ProHealth fibromyalgia Vitamin and Natural Supplement Store and Health
Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help

|
|
|

Trending News

Autoimmune Research Opening Up New Options for Chronic Pain Sufferers

Where Fibromyalgia and Chronic Fatigue Syndrome Part Ways (and Where They Don't)

Lidocaine Injections Found to Reduce Hypersensitivity to Pain in Fibromyalgia Patients

Celiac Symptoms in Fibromyalgia Patients

Does Fibromyalgia Diet = Deprivation?

Why Pain, Fatigue, FibroFog, and Sleep Are Results Symptoms

Prevalence of Falls in Fibromyalgia Patients

FDA Approves New Type of Sleep Medication

How to Become a Fibromyalgia Truth Sleuth

VIDEO: Healthy Eating and Fibromyalgia

 
Print Page
Email Article

From Our Readers: Comments & Suggestions – 10/23/13

  [ 4 votes ]   [ Discuss This Article ]
www.ProHealth.com • October 23, 2013


From Our Readers: Comments & Suggestions – 10/23/13. Image by pixbox77 FreeDigitalPhotos.net
Image by pixbox77 FreeDigitalPhotos.net

Some Patients Recommend Solutions for IBS

Re: "Coming Clean on a Dirty Secret: Irritable Bowel Syndrome"

I also endured IBS-D for at least 40 years,. It was embarrassing, and nothing really helped except Cholestryamine and Immodium. Last year, however, I saw a specialist about an unrelated issue, and after reading my history said, "why are you putting up with this?" I told him I wasn't there for IBS - I was used to it, but he continued. He checked my blood, found I was severely malnourished ( though I eat a healthy, balanced diet) because of my IBS- D. He said, "No gluten, no dairy"......within days things began to change. He gave me supplements to heal my gut (for about 3 months). Within 6 months, I can confidently say I am free of IBS-D, I did not believe this was possible. It is, for me, a small price to pay for not worrying about bathrooms after every meal. – rskra

---------------

IBS is often cured - gone forever with 4.5mg of low dose naltrexone. Might not work for everyone but there have been enough success stories that it is worth trying. I use the word cure - not afraid to do so when something is gone for years even when not taking the LDN. I strongly urge everyone to research ldn and IBS... – panet

_________________________

Quality of Life After Antidepressants

Re: "Quality of Life for Fibromyalgia Patients Worsens after Taking Antidepressants for a Year"

This is scary as heck! I certainly hope that more studies are done very soon about this. I am just getting ready to try Cymbalta. I had a horrible reaction to Lyrica--though it helped pain tremendously. This information in this study, even though about a very small study, makes me extremely reluctant to try Cymbalta or Savella. – bfmanning 

_________________________


Brainstem Dysfunction in FM Patients

Re: "Evidence of Brainstem Dysfunction in Fibromyalgia Patients"

I studied reflex and other prepulse inhibition under the influence of cannabinoids. This same phenomenon occurs under the influence of many neurological drugs. It also occurs in some forms of schizophrenia. It implies to me that the immune system cyokines, probably Il-6 and TNF-alpha as well as chronically elevated IFN-gamma are behind this lack of excitation inhibition maybe via impaired neuron-mitochondrial function. – IanH 

_________________________


I Disagree with FM and Celiac Disease Study Results

Re: "Fibromyalgia and Celiac Disease: Media Hype or an Emerging Problem?"

I completely disagree with what is said here.. I was diagnosed with fibro myalgia 2 years ago and I was in so much pain it was unbearable, and I was only 19 at the time and I used to be athletic, I had tendinitis in almost every place possible, back pain that limited me from so much, nausea every single day and NOTHING worked the doctors just kept saying it was fibro myalgia and gave me more meds.. finally my boyfriend suggested I go gluten free and i did, eventually 100% and guess what a year later ALL my pains and nausea are gone! And I'm off all the meds Dr's had me on.. moral of the story people with fibro myalgia should be tested for celiac or go on a GF diet bwcause if I didn't I wouldnot be happy and living life again. – dancer4109

_________________________


Epigenetics Study Points to Treatment Possibilities

Re: "Epigenetic Alterations in Women with Fibromyalgia"

What a great study. It shows just how deep this illness goes. I would like to see the same study done on people with ME. Some of the genes involved will be slightly different but some will be the same. I do suspect the elevated levels of micronuclei will be similar. Also the aberrant methylation should show up similarly.

