Activate Now
 
ProHealth fibromyalgia Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Fibromyalgia: The body holding on to past trauma

10 Fast Facts: Fibromyalgia Is Real

Ten Tips to Simplify, Lower the Cost, and Optimize CFS and fibromyalgia Treatment

Top 10 Mood-Boosting Foods for Fibromyalgia

Patient Insights into the Design of Technology to Support a Strengths-Based Approach to Health Care.

3 Genetic Reset Methods Your Doctor Should Prescribe for Fibromyalgia

How to Obtain Relief for Fibromyalgia - Part 1: Complementary and Alternative Therapies

Keep Learning – Even From Bed!

Fibromyalgia Is Correlated with Retinal Nerve Fiber Layer Thinning.

Why You Should Make Your Pleasure a Top Priority

 
Print Page
Email Article

Cymbalta vs. Lyrica: Medical Costs and Medication Compliance Among Fibromyalgia Patients

  [ 3 votes ]   [ Discuss This Article ]
www.ProHealth.com • March 26, 2013


Editor's Note: This study compares both total medical costs and medication compliance among fibromyalgia patients who began taking either duloxetine (Cymbalta) or pregabalin (Lyrica) during the year 2008.  At that time, milnacipran (Savella) had not yet been approved for treating FM. 

Direct Medical Costs and Medication Compliance among Fibromyalgia Patients: Duloxetine Initiators vs. Pregabalin Initiators.
– Source: Pain Practice, March 14, 2013

By P. Sun, et al.

Abstract:

OBJECTIVES: To assess and compare direct medical costs and medication compliance between patients with fibromyalgia who initiated duloxetine and patients with fibromyalgia who initiated pregabalin in 2008.

METHODS:
A retrospective cohort study design was used based on a large US national commercial claims database (2006 to 2009). Patients with fibromyalgia aged 18 to 64 who initiated duloxetine or pregabalin in 2008 and who had continuous health insurance 1 year preceding and 1 year following the initiation were selected into duloxetine cohort or pregabalin cohort based on their initiated agent.

Medication compliance was measured by total supply days, medication possession ratio (MPR), and proportion of patients with MPR  ?  0.8. Direct medical costs were measured by annual costs per patient and compared between the cohorts in the year following the initiation. Propensity score stratification and bootstrapping methods were used to adjust for distribution bias, as well as cross-cohort differences in demographic, clinical and economic characteristics, and medication history prior to the initiation.

RESULTS: Both the duloxetine (n  =  3,033) and pregabalin (n  =  4,838) cohorts had a mean initiation age around 49  years, 89% were women.

During the postindex year, compared to the pregabalin cohort, the duloxetine cohort had

  • higher totally annual supply days (273.5 vs. 176.6, P  <  0.05),

  • higher MPR (0.7 vs. 0.5, P  <  0.05),

  • and more patients with MPR  ?  0.8 (45.1% vs. 29.4%, P  <  0.05).

Further, relative to pregabalin cohort, duloxetine cohort had

  • lower inpatient costs ($2,994.9 vs. $4,949.6, P  <  0.05),

  • lower outpatient costs ($8,259.6 vs. $10,312.2, P  <  0.05),

  • similar medication costs ($5,214.6 vs. $5,290.8, P  >  0.05),

  • and lower total medical costs ($16,469.1 vs. $20,552.6, P  <  0.05) in the postinitiation year.

CONCLUSIONS: In a real-world setting, patients with fibromyalgia who initiated duloxetine in 2008 had better medication compliance and consumed less inpatient, outpatient, and total medical costs than those who initiated pregabalin.


Source: Pain Practice, March 14, 2013. By P. Sun, X. Peng, S. Sun, D. Novick, D.E. Faries, J.S. Andrews, M.M. Wohlreich, and A. Wu. Kailo Research Group, Indianapolis, IN, U.S.A.





Post a Comment

Featured Products From the ProHealth Store
Fibro Freedom™ FibroSleep™ Guaifenesin FA™

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
Natural Pain Relief Supplements

Featured Products

Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
B-12 Extreme™ B-12 Extreme™
The Most Potent Vitamin B-12 on Earth
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Fibro Freedom™ Fibro Freedom™
Soothes, Strengthens & Revitalizes

Natural Remedies

"It's Not Easy Being Green" - But It Is Healthy
Front Line Defense Against Colds & Flu - Support for Healthy Immune System Balance Front Line Defense Against Colds & Flu - Support for Healthy Immune System Balance
IBS, Crohn’s Disease, Colitis, and Other Digestive Disorders IBS, Crohn’s Disease, Colitis, and Other Digestive Disorders
The Guaifenesin Story: A centuries-old bark extract used for clearing the airways – now key to a popular FM symptom-reversal protocol The Guaifenesin Story: A centuries-old bark extract used for clearing the airways – now key to a popular FM symptom-reversal protocol
Cocoa's Polyphenol Riches - All the Health Benefits without the Sugar, Calories or Guilt Cocoa's Polyphenol Riches - All the Health Benefits without the Sugar, Calories or Guilt

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE AND SAVE 15% NOW*
Be the first to know about new products, special discounts and the latest health news. *New subscribers only

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2016 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map