Activate Now
ProHealth fibromyalgia Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Aromatherapy Diffusers For Fibromyalgia Support

Chronic Fatigue Syndrome, Fibromyalgia and Mitchondrial Disorders: A Comparison Plus the MitoQ Trial...

Dr. Teitelbaum's 3 Steps to Fibromyalgia Pain Relief - Part 1: Understanding Fibromyalgia Pain

An Interview with Ken McKim: Educating the public about chronic illness

Repair Damaged Mitochondria and Reduce Fatigue Up to 45%

Milnacipran for pain in fibromyalgia in adults

Are All the "Feel-Good" Pathways Blocked in Fibromyalgia and Chronic Fatigue Syndrome?

5 Things I've Learned About Chronic Illness Through Mindfulness

SURVEY RESULTS: Has Your Illness Affected What You Eat?

Staying healthy from fibromyalgia is ongoing hard work

Print Page
Email Article

New Virus Research Important to Future Chronic Fatigue SyndromeTreatment

  [ 616 votes ]   [ Discuss This Article ] • December 20, 2000

One of nature's smallest motors helps viruses package their genetic material, according to new research. The findings could lead to the development of new drugs aimed at preventing the spread of viruses. Viruses are thought to play a key part in the development of CFS.

Scientists at Purdue University and the University of Minnesota have solved the three-dimensional structure of the central component of a biological motor that powers the DNA packaging system in a virus, providing scientists with their first glimpse of such a motor system.

The study, described in the December 7 issue of the scientific journal Nature, revealed how the core of a tiny motor, just millionths of a millimeter in size is constructed, and suggests how it works to pack long stretches of the virus' genetic material into its outer shell during the process of viral replication.

The results point to new opportunities in nanoscience, according to NSF program director Parag Chitnis. "One application of this work will be in developing drugs that would inhibit virus replication. Many viruses that infect humans, such as Herpes, use a similar machinery for DNA packaging," he said.

The project may provide clues as to how DNA is packaged in similar viruses - including Herpes virus, which causes human ailments such as Herpes simplex, chicken pox and shingles - and suggest ways for developing drugs that prevent illnesses caused by viral pathogens. "This study provides the first knowledge of a DNA packaging motor," said Michael Rossmann, Hanley Distinguished Professor of Biological Sciences at Purdue. "Though other motor systems have been studied in biology, this is the first motor known to translocate genetic material."

Viruses are essentially a simple parasite consisting only of an envelope that contains the genetic material ready for transportation from one host to another. They can reproduce only after infecting a host cell. Once inside a cell, the virus manipulates the cell's machinery to produce all the necessary components, including genetic material, to assemble new viruses. It is here that the biological motor is needed to fill newly assembled envelopes with their genetic material, Rossmann said. The new viruses are then released from the host cell and are free to infect other cells.

The study also will provide scientists with new insights on how molecular motors work in biology, said Dwight Anderson, professor at the University of Minnesota. "The beauty of phi29 motor is that it provides a relatively simple system to investigate the mechanism of DNA packaging," Anderson said. "Working in a micro-droplet, or an area the size of a very small drop, the motor packages a DNA about 130 times longer than the viral shell, in just three minutes.

In the study, Rossmann, along with Purdue researcher Timothy Baker and others at Purdue, and Anderson and his co-workers at Minnesota, used micro-imaging techniques - including X-ray crystallography and cryo-electron microscopy - to determine the structure of the DNA packaging motor in a virus called Bacteriophage phi29.

Bacteriophages are viruses that only infect bacteria. They are widely used in laboratory research because they are often similar in structure to human viruses. The work was made possible in part by the National Science Foundation (NSF), through its Molecular Biophysics program. The research was also funded by the National Institutes of Health and Purdue University.

Post a Comment

Featured Products From the ProHealth Store
Hydroxocobalamin Extreme™ Fibro Freedom™ Optimized Curcumin Longvida®

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products

Article Comments

Be the first to comment on this article!

Post a Comment

Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Subscribe Now!
Receive up-to-date ME/CFS, Fibromyalgia & Lyme Disease treatment and research news
 Privacy Guaranteed  |  View Archives

Repair Damaged Mitochondria and Reduce Fatigue Up to 45%

Featured Products

Hydroxocobalamin Extreme™ Hydroxocobalamin Extreme™
The B-12 your brain needs for detox & sharpness
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Guaifenesin FA™ Guaifenesin FA™
Helps the Body Eliminate Excess Calcium and Phosphates

Natural Remedies

IBS, Crohn’s Disease, Colitis, and Other Digestive Disorders IBS, Crohn’s Disease, Colitis, and Other Digestive Disorders
Stop Bacteria With Nature's Antibiotics Stop Bacteria With Nature's Antibiotics
The Remarkable Benefits of Reishi Medicinal Mushrooms The Remarkable Benefits of Reishi Medicinal Mushrooms
Vitamin K-2 – A Key Player in Cardiovascular and Bone Health Vitamin K-2 – A Key Player in Cardiovascular and Bone Health
Astaxanthin - A Little-Known but Power-Packed Nutrient Astaxanthin - A Little-Known but Power-Packed Nutrient

What is Fibromyalgia?
Fibromyalgia Diagnosis
Fibromyalgia Symptoms
Fibromyalgia Causes
Fibromyalgia Treatments
Fibromyalgia Diet
Fibromyalgia Medications
M.E. & CFS
What is M.E./CFS?
M.E./CFS Diagnosis
M.E./CFS Symptoms
M.E./CFS Causes
M.E./CFS Treatments
M.E./CFS Diet
M.E./CFS Medications
What is Lyme Disease?
Lyme Disease Diagnosis
Lyme Disease Symptoms
Lyme Disease Causes
Lyme Disease Treatments
Lyme Disease Diet
Lyme Disease Medications
M.E. & CFS
Lyme Disease
General Health
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing