ProHealth fibromyalgia Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

What Does Fibromyalgia Feel Like?

VIDEO: What is Fibromyalgia?

ADHD (Attention Deficit Hyperactivity Disorder) May Be Common in Fibromyalgia

Fibromyalgia and Thyroid Resistance

Be Your Own Researcher: Treat Chronic Pain as a Daily Experiment

Five Things You Should Never Say to a Person with Chronic Illness...And What To Say Instead

Fibromyalgia has a high prevalence and impact in cardiac failure patients.

Journey to a Diagnosis

My Current Treatment Protocol for Chronic Lyme and Fibromyalgia

The Depression Puzzle: Are Anti-inflammatories Better Than Antidepressants? An ME/CFS and FM Perspec...

 
Print Page
Email Article

Neurological effects of dietary glutamates may contribute to fibromyalgia symptoms for many

  [ 82 votes ]   [ Discuss This Article ]
www.ProHealth.com • July 9, 2012


Article:
The effect of dietary glutamate on fibromyalgia and irritable bowel symptoms
- Source: Clinical and Experimental Rheumatology, Jul 4, 2012

By KF Holton, et al.

[Note: glutamic acid (glutamate) is “the chief excitatory neurotransmitter in the human brain” and aspartate can excite neurons in place of glutamate. Many neurodegenerative & cognitive problems are believed to involve the 'excitotoxin’ activity of glutamate/aspartate. Cells can synthesize one from the other, but these chemicals are both also common in foods. For example wheat gluten is 43% glutamate, milk protein 23%, gelatin 12%; MSG is glutamate and Aspartame is aspartate.]

Abstract:
Objectives: To examine the effects of a challenge with monosodium glutamate (MSG) as compared to placebo on the symptoms of fibromyalgia (FM), in participants who initially experienced >30% remission of symptoms on an excitotoxin elimination diet.

Methods: Fifty-seven FM patients who also had irritable bowel syndrome (IBS) were placed on a 4-week diet that excluded dietary additive excitotoxins including MSG and aspartame. Thirty-seven people completed the diet and 84% of those reported that >30% of their symptoms resolved, thus making them eligible to proceed to challenges.

Subjects who improved on the diet were then randomized to a 2-week double-blind placebo-controlled crossover challenge with MSG or placebo for 3 consecutive days each week. The primary outcome measure was total symptom score. Secondary outcome measures included visual analogue pain scales (VAS for FM and IBS), an IBS Quality of Life Questionnaire (IBS QOL) and the Fibromyalgia Impact Questionnaire-Revised (FIQR).

Repeated measures ANOVA was used to analyze crossover challenge results.

Results: The MSG challenge, as compared to placebo, resulted in:

• A significant return of symptoms (total symptom score, p<0.02);

• A worsening of fibromyalgia severity as determined by the FIQR (p<0.03);

• Decreased quality of life in regards to IBS symptoms (IBS QOL, p<0.05);

• And a non-significant trend toward worsening FM pain based on visual analogue scale (VAS, p<0.07).

Conclusions: These findings suggest that dietary glutamate may be contributing to FM symptoms in some patients. Future research on the role of dietary excitotoxins in FM is warranted.

Source: Clinical and Experimental Rheumatology, Jul 4, 2012. PMID:22766026, by Holton KF, Taren DL, Thomson CA, Bennett RM, Jones KD. Departments of Orthopedics and Rehabilitation, Oregon Health & Science University, Portland, OR, USA. [Email: holtonk@ohsu.edu]





Post a Comment

Featured Products From the ProHealth Store
Hydroxocobalamin Extreme™ Fibro Freedom™ Energy NADH™ 12.5mg


Article Comments



Be the first to comment on this article!

Post a Comment


 
Optimized Curcumin Longvida with Omega-3

Featured Products

Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Fibro Freedom™ Fibro Freedom™
Soothes, Strengthens & Revitalizes
B-12 Extreme™ B-12 Extreme™
The Most Potent Vitamin B-12 on Earth
Hydroxocobalamin Extreme™ Hydroxocobalamin Extreme™
The B-12 Your Brain Needs for Detox & Sharpness
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health

Natural Remedies

How to Jump-start and Sustain Energy Production in CFS How to Jump-start and Sustain Energy Production in CFS
Dreaming of a Good Night's Sleep? Dreaming of a Good Night's Sleep?
Breaking Through the Mental Fog Breaking Through the Mental Fog
Supercharge Your Brain with Two Powerful Nutrients Supercharge Your Brain with Two Powerful Nutrients
Natural Support for Mood, Sleep and Mental Focus? L-theanine Natural Support for Mood, Sleep and Mental Focus? L-theanine

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2018 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map