBS, Crohn’s Disease, Colitis, and Other Digestive Disorders IBS, Crohn’s Disease, Colitis, and Other Digestive Disorders
"It's Not Easy Being Green" - But It Is Healthy

FIBROMYALGIA RESOURCES
What is Fibromyalgia?
Fibromyalgia 101
Fibromyalgia Symptoms
Fibromyalgia Treatments
| CFS RESOURCES
What is CFS?
ME/CFS 101
ME/CFS Symptoms
ME/CFS Treatments
| FORUMS
Fibromyalgia
ME/CFS
ADVANCED MEDICAL LABS
WHOLESALE  |  AFFILIATES
GUARANTEE
CONTACT US
PRIVACY
RSS
SITE MAP
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing