ProHealth fibromyalgia Vitamin and Natural Supplement Store and Health
Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help

|
|
|

Trending News

New Restrictions on Painkillers: Tramadol and Hydrocodone

A Fibromyalgia Tale of Two Sisters

Energy-Boosting Fibromyalgia Superfoods

SURVEY RESULTS: Pain Treatments

Small Fiber Neuropathy Fibromyalgia Study Raises Questions

Is Venlafaxine Effective for Treating Fibromyalgia?

Can Online Cognitive Behavioral Therapy Help Fibromyalgia?

Fibromyalgia Associated with Decreased Connectivity Between Pain-Related and Sensorimotor Areas of B...

Increased Sensitivity in Fibromyalgia Not Due to Hypervigilance

The Past, Present and Future of Chronic Pain Treatment

 
Print Page
Email Article

Magnesium intake and risk of colorectal cancer: A meta-analysis of prospective studies – Source: European Journal of Clinical Nutrition, Oct 3, 2012

  [ 4 votes ]   [ Discuss This Article ]
By GC Chen, et al. • www.ProHealth.com • October 16, 2012


[Note: This analysis of 338,979 adults whose relative dietary magnesium intake & health was tracked (8 well-designed prospective studies) found an average 19% reduction in risk of colon cancer among those in the highest-magnesium intake group vs. those with lowest intake, and 6% lower risk for rectal cancer. See the NIH Office of Dietary Supplements Magnesium site for info on dietary sources, RDAs, deficiency risk factors and related health problems.]

Abstract:
Epidemiologic studies have suggested that magnesium intake may be associated with a decreased risk of colorectal cancer (CRC), but the findings have been inconsistent. We aimed to assess this association by conducting a meta-analysis of prospective studies.

We performed a literature search on PubMed database through July 2012 to identify prospective studies of magnesium intake in relation to CRC risk. Reference lists of the retrieved articles were also reviewed. A random-effects model was used to compute the summary risk estimates. Eight prospective studies containing 338,979 participants and 8,000 CRC cases met the inclusion criteria.

The summary relative risk (RR) for the highest vs lowest category of magnesium intake for CRC was 0.89 (95% CI, 0.79-1.00), with little evidence of heterogeneity. Restricting the analysis to six studies that have adjusted for calcium intake yielded a similar result.

For colon and rectal cancer, the pooled RR was 0.81 (95% CI, 0.70-0.93) and 0.94 (95% CI, 0.72-1.24), respectively. [Note: a risk ratio of 1.0 would indicate no difference in average risk; accordingly, the RR of 0.81 indicates a 19% reduction of risk in the highest Mg group.]

In the dose-response analyses, the summary RRs for an increment of magnesium intake of 50mg/day for colorectal, colon and rectal cancer were, respectively, 0.95 (95% CI, 0.89-1.00), 0.93 (95% CI, 0.88-0.99) and 0.93 (95% CI, 0.83-1.04), and there was some evidence of heterogeneity; omitting one study that substantially contributed to the heterogeneity yielded generally similar results, but with low heterogeneity. We detected no indication of publication bias.

On the basis of the findings of this meta-analysis, a higher magnesium intake seems to be associated with a modest reduction in the risk of CRC, in particular, colon cancer.

Source: European Journal of Clinical Nutrition, Oct 3, 2012. PMID:23031849, by Chen GC, Pang Z, Liu QF. Department of Epidemiology, School of Public Health, Soochow University, Suzhou, China.




Please Discuss This Article:   Post a Comment 



[ Be the first to comment on this article ]




 
Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Our FREE
Newsletter
Subscribe Now!
Receive up-to-date ME/CFS & Fibromyalgia treatment and research news
 Privacy Guaranteed  |  View Archives

Save on Vitamins and Supplements

Featured Products

Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Optimized Curcumin Longvida® by ProHealth Optimized Curcumin Longvida® by ProHealth
Supports Cognition, Memory & Overall Health
FibroSleep™ by ProHealth FibroSleep™ by ProHealth
The All-in-One Natural Sleep Aid
Fibro Freedom™ Fibro Freedom™
Soothes, strengthens & revitalizes
B-12 Extreme™ B-12 Extreme™
The Most Potent Vitamin B-12 on Earth

Natural Remedies

Protect Against Sun-Induced Skin Aging From The Inside Out Protect Against Sun-Induced Skin Aging From The Inside Out
Preserving Cognitive Function with Aging Preserving Cognitive Function with Aging
Sleep Like a Baby in Nature's Cradle Sleep Like a Baby in Nature's Cradle
Research Links Green Tea to Weight Loss Research Links Green Tea to Weight Loss
Natural Support for Mood, Sleep and Mental Focus? L-theanine Natural Support for Mood, Sleep and Mental Focus? L-theanine

FIBROMYALGIA RESOURCES
What is Fibromyalgia?
Fibromyalgia 101
Fibromyalgia Symptoms
Fibromyalgia Treatments
| CFS RESOURCES
What is CFS?
ME/CFS 101
ME/CFS Symptoms
ME/CFS Treatments
| FORUMS
Fibromyalgia
ME/CFS
ADVANCED MEDICAL LABS
WHOLESALE  |  AFFILIATES
GUARANTEE
CONTACT US
PRIVACY
RSS
SITE MAP
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing