ProHealth fibromyalgia Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

What does fibromyalgia feel like?

Response to vitamin B12 and folic acid in myalgic encephalomyelitis and fibromyalgia.

Fibromyalgia and Thyroid Resistance

ADHD (Attention Deficit Hyperactivity Disorder) May Be Common in Fibromyalgia

Be Your Own Researcher: Treat Chronic Pain as a Daily Experiment

Five Things You Should Never Say to a Person with Chronic Illness...And What To Say Instead

You Can Use Mindfulness to Choose How to Live

Fibro-mates, GI Disturbance, and Hypnosis

The International Support Fibromyalgia Network (ISFN)

My current treatment protocol for chronic Lyme and fibromyalgia

 
Print Page
Email Article

Strong new evidence that MS risk affected by birth month, mom's vitamin D status

  [ 9 votes ]   [ Discuss This Article ]
www.ProHealth.com • November 20, 2012


Article:
The month of birth effect in multiple sclerosis: Systematic review, meta-analysis and effect of latitude
- Source: Journal of Neurology, Neurosurgery & Psychiatry, Nov 14, 2012. 

By Ruth Dobson, et al.

[Note: The free full text PDF of this article is available here. It reports on a first-time analysis of several large populations living at latitudes in the Northern Hemisphere where UV light is insufficient to produce vitamin D in an expectant mother's skin between October and March. Significantly greater risk of MS was found in people born at those latitudes during April and May (after the winter months) than for those born during October and November (after the summer months).]

Background: Month of birth has previously been described as a risk factor for multiple sclerosis (MS). This has been hypothesized to be related to maternal vitamin D levels during pregnancy, although conclusive evidence to support this is lacking.

To date, no large studies of latitudinal variation in the month of birth effect have been performed to advance this hypothesis.

Methods: Previously published data on month of birth from 151,978 MS patients were compared to expected birth rates. A linear regression model was used to assess the relationship between latitude and observed: expected birth ratio of MS patients for each month.

Results: Analysis of all reported data demonstrated a significant excess of MS risk in those born in April (observed-to-expected 1.05, p=0.05) and reduction in risk in those born in October (0.95, p=0.04) and November (0.92 p=0.01).

A conservative analysis of 78,488 patients revealed an excess MS risk in those born in April (1.07, p=0.002) and May (1.11, p=0.0006), and a reduced risk in those born in October (ratio 0.94, p=0.004) and November (0.88, p=0.0002). [A risk ratio of 1.0 would indicate no difference in risk; thus the risk ratio of 1.11 for May would indicate risk above expected of 11%, and the 0.88 ratio for November would indicate 12% less risk than expected for November births.]

A significant relationship between latitude and observed-to-expected ratio was demonstrated in December, and borderline significant relationships in May and August.

Conclusions: Month of birth has a significant effect on subsequent MS risk. This is likely to be due to ultraviolet light exposure and maternal vitamin D levels, as demonstrated by the relationship between risk and latitude.

Source: Journal of Neurology, Neurosurgery & Psychiatry, Nov 14, 2012. Dobson R, Giovannoni G, Ramagopalan S. Queen Mary University of London, Blizard Institute, Barts and the London School of Medicine and Dentistry, London; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford; Department of Clinical Neurology, John Radcliffe Hospital, Oxford, UK. [Email: ruth.dobson@qmul.ac.uk]





Post a Comment

Featured Products From the ProHealth Store
Fibro Freedom™ Energy NADH™ 12.5mg FibroSleep™


Article Comments



Be the first to comment on this article!

Post a Comment


 
Optimized Curcumin Longvida with Omega-3

Featured Products

B-12 Extreme™ B-12 Extreme™
The Most Potent Vitamin B-12 on Earth
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Fibro Freedom™ Fibro Freedom™
Soothes, Strengthens & Revitalizes
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid

Natural Remedies

The Cellular Enzyme That Promotes Longevity And Reduces Fat Storage The Cellular Enzyme That Promotes Longevity And Reduces Fat Storage
Coenzyme Q10 - The Energy Maker Coenzyme Q10 - The Energy Maker
Vital Molecule Increases Cellular Energy and Improves Cognitive Function Vital Molecule Increases Cellular Energy and Improves Cognitive Function
Herbal Rescue for High Blood Sugar Herbal Rescue for High Blood Sugar
Strontium - The Missing Mineral for Strong Bones Strontium - The Missing Mineral for Strong Bones

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2018 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map