ProHealth fibromyalgia Vitamin and Natural Supplement Store and Health
Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help

|
|
|

Trending News

10 "Healthy" Foods That Are NOT Fibro-Friendly

VIDEO: What It Feels Like To Live With Fibro

Fibromyalgia “Is All in Your Head” and Other Abusive Nonsense

Could Cancer Research Improve the Treatment of Widespread Pain in Fibromyalgia and ME/CFS?

SURVEY: Patient Experience with Physicians

VIDEO: Treating Fibromyalgia with Oxytocin

Fibromyalgia Research Update from Integrated Tissue Dynamics

The Brain Boosting and Fatigue Fighting B-12

Fibromyalgia, Family and Friends: 8 Ways to Improve Relationships

Fibromyalgia Treatment for Older Patients Is Suboptimal

 
Print Page
Email Article

Creatine Supplementation Improved Muscle Function in Fibromyalgia

  [ 1 vote ]   [ 4 Comments ]
www.ProHealth.com • April 8, 2013


Editor's Note: Creatine is a nitrogen-containing organic acid produced in the body from amino acids.  It supports muscle function by working as a reserve energy supply in muscle cells and helping to maintain adenosine triphosphate (ATP) levels.  Muscular contractions are powered by the breakdown of ATP to ADP (adenosine diphosphate). When all the ATP is broken down, creatine phosphate in a muscle donates a phosphate group to ADP and rebuilds ATP, thus promoting further energy reactions.

Article:

Creatine supplementation in fibromyalgia: A double-blind, randomized, placebo-controlled trial.
– Source: Arthritis Care & Research, April 1, 2013

By Christiano R. R. Alves, et al.

Abstract:

OBJECTIVE: To investigate the efficacy and safety of creatine supplementation in fibromyalgia patients.

METHODS: A 16-week, double-blind, randomized, parallel-group, placebo-controlled trial was conducted. Fibromyalgia patients were randomly assigned to receive either creatine monohydrate or placebo in a double-blind fashion. The patients were evaluated at baseline and after 16 weeks. Muscle function, aerobic conditioning, cognitive function, quality of sleep, quality of life, kidney function, and adverse events were assessed. Muscle phosphorylcreatine content was measured through phosphorus magnetic resonance spectroscopy.

RESULTS: After the intervention,

  • the creatine group presented higher muscle phosphorylcreatine content when compared with the placebo group (+80.3% vs. -2.7%, respectively; p = 0.04).

  • Furthermore, the creatine group presented greater muscle strength than the placebo group in the leg-press and chest-press exercises (creatine: +9.8% and +1.2% vs. placebo: -0.5% and -7.2%, respectively; p = 0.02 and p = 0.002).

  • Isometric strength was greater in the creatine group than in the placebo group (+6.4% and -3.2%, respectively, p = 0.007).

  • However, no general changes were observed in aerobic conditioning, pain, cognitive function, quality of sleep, and quality of life.

  • Food intake remained unaltered and no side effects were reported.

CONCLUSION: Creatine supplementation increased intramuscular phosphorylcreatine content and improved lower- and upper-body muscle function, with minor changes in other fibromyalgia features. These findings introduce creatine supplementation as a useful dietary intervention to improve muscle function in fibromyalgia patients.


Source:
Arthritis Care & Research, April 1, 2013. By Christiano R. R. Alves, Bianca M. Santiago, Fernanda R. Lima, Maria C. G. Otaduy, Ana Luisa Calich, Aline C. C. Tritto, Ana Lúcia de Sá Pinto, Hamilton Roschel, Cláudia C. Leite, Fabiana B. Benatti, Eloisa Bonfa and Bruno Gualano. University of Sao Paulo, School of Physical Education and Sports, Rua Professor Mello Moraes, 65 - Sao Paulo - SP - Brazil.





Join the Discussion Post a Comment 


great
Posted by: roge
Apr 8, 2013
so no change in pain , sleep quality and quality of life so what use is their in creatine supplementation then - another useless study
Reply Reply

 
also
Posted by: neoplus1
Apr 8, 2013
No mention about fatigue either.

 

 
strength
Posted by: roge
Apr 8, 2013
ok yes some increased strength but that is not the main issue of those with fm - our strength for the most is ok, it is the PAIN that we get after using our muscles and tendons and again the study said pain was not changed so again this study really has little to no beneft

 


Contraindications
Posted by: Kelly Latta
Apr 9, 2013
Patients need to check with their physician before adding this supplement.

Because many patients take far too many NSAIDS in an effort to control their pain they may be at risk for kidney disease. Kidney disease is asymptomatic until it is too late to save the patient and creatine is not recommended for such patients. If you take NSAIDS often make sure a test is done on kidney function before starting this supplement. Patients with diabetes may also be at risk.

As for who it works for it is quite possible there are subgroups of fibromyalgia patients which scientists have yet to find markers for - and like other forms of arthritis the same treatments do not work for every kind of arthritis. As well, not all creatine supplements are of equal quality and some may not have the amount of ingredient claimed. If one brand doesn't work for you, you may wish to try another before concluding that the supplement does not work for a you.
Reply Reply
 
Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Our FREE
Newsletter
Subscribe Now!
Receive up-to-date ME/CFS & Fibromyalgia treatment and research news
 Privacy Guaranteed  |  View Archives

Save on Your Next Order

Featured Products

Guaifenesin FA™ Guaifenesin FA™
Natural Expectorant Relieves Chest Congestion
Hydroxocobalamin Extreme™ Hydroxocobalamin Extreme™
The B-12 your brain needs for detox & sharpness
Fibro Freedom™ Fibro Freedom™
Soothes, strengthens & revitalizes
FibroSleep™ by ProHealth FibroSleep™ by ProHealth
The All-in-One Natural Sleep Aid
Optimized Curcumin Longvida® by ProHealth Optimized Curcumin Longvida® by ProHealth
Supports Cognition, Memory & Overall Health

Natural Remedies

IBS, Crohn’s Disease, Colitis, and Other Digestive Disorders IBS, Crohn’s Disease, Colitis, and Other Digestive Disorders
Protect Against Sun-Induced Skin Aging From The Inside Out Protect Against Sun-Induced Skin Aging From The Inside Out
The Big Blue Fish that Helps Chase the Blues Away The Big Blue Fish that Helps Chase the Blues Away
Undenatured Type II Collagen - Chicken Soup for Your Joints Undenatured Type II Collagen - Chicken Soup for Your Joints
The Remarkable Benefits of Reishi Medicinal Mushrooms The Remarkable Benefits of Reishi Medicinal Mushrooms

FIBROMYALGIA RESOURCES
What is Fibromyalgia?
Fibromyalgia 101
Fibromyalgia Symptoms
Fibromyalgia Treatments
| CFS RESOURCES
What is CFS?
ME/CFS 101
ME/CFS Symptoms
ME/CFS Treatments
| FORUMS
Fibromyalgia
ME/CFS
ADVANCED MEDICAL LABS
WHOLESALE  |  AFFILIATES
GUARANTEE
CONTACT US
PRIVACY
RSS
SITE MAP
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing