ProHealth fibromyalgia Vitamin and Natural Supplement Store and Health
Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help

|
|
|

Trending News

Gastrointestinal Problems in Fibromyalgia

The Fibromyalgia Energy Crisis: A Balancing Act

New Restrictions on Painkillers: Tramadol and Hydrocodone

The 2013 Fibromyalgia Alternative Diagnostic Criteria: Interpretation for Patients and Providers

Nerves, Estrogen, Dr. Mikovits and Paradoxes: The INTiDYN Approach to Fibromyalgia and Chronic Fatig...

Hypersensitivity to Non-Painful Events May be Part of Pathology in Fibromyalgia

Alzheimer's Drug May Benefit Fibromyalgia Patients

Energy-Boosting Fibromyalgia Superfoods

SURVEY RESULTS: Pain Treatments

Management of Fibromyalgia Syndrome: Review of Evidence

 
Print Page
Email Article

Functional MRI Demonstrates Effectiveness of Lyrica (pregabalin) in Reducing Fibromyalgia Pain

  [ 2 votes ]   [ Discuss This Article ]
www.ProHealth.com • October 26, 2013


Note: You may read the full text of this article free HERE.

Evaluation of the effectiveness of pregabalin in alleviating pain associated with fibromyalgia: using functional magnetic resonance imaging study.

By Seong-Ho Kim, et al.

Abstract:

PURPOSE: To assess the efficacy of pregabalin by showing differences in the neuronal activities of fibromyalgia (FM) patients before and after longitudinal treatment using functional magnetic resonance imaging (fMRI).

MATERIALS AND METHODS:
In total, 21 female patients with FM and 11 age- and gender-matched healthy controls participated. FM patients underwent fMRI at baseline and following pharmacological therapy with pregabalin to diminish their pain. Pressure-pain stimuli were delivered on the subject's thumbnail bed during fMRI scans. Brain activation regions in fMRI were evaluated for longitudinal changes using a paired t-test. Changes in clinical features were also assessed with the Fibromyalgia Impact Questionnaire (FIQ), Brief Fatigue Inventory (BFI), Beck Depression Inventory (BDI), Widespread Pain Index (WPI), Symptom Severity Scale Score (SSS), and State-Trait Anxiety Inventory (STAI).

RESULTS:
Clinical scores were reduced significantly following therapy with five of the six clinical tests (FIQ, BFI, BDI, WPI, SSS; p < 0.05). Brain activation post-treatment was significantly lower than that pre-treatment in 13 regions of the brain (p < 0.001).

CONCLUSIONS:
Our findings confirm that pregabalin influences aspects of the whole pain matrix, using fMRI, inducing longitudinal changes in neuronal activity during the pain state, and that it reduces pain and other core symptoms of FM. This method could be applied to other longitudinal clinical trials of pharmacological treatments for FM.

Source:
PLoS One, September 6, 2013. By Seong-Ho Kim, Youngho Lee, Sunggun Lee and Chi-Woong Mun.  Division of Rheumatology, Department of Internal Medicine, Haeundae Paik Hospital, College of Medicine, Inje University, Haeundae-gu, Busan, South Korea.




Please Discuss This Article:   Post a Comment 



[ Be the first to comment on this article ]




 
Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Our FREE
Newsletter
Subscribe Now!
Receive up-to-date ME/CFS & Fibromyalgia treatment and research news
 Privacy Guaranteed  |  View Archives

Save on Vitamins and Supplements

Featured Products

B-12 Extreme™ B-12 Extreme™
The Most Potent Vitamin B-12 on Earth
Fibro Freedom™ Fibro Freedom™
Soothes, strengthens & revitalizes
Guaifenesin FA™ Guaifenesin FA™
Natural Expectorant Relieves Chest Congestion
Optimized Curcumin Longvida® by ProHealth Optimized Curcumin Longvida® by ProHealth
Supports Cognition, Memory & Overall Health
Hydroxocobalamin Extreme™ Hydroxocobalamin Extreme™
The B-12 your brain needs for detox & sharpness

Natural Remedies

More Weight Loss than Any Other Discovery in Supplement History More Weight Loss than Any Other Discovery in Supplement History
"It's Not Easy Being Green" - But It Is Healthy
Preserving Cognitive Function with Aging Preserving Cognitive Function with Aging
Sunshine Vitamin Has D-lightful Health Benefits Sunshine Vitamin Has D-lightful Health Benefits
Shoo Pain, Don't Bother Me - Top 10 Nutrients to Take Back Your Life Shoo Pain, Don't Bother Me - Top 10 Nutrients to Take Back Your Life

FIBROMYALGIA RESOURCES
What is Fibromyalgia?
Fibromyalgia 101
Fibromyalgia Symptoms
Fibromyalgia Treatments
| CFS RESOURCES
What is CFS?
ME/CFS 101
ME/CFS Symptoms
ME/CFS Treatments
| FORUMS
Fibromyalgia
ME/CFS
ADVANCED MEDICAL LABS
WHOLESALE  |  AFFILIATES
GUARANTEE
CONTACT US
PRIVACY
RSS
SITE MAP
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing