ProHealth fibromyalgia Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

The best sleeping positions for pain

VIDEO: Anxiety: 11 Things We Want You to Understand

Is There a GERD—Fibro Connection?

Chronic Pain, Loneliness, Depression and Suicide

Beyond pain in fibromyalgia: insights into the symptom of fatigue.

Things to Do When You're Mostly Housebound

Stair negotiation in women with fibromyalgia: A descriptive correlational study.

Is a Good Night's Sleep at the Top of Your Wishlist?

Could a Diet Reduce the Pain in Fibromyalgia? A FODMAPS Study Suggests Yes

Tying the Brain and Body Together in Fibromyalgia?

 
Print Page
Email Article

Having enough vitamin C could help suppress leukemia

  [ Not Yet Rated ]   [ Discuss This Article ]
By Life Extension • www.ProHealth.com • September 10, 2017


Having enough vitamin C could help suppress leukemia
Reprinted with the kind permission of Life Extension.

September 1 2017. An article appearing on August 21, 2017 in Nature describes researchconducted at the University of Texas Southwestern Medical Center Children's Research Institute (CRI) that determined that hematopoietic (blood-forming) stem cells take up high levels of vitamin C which regulates their function and suppresses the development of leukemia.

Using mice that lacked an enzyme which enables most mammals to synthesize their own vitamin C, the researchers gave the animals diets that contained depleted levels of the vitamin. Rather than the anticipated loss of stem cell function, a gain in function occurred, accompanied by an increased risk of leukemia.

"Stem cells use ascorbate to regulate the abundance of certain chemical modifications on DNA, which are part of the epigenome," explained lead author Michalis Agathocleous. "The epigenome is a set of mechanisms inside a cell that regulates which genes turn on and turn off."

The authors determined that vitamin C regulates hematopoietic stem cell function partly through mechanisms involving the enzyme Tet2 which, when mutated is inactivated early in the development of leukemia. "One of the most common mutations in patients with clonal hematopoiesis is a loss of one copy of Tet2,” noted corresponding author Sean Morrison, who is the Director of the CRI. “Our results suggest patients with clonal hematopoiesis and a Tet2 mutation should be particularly careful to get 100 percent of their daily vitamin C requirement. Because these patients only have one good copy of Tet2 left, they need to maximize the residual Tet2 tumor-suppressor activity to protect themselves from cancer."

"We have known for a while that people with lower levels of ascorbate (vitamin C) are at increased cancer risk, but we haven't fully understood why,” he remarked. “Our research provides part of the explanation, at least for the blood-forming system."



Post a Comment

Featured Products From the ProHealth Store
Guaifenesin FA™ Fibro Freedom™ Hydroxocobalamin Extreme™


Article Comments



Be the first to comment on this article!

Post a Comment


 
Optimized Curcumin Longvida with Omega-3

Featured Products

B-12 Extreme™ B-12 Extreme™
The Most Potent Vitamin B-12 on Earth
Fibro Freedom™ Fibro Freedom™
Soothes, Strengthens & Revitalizes
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Guaifenesin FA™ Guaifenesin FA™
Helps the Body Eliminate Excess Calcium and Phosphates
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health

Natural Remedies

The Fast-Acting Solution for Healthy Digestive Function The Fast-Acting Solution for Healthy Digestive Function
The Fibromyalgia and Glutathione Link The Fibromyalgia and Glutathione Link
The Big Blue Fish that Helps Chase the Blues Away The Big Blue Fish that Helps Chase the Blues Away
Olea25 Olive Hydroxytyrosol Hits Astonishing 68,000+ ORAC Antioxidant Value Olea25 Olive Hydroxytyrosol Hits Astonishing 68,000+ ORAC Antioxidant Value
Herbal Inflammation Management for Whole Body Health Herbal Inflammation Management for Whole Body Health

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map