ProHealth fibromyalgia Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

One Gene, Many Disorders: Could One Gene Help Explain ME/CFS, FM, POTS, IBS, EDS, IBS and Others

The Thyroid Question in Fibromyalgia and Chronic Fatigue Syndrome (ME/CFS)

The Cannabis Science Fibromyalgia Pain Patch: Fact or Fiction?

Brain Fog

Top 10 Benefits of Laughter for Fibromyalgia

Could Fibromyalgia Be A Low-Endorphin Disease?

The Difference Between Fibromyalgia Tender Points and Myofascial Trigger Points

SURVEY: Cognitive Impairment II

Chronic Christmas: Surviving the Holidays with a Chronic Illness

Top 3 Nutrients to Detox the Liver and Soothe Digestion

 
Print Page
Email Article

Enhanced Glutathione Levels in Blood and Buccal Cells by Oral Glutathione Supplementation

  [ 8 votes ]   [ Discuss This Article ]
By John P Richie et al. • www.ProHealth.com • June 20, 2013


By John P Richie et al.

Abstract

Glutathione (GSH) is the major antioxidant in nearly all cells and plays numerous roles in protection against diseases and biological insults. Previous studies in laboratory animals indicate that orally administered GSH is bioavailable and effective at enhancing tissue GSH levels. The current objective was to determine the efficacy of GSH supplementation at enhancing body stores of GSH in healthy adults.

We conducted a 6-mo randomized, double-blind, placebo controlled trial to determine the impact of GSH administration at 250 mg/day and 1000 mg/day on GSH levels in different blood components and exfoliated buccal mucosal cells. Subjects were 54 healthy adults (41 females/13 males), 28–72 yr of age (mean=46.6 yr). Compliance was >90% by pill count.

After 6 mo in the high dose group, GSH levels were increased 30–35% in RBC, plasma, and lymphocytes and 260% in buccal cells (P<0.05). In most cases, the increases were dose and time dependent and levels returned to baseline after a 1-month washout. No significant changes were observed in levels of protein bound GSH.

A battery of immune function markers was also examined after 3 mo of GSH supplementation and Natural Killer (NK) cytotoxicity was enhanced > 2-fold in the high dose group (P<0.05). Altogether, these findings are consistent with previous pre-clinical studies and indicate that long-term oral administration GSH is an effective means of enhancing body stores of GSH.

Source: The FASEB Journal. 2013;27:862.32. John P Richie, Sailnendra Nichenametla, Ana Calcagnotto, Wanda Neidig, Todd Schell, and Joshua E Muscat





Post a Comment

Featured Products From the ProHealth Store
Guaifenesin FA™ B-12 Extreme™ Energy NADH™ 12.5mg


Article Comments



Be the first to comment on this article!

Post a Comment


 
Natural Pain Relief Supplements

Featured Products

Guaifenesin FA™ Guaifenesin FA™
Helps the Body Eliminate Excess Calcium and Phosphates
Hydroxocobalamin Extreme™ Hydroxocobalamin Extreme™
The B-12 Your Brain Needs for Detox & Sharpness
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
B-12 Extreme™ B-12 Extreme™
The Most Potent Vitamin B-12 on Earth

Natural Remedies

The Remarkable Benefits of Reishi Medicinal Mushrooms The Remarkable Benefits of Reishi Medicinal Mushrooms
Block food Cravings At Their Molecular Root Block food Cravings At Their Molecular Root
The Fast-Acting Solution for Healthy Digestive Function The Fast-Acting Solution for Healthy Digestive Function
How to Jump-start and Sustain Energy Production in CFS How to Jump-start and Sustain Energy Production in CFS
SAD? Coping with Seasonal Affective Disorder SAD? Coping with Seasonal Affective Disorder

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2016 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map