ProHealth fibromyalgia Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Blood Test for Fibromyalgia: FM/a® Test is Real

An open letter to Eli Lilly and all patients affected by Cymbalta's withdrawal symptoms

The Big Hurt: Second Major Fibromyalgia Drug in a Year Fails

New Device Treats Widespread Fibromyalgia and Lyme-Related Pain

12 bloggers share their best tips for reducing fibromyalgia symptoms

VIDEO: Fibromyalgia Pain Relief Stretching Program: Gentle but Effective

An Immune Disease? Low Dose Naltrexone (LDN) Fibromyalgia Study Suggests FM Has Inflammatory Side

Savor the Summer

Are you “feeling” your feelings? Fibromyalgia and PTSD do not have to be a life sentence.

Back to the Future—the Tragedy of Unrelieved Pain and Suffering

 
Print Page
Email Article

Explaining ME/CFS as immune system’s ‘Pavlov’ response to persistent EBV

  [ 23 votes ]   [ 2 Comments ]
www.ProHealth.com • August 10, 2012


Article:
Can persistent Epstein-Barr virus infection induce chronic fatigue syndrome as a Pavlov reflex of the immune response?
– Source: Journal of Biological Dynamics, Jan 2012 (final version of record online Jul 16, 2012)

By Elena Agliari, et al.

[Note: To view the free full text of this article proposing a unifying theory of the etiology of chronic fatigue syndrome / myalgic encephalomyelitis (ME/CFS), CLICK HERE. The article includes some intriguing, plain-language background sections and some very complex, formula-heavy statistical sections. The ‘Pavlov’ response refers to how physiological responses can become conditioned to occur without the initial stimulus - e.g., Pavlov's dogs salivating at the sound of a bell that once accompanied feeding time.]

Abstract:
Chronic fatigue syndrome is a protracted illness condition (lasting even years) appearing with strong flu symptoms and systemic defiances by the immune system.

• Here, by means of statistical mechanics techniques, we study the most widely accepted picture for its genesis, namely a persistent acute mononucleosis infection,

• And we show how such infection may drive the immune system towards an out-of-equilibrium metastable state displaying chronic activation of both humoral and cellular responses (a state of full inflammation without a direct 'causes-effect' reason).

By exploiting a bridge with a neural scenario, we mirror killer lymphocytes T(K) and B cells to neurons and helper lymphocytes

[Formula: see text] and [Formula: see text] to synapses, hence showing that the immune system may experience the Pavlov conditional reflex phenomenon:

• If the exposition to a stimulus (Epstein-Barr virus antigens) lasts for too long,

• Strong internal correlations among B cells, killer lymphocyte T(K) and T(H) may develop

• Ultimately resulting in a persistent activation even though the stimulus itself is removed.

These outcomes are corroborated by several experimental findings.

Source: Journal of Biological Dynamics, Mar 2012;6(2):740-62 – full text of record online Jul 16, 2012. PMID:22873615, by Agliari E, Barra A, Vidal KG, Guerra F. Dipartimento di Fisica, Università degli Studi di Parma, Parma, Italy. [Email: elena.agliari@fis.unipr.it]





Post a Comment

Featured Products From the ProHealth Store
Guaifenesin FA™ Optimized Curcumin Longvida® B-12 Extreme™

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments Post a Comment

This was disproved in the 1980's
Posted by: spacee
Aug 10, 2012
Dr. Steven Straus was most unhappy for it to be disproved and began cursing when he read
the report.

Yet, I do have hope that we have better testing available in the 21st century. And that some
help for those who need it comes from the testing.
Reply Reply

Good News/Bad News
Posted by: Mikie
Aug 31, 2012
The good news is that if anyone ever finds the mechanism of our immune systems' overreaction to one infection, it may explain how our immune systems overreact to other infections. The bad news is that not everyone with our illnesses had them triggered by the EBV. My own illness was triggered full blown my a mycoplasma infaction. Most of us have had an EBV infection or been exposed to it. It never goes away so it is possible that EBV sets us up for our illnesses; however, I believe there is a genetic factor which might help explain why we overreact to pathogens.

Love, Mikie
Reply Reply
 
NAD+ Ignite with Niagen

Featured Products

Hydroxocobalamin Extreme™ Hydroxocobalamin Extreme™
The B-12 Your Brain Needs for Detox & Sharpness
B-12 Extreme™ B-12 Extreme™
The Most Potent Vitamin B-12 on Earth
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Fibro Freedom™ Fibro Freedom™
Soothes, Strengthens & Revitalizes

Natural Remedies

"It's Not Easy Being Green" - But It Is Healthy
Stop Bacteria With Nature's Antibiotics Stop Bacteria With Nature's Antibiotics
Green Coffee Extract: Unique Obesity Intervention Green Coffee Extract: Unique Obesity Intervention
Natural Support for Mood, Sleep and Mental Focus? L-theanine Natural Support for Mood, Sleep and Mental Focus? L-theanine
The Most Powerful Natural Antioxidant Discovered to Date - Hydroxytyrosol The Most Powerful Natural Antioxidant Discovered to Date - Hydroxytyrosol

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map