Activate Now
ProHealth fibromyalgia Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help

Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Do You Have These Fibromyalgia Symptoms of Systemic Dysfunction?

Fibromyalgia – The Savella Story

Meet Devin Starlanyl: Fibromyalgia and Chronic Myofascial Pain Expert

Which Infection Causes CFS & Fibromyalgia?

The "Mind Diet" Reduces the Risk Of Alzheimer’s Dementia. Might It Also Help the Brain Fog Found Wit...

Need Help with Pain Management? There's an App for That

Simplifying Nutritional Support in CFS & Fibromyalgia

6 Reasons Why Trigger Point Injections Aren't Helping Your Fibromyalgia

How Multiple Chronic Illnesses Shaped One Woman Into a Patient Advocate

VIDEO: Fibromyalgia & Your Stress-Coping Savings Account

Print Page
Email Article

Higher omega-3 levels linked to better cognitive function following depression in older adults

  [ 8 votes ]   [ Discuss This Article ] • April 6, 2012

Associations between omega-3 PUFA concentrations and cognitive function after recovery from late-life depression
– Source: American Journal of Clinical Nutrition, Feb 2012

By CC Chiu, et al.

[Note: Though omega-3 PUFAs can be derived from animal sources, especially fish and krill oils, the omega-3 food chain originates in plants – e.g., seaweed & algae eaten by krill and fish. The omega-3s in fish oil and krill oil are called eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). The omega-3 found in plant sources such as flaxseed is called alpha-linolenic acid (ALA). The red blood cells of the subjects in this study were tested for all of these.]

Background: Lower concentrations of n-3 PUFAs [omega-3 polyunsaturated fatty acids]:

• Have been reported to be associated with cognitive impairment and dementia,

• But also with depression - itself a potential risk factor for cognitive decline.

Objective: The aims of this study were to investigate associations between n-3 PUFA concentrations in erythrocyte [red blood cell] membrane or plasma [liquid in which blood cells are suspended] and cognitive function in an at-risk sample of older people with previous major depression, and to explore specificity with respect to cognitive domains.

• A cross-sectional sample of 132 eligible participants who had recovered from major depression (mean +/- SD age: 67.8 plus/minus 6.6 years) were enrolled from outpatient psychiatric services.

• A series of cognitive tests and a structured questionnaire were administered.

• Fasting blood samples were collected for n-3 PUFA measurements.

Results: Higher EPA and total n-3 PUFA concentrations and a lower ratio of arachidonic acid-to-EPA in erythrocyte membranes were associated with a higher cognitive composite score: independent of age and sex, but no longer significant after adjustment for education. No associations were found with plasma concentrations of any fatty acid. [Arachidonic acid is a type of omega-6 PUFA most plentiful in red meats that is essential for growth of skeletal muscle but considered harmful when in a higher ratio vs. omega-3s.]

Considering individual cognitive tests the strongest and most consistent correlations were found between immediate recall and concentrations of total n-3 PUFAs and alpha-linolenic acid (ALA) in erythrocytes, which were observed only in participants with recurrent depression.

• Total erythrocyte n-3 PUFA concentrations are positively associated with cognitive function, particularly immediate recall, in older people with previous depression. [Higher levels, better cognitive function & immediate recall, and vice-versa.]

• Lower concentrations of n-3 PUFAs or ALA in erythrocyte membranes may be good predictors for cognitive impairment in older people with previous recurrent depression.

Source: American Journal of Clinical Nutrition, Feb 2012;95(2):420-407. PMID: 22218153, by Chiu CC, Frangou S, Chang CJ, Chiu WC, Liu HC, Sun IW, Liu SI, Lu ML, Chen CH, Huang SY, Dewey ME, Stewart R. Department of Psychiatry, Taipei City Psychiatric Center, Taipei City Hospital, Taiwan.

Please Discuss This Article:   Post a Comment 

[ Be the first to comment on this article ]

Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Subscribe Now!
Receive up-to-date ME/CFS, Fibromyalgia & Lyme Disease treatment and research news
 Privacy Guaranteed  |  View Archives

Vitamins and Supplements for Fibromyalgia Support

Featured Products

Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Guaifenesin FA™ Guaifenesin FA™
Natural Expectorant Relieves Chest Congestion
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Arctic Select Krill Oil™ Arctic Select Krill Oil™
Your Ultimate Source of Omega-3
Fibro Freedom™ Fibro Freedom™
Soothes, strengthens & revitalizes

Natural Remedies

"It's Not Easy Being Green" - But It Is Healthy
Green Coffee Extract: Unique Obesity Intervention Green Coffee Extract: Unique Obesity Intervention
Vitamin E: Super Antioxidant We Only Thought We Knew Vitamin E: Super Antioxidant We Only Thought We Knew
Can Glycine + Amino Acids Be the Secret to Deep, Rejuvenating Sleep? Can Glycine + Amino Acids Be the Secret to Deep, Rejuvenating Sleep?
Itching to Find Dry Skin Relief? Itching to Find Dry Skin Relief?

What is Fibromyalgia?
Fibromyalgia Diagnosis
Fibromyalgia Symptoms
Fibromyalgia Causes
Fibromyalgia Treatments
Fibromyalgia Diet
Fibromyalgia Medications
M.E. & CFS
What is M.E./CFS?
M.E./CFS Diagnosis
M.E./CFS Symptoms
M.E./CFS Causes
M.E./CFS Treatments
M.E./CFS Diet
M.E./CFS Medications
What is Lyme Disease?
Lyme Disease Diagnosis
Lyme Disease Symptoms
Lyme Disease Causes
Lyme Disease Treatments
Lyme Disease Diet
Lyme Disease Medications
M.E. & CFS
Lyme Disease
General Health
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing