ProHealth fibromyalgia Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help

|
|
|

Trending News

Drug Combo in Pridgen Antiviral Fibromyalgia Trial Identified – Some Results Available

7 Fibromyalgia Seasonal Stress Strategies

Novel Fibromyalgia Treatment Shows Promise in Study

Blunted Anti-Inflammatory Response to Exercise Increases Fibromyalgia Symptoms

Fibromyalgia Associated with Coronary Heart Disease

Happiness, Gratitude and Appreciation

Cytokine and Chemokine Profiles in Fibromyalgia, RA and Lupus: A Potentially Useful Tool in Differen...

FDA Approves Hysingla ER – Extended-Release Hydrocodone with Abuse-Deterrent Properties

5 Safety Tips for the Holidays for Persons Living with Fibromyalgia and Myofascial Pain Syndrome

Sense of Smell Impaired in Fibromyalgia Patients

 
Print Page
Email Article

A Bloodspot-Based Diagnostic Test for Fibromyalgia

  [ 15 votes ]   [ Discuss This Article ]
www.ProHealth.com • May 20, 2013


Editor's comment:  This is the second study in six months to investigate a potential diagnostic blood test for fibromyalgia.  The earlier study, published in December, 2012, measured cytokine levels and was able to distinguish FM patients from healthy controls.  This study uses spectral and metabolomic analysis and was able to distinguish FM patients from patients with osteoarthritis or rheumatoid arthritis.  

A bloodspot-based diagnostic test for fibromyalgia syndrome and related disorders

By Kevin V. Hackshaw, et al.

Abstract:

The aim of this study was to investigate the ability of a rapid biomarker-based method for diagnosis of fibromyalgia syndrome (FM) using mid-infrared microspectroscopy (IRMS) to differentiate patients with FM from those with osteoarthritis (OA) and rheumatoid arthritis (RA), and to identify molecular species associated with the spectral patterns.

Under IRB approval, blood samples were collected from patients diagnosed with FM (n = 14), RA (n = 15), or OA (n = 12). Samples were prepared, placed onto a highly reflective slide, and spectra were collected using IRMS. Spectra were analyzed using multivariate statistical modeling to differentiate groups. Aliquots of samples also were subjected to metabolomic analysis.

IRMS separated subjects into classes based on spectral information with no misclassifications among FM and RA or OA patients. Interclass distances of 15.4 (FM vs. RA), 14.7 (FM vs. OA) and 2.5 (RA vs. OA) among subjects, demonstrating the ability of IRMS to achieve reliable resolution of unique spectral patterns specific to FM.

Metabolomic analysis revealed that RA and OA groups were metabolically similar, whereas biochemical differences were identified in the FM that were quite distinctive from those found in the other two groups. Both IRMS and metabolomic analysis identified changes in tryptophan catabolism pathway that differentiated patients with FM from those with RA or OA.

Source:
Analyst, April 17, 2013. By Kevin V. Hackshaw, Luis Rodriguez-Saona, Marçal Plans, Lauren N. Bell and C. A. Tony Buffington. Departments of Internal Medicine, Division of Rheumatology, The Ohio State University, Columbus, OH 43210, USA.




Please Discuss This Article:   Post a Comment 



[ Be the first to comment on this article ]




 
Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Our FREE
Newsletter
Subscribe Now!
Receive up-to-date ME/CFS & Fibromyalgia treatment and research news
 Privacy Guaranteed  |  View Archives

Save on Nutritional Supplement Orders

Featured Products

Optimized Curcumin Longvida® by ProHealth Optimized Curcumin Longvida® by ProHealth
Supports Cognition, Memory & Overall Health
FibroSleep™ by ProHealth FibroSleep™ by ProHealth
The All-in-One Natural Sleep Aid
Fibro Freedom™ Fibro Freedom™
Soothes, strengthens & revitalizes
B-12 Extreme™ B-12 Extreme™
The Most Potent Vitamin B-12 on Earth
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function

Natural Remedies

Front Line Defense Against Colds & Flu - Support for Healthy Immune System Balance Front Line Defense Against Colds & Flu - Support for Healthy Immune System Balance
Itching to Find Dry Skin Relief? Itching to Find Dry Skin Relief?
Fatigue & Fibro Fog: Could You Have a B-12 Deficiency? Fatigue & Fibro Fog: Could You Have a B-12 Deficiency?
The Remarkable Benefits of Reishi Medicinal Mushrooms The Remarkable Benefits of Reishi Medicinal Mushrooms
Undenatured Type II Collagen - Chicken Soup for Your Joints Undenatured Type II Collagen - Chicken Soup for Your Joints

FIBROMYALGIA RESOURCES
What is Fibromyalgia?
Fibromyalgia Diagnosis
Fibromyalgia Symptoms
Fibromyalgia Treatments
| CFS RESOURCES
What is CFS?
ME/CFS Diagnosis
ME/CFS Symptoms
ME/CFS Treatments
| FORUMS
Fibromyalgia
ME/CFS
ADVANCED MEDICAL LABS
WHOLESALE  |  AFFILIATES
GUARANTEE  |  PRIVACY
CONTACT US
LIBRARY
RSS
SITE MAP
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing