Activate Now
ProHealth fibromyalgia Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Aromatherapy Diffusers For Fibromyalgia Support

Chronic Fatigue Syndrome, Fibromyalgia and Mitchondrial Disorders: A Comparison Plus the MitoQ Trial...

Dr. Teitelbaum's 3 Steps to Fibromyalgia Pain Relief - Part 1: Understanding Fibromyalgia Pain

An Interview with Ken McKim: Educating the public about chronic illness

Repair Damaged Mitochondria and Reduce Fatigue Up to 45%

Are All the "Feel-Good" Pathways Blocked in Fibromyalgia and Chronic Fatigue Syndrome?

5 Things I've Learned About Chronic Illness Through Mindfulness

SURVEY RESULTS: Has Your Illness Affected What You Eat?

Cellular Havoc: Zeroing In On The Sleep Problems in Fibromyalgia?

Staying healthy from fibromyalgia is ongoing hard work

Print Page
Email Article

Treatment of Chronic Fatigue Syndrome and Fibromyalgia with D-Ribose: An Open-label, Multicenter Study – Source: The Open Pain Journal, June 27, 2012

  [ 16 votes ]   [ Discuss This Article ]
By Jacob Teitelbaum, Janelle Jandrain, Ryan McGrew • • July 4, 2012

[Note: To read the full text of this report free, click here. For a scientific explanation of D-ribose, see “Ribose: A major component of the ‘energy molecule’ ATP" by nutrient specialist Brian Tanzer, MS, CNS. Note this study did not involve 'blinding' and was not placebo controlled - patients all were supplemented with D-ribose. At least one blinded, controlled trial is in the works, led by Leslie J Crofford, MD, at the University of Kentucky.]

Objectives: Chronic Fatigue Syndrome and Fibromyalgia (CFS/FMS) are debilitating syndromes affecting about 2%-4% of the population.

Although they are heterogeneous conditions associated with many triggers, they appear to have the common pathology of being associated with impaired energy metabolism.

As D-ribose has been shown to increase cellular energy synthesis, and was shown to significantly improve clinical outcomes in CFS/FMS in an earlier study, we hypothesized that giving D-ribose would improve function in CFS/FMS patients.

Design, Location, and Subjects:

An open-label, unblinded study in which 53 US clinics enrolled 257 patients who had been given a diagnosis of CFS/FMS by a health practitioner.

Interventions: All subjects were given D-ribose (Corvalen™), a naturally occurring pentose carbohydrate, 5-g twice a day for 3 weeks.

Outcome measures: All patients were assessed at baseline (1 week before treatment), and after 1,2, & 3 weeks using a Visual Analog Scale (1-7 points) rating energy, sleep, cognitive function, pain and overall well being.

Results: 203 patients completed the 3 week treatment trial. D-ribose treatment led to both statistically (p<.0001) and clinically highly important average improvements in all categories:

• 61.3% increase in energy

• 37% increase in overall well being

• 29.3% improvement in sleep

• 30% improvement in mental clarity

• 15.6% decrease in pain.

Improvement began in the first week of treatment, and continued to increase at the end of the 3 weeks of treatment. The D-ribose was well tolerated.

Conclusions: In this multicenter study, D-ribose resulted in markedly improved energy levels, sleep, mental clarity, pain relief, and well being in patients suffering from fibromyalgia and chronic fatigue syndrome. # NCT01108549.

Source: The Open Pain Journal, June 27, 2012; vol 5, 32-37. Kona Research Center, Kailua Kona, Hawaii; Fibromyalgia and Fatigue Centers, Addison, Texas; Schwabe North America, Lehi, Utah, USA. [Email:]

Post a Comment

Featured Products From the ProHealth Store
Optimized Curcumin Longvida® Guaifenesin FA™ B-12 Extreme™

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products

Article Comments

Be the first to comment on this article!

Post a Comment

Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Subscribe Now!
Receive up-to-date ME/CFS, Fibromyalgia & Lyme Disease treatment and research news
 Privacy Guaranteed  |  View Archives

Repair Damaged Mitochondria and Reduce Fatigue Up to 45%

Featured Products

Guaifenesin FA™ Guaifenesin FA™
Helps the Body Eliminate Excess Calcium and Phosphates
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Hydroxocobalamin Extreme™ Hydroxocobalamin Extreme™
The B-12 your brain needs for detox & sharpness
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
B-12 Extreme™ B-12 Extreme™
The Most Potent Vitamin B-12 on Earth

Natural Remedies

Magnesium + Malic Acid: One-Two Punch for Pain & Fatigue Magnesium + Malic Acid: One-Two Punch for Pain & Fatigue
Prepare Yourself for Cold & Flu Season Prepare Yourself for Cold & Flu Season
Running on Empty? Fuel Up with NADH Running on Empty? Fuel Up with NADH
The Most Powerful Natural Antioxidant Discovered to Date - Hydroxytyrosol The Most Powerful Natural Antioxidant Discovered to Date - Hydroxytyrosol
Nutrients to Combat the Modern Stress Epidemic Nutrients to Combat the Modern Stress Epidemic

What is Fibromyalgia?
Fibromyalgia Diagnosis
Fibromyalgia Symptoms
Fibromyalgia Causes
Fibromyalgia Treatments
Fibromyalgia Diet
Fibromyalgia Medications
M.E. & CFS
What is M.E./CFS?
M.E./CFS Diagnosis
M.E./CFS Symptoms
M.E./CFS Causes
M.E./CFS Treatments
M.E./CFS Diet
M.E./CFS Medications
What is Lyme Disease?
Lyme Disease Diagnosis
Lyme Disease Symptoms
Lyme Disease Causes
Lyme Disease Treatments
Lyme Disease Diet
Lyme Disease Medications
M.E. & CFS
Lyme Disease
General Health
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing