ProHealth fibromyalgia Vitamin and Natural Supplement Store and Health
Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help

|
|
|

Trending News

Where Fibromyalgia and Chronic Fatigue Syndrome Part Ways (and Where They Don't)

Gastrointestinal Problems in Fibromyalgia

Does Fibromyalgia Diet = Deprivation?

The 2013 Fibromyalgia Alternative Diagnostic Criteria: Interpretation for Patients and Providers

Abnormal Cerebral Blood Flow Affects Cognitive Function in Fibromyalgia

Accepting and Surviving Chronic Illness

Fatigue & Fibro Fog: Could You Have a B-12 Deficiency?

Alzheimer's Drug May Benefit Fibromyalgia Patients

Nerves, Estrogen, Dr. Mikovits and Paradoxes: The INTiDYN Approach to Fibromyalgia and Chronic Fatig...

VIDEO: Healthy Eating and Fibromyalgia

 
Print Page
Email Article

‘Early’ oxidative stress damage in ME/CFS patients ages 15 to 45

  [ 4 votes ]   [ 2 Comments ]
www.ProHealth.com • December 4, 2012


Article:
Lipid and protein oxidation in female patients with chronic fatigue syndrome
- Source: Archives of Medical Science, Nov 9, 2012

By Slavica Tomic, Daniela Maric, et al.

[Note: the free full text of this paper reporting evidence of cell damage caused by oxidative stress in CFS patients in “an otherwise low-risk group,” ages 15 to 45, can be found HERE. A series of studies suggest that CFS may be caused in part by oxidative stress, according to Benjamin H Natelson, MD, a leading fatigue researcher now recruiting for a study of its possible impact on brain chemicals in CFS.]

Abstract:
Introduction: Chronic fatigue syndrome (CFS) is a widely recognized problem, characterized by prolonged, debilitating fatigue and a characteristic group of accompanying symptoms, that occurs four times more frequently in women than in men. The aim of the study was to determine the existence of oxidative stress and its possible consequences in female patients with CFS.

Material and methods: Twenty-four women aged 15-45 who fulfilled the diagnostic criteria for CFS with no comorbidities were recruited and were age matched to a control group of 19 healthy women.

After conducting the routine laboratory tests, levels of the lipid oxidation product malondialdehyde (MDA) and protein oxidation protein carbonyl (CO) were determined.

Results: The CFS group had higher levels of triglycerides (p = 0.03), MDA (p = 0.03) and CO (p = 0.002) and lower levels of HDL cholesterol (p = 0.001) than the control group.

There were no significant differences in the levels of total protein, total cholesterol or LDL cholesterol.

Conclusions:

The CFS group had an unfavorable lipid profile and signs of oxidative stress induced damage to lipids and proteins.

These results might be indicative of early proatherogenic processes in this group of patients who are otherwise at low risk for atherosclerosis.

Antioxidant treatment and life style changes are indicated for women with CFS, as well as closer observation in order to assess the degree of atherosclerosis.

Source: Archives of Medical Science, Nov 9, 2012. DOI:10.5114/aoms.2012.31620, by Tomic S, Brkic S, Maric D, Mikic AN. Clinic for Infectious Diseases and Clinic for Gynecology and Obstetrics, Clinical Center Vojvodina, Novi Sad, Serbia. [Email: dijetinfo@gmail.com]




Please Discuss This Article:   Post a Comment 

what type of supplements are they recommending for this issue?
Posted by: Ly45nn
Dec 6, 2012
what type of supplements are they recommending for this issue? What should I ask my doctor about this regarding tests?
Reply Reply

 
oxidative stress
Posted by: IanH
Dec 8, 2012
Oxidative stress induces low grade inflammation. (an immune inflammatory response). Since many people with ME have tested positive for mitochondrial dysfunction and glutathione depletion some correction of these problems can help. (look up these topics on PH, there is plenty of info. )In addition the lipid profile can be improved by supplementing with carnitine or acetyl carnitine. That is, if you can tolerate the carnitine.

One of the best low grade anti-inflammatory regimes is:
curcuminoids
glucosamine/chondroitin
EPA/DHA 5:1 (omega 3 fatty acids in this ratio)
vitamin D3 5000IU
Magnesium chelate (citrate, glycinate, taurinate or other)

 

 
Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Our FREE
Newsletter
Subscribe Now!
Receive up-to-date ME/CFS & Fibromyalgia treatment and research news
 Privacy Guaranteed  |  View Archives

Save on Vitamin B-12

Featured Products

Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
FibroSleep™ by ProHealth FibroSleep™ by ProHealth
The All-in-One Natural Sleep Aid
B-12 Extreme™ B-12 Extreme™
The Most Potent Vitamin B-12 on Earth
Fibro Freedom™ Fibro Freedom™
Soothes, strengthens & revitalizes
Optimized Curcumin Longvida® by ProHealth Optimized Curcumin Longvida® by ProHealth
Supports Cognition, Memory & Overall Health

Natural Remedies

Undenatured Type II Collagen - Chicken Soup for Your Joints Undenatured Type II Collagen - Chicken Soup for Your Joints
Sunshine Vitamin Has D-lightful Health Benefits Sunshine Vitamin Has D-lightful Health Benefits
Running on Empty? Fuel Up with NADH Running on Empty? Fuel Up with NADH
"It's Not Easy Being Green" - But It Is Healthy
Reversing Neurodegeneration with a New Magnesium Compound Reversing Neurodegeneration with a New Magnesium Compound

FIBROMYALGIA RESOURCES
What is Fibromyalgia?
Fibromyalgia 101
Fibromyalgia Symptoms
Fibromyalgia Treatments
| CFS RESOURCES
What is CFS?
ME/CFS 101
ME/CFS Symptoms
ME/CFS Treatments
| FORUMS
Fibromyalgia
ME/CFS
ADVANCED MEDICAL LABS
WHOLESALE  |  AFFILIATES
GUARANTEE
CONTACT US
PRIVACY
RSS
SITE MAP
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing