IBS patients' willingness to take risks with medications
– Source: American Journal of Gastroenterology, June 2012
By Brian E Lacy, MD, PhD, et al.
Objectives: We explored irritable bowel syndrome (IBS) patients’ impulsivity and risk-taking behavior and their willingness to take medication risks.
Methods: A validated questionnaire assessed the illness experience of IBS patients. A standard gamble evaluated respondents’ willingness to take medication risks.
• IBS patients with severe symptoms were more willing to take significant medication risks than those with mild or moderate symptoms.
• Impulsivity scores were not associated with an increased likelihood of taking medication risks.
• Age, gender, and years of IBS symptoms were not associated with medication risk-taking behavior.
• IBS patients reported they would accept a median 1% risk of sudden death for a 99% chance of cure for their symptoms using a hypothetical medication.
Conclusions: IBS patients are willing to take significant medication risks to cure their symptoms. To counsel patients effectively, physicians must determine and understand IBS patients’ risk aversion.
Source: American Journal of Gastroenterology, June 2012;107, 804-809. DOI:10.1038/ajg.2011.485, by Lacy BE, Everhart KK, Weiser KT, DeLee R, Strobel S, Siegel C, Crowell MD. Division of Gastroenterology and Hepatology, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire; Division of Gastroenterology, Mayo Clinic, Scottsdale, Arizona, USA. [E-mail: Brian.E.Lacy@Hitchcock.org]