Treatment! Well it does point us in a direction of nutritional epigenetics. Current treatments are hopeless.

In the nutritional field, epigenetics is very important, because nutrients can affect the expression of genes at the transcriptional level. Folate, B-12, methionine, choline, and betaine can affect DNA methylation and histone methylation through altering 1-carbon metabolism.

Two metabolites of 1-carbon metabolism can affect methylation of DNA and histones: S-adenosylmethionine (AdoMet)5, which is a methyl donor for methylation reactions, and S-adenosylhomocysteine (AdoHcy), which is a product inhibitor of methyltransferases.

Other water-soluble B vitamins like b7, b3, and b5 also play important roles in histone modifications. B7 (biotin) is a substrate of histone biotinylation. B3 (niacin) is involved in histone ADP-ribosylation as a substrate of poly(ADP-ribose) polymerase as well as histone acetylation as a substrate of Sirtuin1, which functions as histone deacetylase (HDAC).

NAD-dependent protein deacetylase links transcription regulation directly to intracellular energetics and participates in the coordination of several separated cellular functions such as cell cycle, response to DNA damage, metabolism, apoptosis and autophagy. It modulates chromatin function through deacetylation of histones and can promote alterations in the methylation of histones and DNA, which leads to transcriptional repression. It deacetylates a broad range of transcription factors and coregulators, thereby regulating target gene expression positively and negatively

Pantothenic acid is a part of CoA to form acetyl-CoA, which is the source of acetyl group in histone acetylation.

Some food components directly affect enzymes involved in epigenetics. Eg, genistein and tea catechin affects DNA methyltransferases. Resveratrol inhibits HDAC and curcumin inhibits histone acetyltransferases (HAT).

There is plenty to do now with your treatment. No cure sure but you can influence your FM by increasing the substrates that control methylation. – IanH



Please Discuss This Article:   Post a Comment 



[ Be the first to comment on this article ]




 
Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Our FREE
Newsletter
Subscribe Now!
Receive up-to-date ME/CFS & Fibromyalgia treatment and research news
 Privacy Guaranteed  |  View Archives

Save on Your Next Order

Featured Products

Fibro Freedom™ Fibro Freedom™
Soothes, strengthens & revitalizes
B-12 Extreme™ B-12 Extreme™
The Most Potent Vitamin B-12 on Earth
FibroSleep™ by ProHealth FibroSleep™ by ProHealth
The All-in-One Natural Sleep Aid
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Optimized Curcumin Longvida® by ProHealth Optimized Curcumin Longvida® by ProHealth
Supports Cognition, Memory & Overall Health

Natural Remedies

More Weight Loss than Any Other Discovery in Supplement History More Weight Loss than Any Other Discovery in Supplement History
Rejuvenating the Brain - How PQQ Helps Power Up Mental Processing Rejuvenating the Brain - How PQQ Helps Power Up Mental Processing
The Remarkable Benefits of Reishi Medicinal Mushrooms The Remarkable Benefits of Reishi Medicinal Mushrooms
Sleep Like a Baby in Nature's Cradle Sleep Like a Baby in Nature's Cradle
Three-Step Strategy to Reverse Mitochondrial Aging Three-Step Strategy to Reverse Mitochondrial Aging

FIBROMYALGIA RESOURCES
What is Fibromyalgia?
Fibromyalgia 101
Fibromyalgia Symptoms
Fibromyalgia Treatments
| CFS RESOURCES
What is CFS?
ME/CFS 101
ME/CFS Symptoms
ME/CFS Treatments
| FORUMS
Fibromyalgia
ME/CFS
ADVANCED MEDICAL LABS
WHOLESALE  |  AFFILIATES
GUARANTEE
CONTACT US
PRIVACY
RSS
SITE MAP
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing