ProHealth fibromyalgia Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help

|
|
|

Trending News

Drug Combo in Pridgen Antiviral Fibromyalgia Trial Identified – Some Results Available

7 Fibromyalgia Seasonal Stress Strategies

Blunted Anti-Inflammatory Response to Exercise Increases Fibromyalgia Symptoms

Fibromyalgia Associated with Coronary Heart Disease

Happiness, Gratitude and Appreciation

Cytokine and Chemokine Profiles in Fibromyalgia, RA and Lupus: A Potentially Useful Tool in Differen...

FDA Approves Hysingla ER – Extended-Release Hydrocodone with Abuse-Deterrent Properties

5 Safety Tips for the Holidays for Persons Living with Fibromyalgia and Myofascial Pain Syndrome

Sense of Smell Impaired in Fibromyalgia Patients

Energy Breakthrough - One Fibromyalgia Patient’s Fortuitous Discovery

 
Print Page
Email Article

Strong Evidence of a Genetic Link in Fibromyalgia

  [ 63 votes ]   [ 2 Comments ]
www.ProHealth.com • January 4, 2013


Strong Evidence of a Genetic Link in FibromyalgiaArticle:

The fibromyalgia family study: A genome-scan linkage study.

– Source:  Arthritis and Rheumatism, December 28, 2012. [Epub ahead of print]

By Lesley M. Arnold, et al.



Abstract:

Objective:  Familial aggregation of fibromyalgia has been increasingly recognized. The goal of the current study was to conduct a genome wide linkage scan to identify susceptibility loci for fibromyalgia.

Methods:  We genotyped members of 116 families from the Fibromyalgia Family Study and performed a model-free genome-wide linkage analysis of fibromyalgia with 341 microsatellite markers, using the Haseman-Elston regression approach.

Results:  The estimated sibling recurrence risk ratio (?(s) ) for fibromyalgia was 13.6 (95% CI: 10.0-18.5), based on a reported population prevalence of 2%. Genome-wide suggestive evidence of linkage was found at marker D17S2196 (Empirical P =0.00030) and D17S1294 (Empirical P =0.00035) on chromosome 17p11.2-q11.2.

Conclusion:  The estimated sibling recurrence risk ratio suggests a strong genetic component of fibromyalgia.

This is the first study to report genome-wide suggestive linkage of fibromyalgia to the chromosome 17p11.2-q11.2 region.

Further investigation of these multi-case families from the Fibromyalgia Family Study is warranted to identify potential causal risk variants for fibromyalgia. © 2012 American College of Rheumatology.

Source:  Arthritis and Rheumatism, December 28, 2012. [Epub ahead of print]. By Lesley M. Arnold, I. Jon Russell, Muhammad B. Yunus, M.A. Khan, I. Kushner, J.M. Olson, S.K. Iyengar. Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, Ohio. E-mail: Lesley.Arnold@uc.edu.




Please Discuss This Article:   Post a Comment 

nice to know
Posted by: roge
Jan 4, 2013
genetic link was highly suspected for years and good to get more confirmation but researchers what are you doing to help better treat this horrible disease and gain a better understanding of the pathology . I can assure everyone with FM would rather have that answered then if this runs in families - can we please get come priority setting here with regards to how research dollars are spent here - man o man.
Reply Reply

"Genetic link?" I hope to shout!
Posted by: tursiops
Jan 16, 2013
I got sick in June 1981, at age 42. My daughter got sick several years later, at age 34. Within a year, she was no longer
able to work.
Recently, she has in addition, been diagnosed with MS.

My son, a few years later, came down with it too, he was 42.

And can anybody help me get the full spectrum of tests for hypo-
thyrodism? My doctor absolutely REFUSES to do anything but the
THS test,citing it as the most 'sensitive.' Everything I've read
about it shows that, if you don't know the results of the T3, T4
tests, you aren't getting the full picture. And, given that I am
a tall, plus size lady, does the dosage for thyroid replacement
for a 5' tall, 98 pound person seem adequate for someone larger?
I have taken him articles written by doctors, for doctors, and
he won't even read them. Why do I keep him as my PCP? I live in
a rural area. Only choice.
Reply Reply
 
Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Our FREE
Newsletter
Subscribe Now!
Receive up-to-date ME/CFS & Fibromyalgia treatment and research news
 Privacy Guaranteed  |  View Archives

Save on Nutritional Supplement Orders

Featured Products

FibroSleep™ by ProHealth FibroSleep™ by ProHealth
The All-in-One Natural Sleep Aid
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Fibro Freedom™ Fibro Freedom™
Soothes, strengthens & revitalizes
Hydroxocobalamin Extreme™ Hydroxocobalamin Extreme™
The B-12 your brain needs for detox & sharpness
B-12 Extreme™ B-12 Extreme™
The Most Potent Vitamin B-12 on Earth

Natural Remedies

"It's Not Easy Being Green" - But It Is Healthy
More Weight Loss than Any Other Discovery in Supplement History More Weight Loss than Any Other Discovery in Supplement History
Preserving Cognitive Function with Aging Preserving Cognitive Function with Aging
Repair Damaged Mitochondria and Reduce Fatigue Up to 45% Repair Damaged Mitochondria and Reduce Fatigue Up to 45%
Reversing Neurodegeneration with a New Magnesium Compound Reversing Neurodegeneration with a New Magnesium Compound

FIBROMYALGIA RESOURCES
What is Fibromyalgia?
Fibromyalgia Diagnosis
Fibromyalgia Symptoms
Fibromyalgia Treatments
| CFS RESOURCES
What is CFS?
ME/CFS Diagnosis
ME/CFS Symptoms
ME/CFS Treatments
| FORUMS
Fibromyalgia
ME/CFS
ADVANCED MEDICAL LABS
WHOLESALE  |  AFFILIATES
GUARANTEE  |  PRIVACY
CONTACT US
LIBRARY
RSS
SITE MAP
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing