ProHealth fibromyalgia Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Tired of Your Every Night 2 AM Wake-Up Call?

Muscle Trigger Points and Pressure Pain Sensitivity Maps of the Feet in Women with Fibromyalgia Synd...

The Challenges of Being a Sick Parent

Unique fibromyalgia brain signature could eventually lead to easier diagnosis

Benzodiazepines Pose Threat to People Using Opioid Painkillers

How to be Broke and Medicated with Fibromyalgia or ME/CFS

How Not to Treat Brain Fog

What Chronic Illness Has Taught Me About Love

Snooze News – The conundrum of sleep deprivation

Fibromyalgia and Cancer Related Fatigue

 
Print Page
Email Article

Enhanced Glutathione Levels in Blood and Buccal Cells by Oral Glutathione Supplementation

  [ 8 votes ]   [ Discuss This Article ]
By John P Richie et al. • www.ProHealth.com • June 20, 2013


By John P Richie et al.

Abstract

Glutathione (GSH) is the major antioxidant in nearly all cells and plays numerous roles in protection against diseases and biological insults. Previous studies in laboratory animals indicate that orally administered GSH is bioavailable and effective at enhancing tissue GSH levels. The current objective was to determine the efficacy of GSH supplementation at enhancing body stores of GSH in healthy adults.

We conducted a 6-mo randomized, double-blind, placebo controlled trial to determine the impact of GSH administration at 250 mg/day and 1000 mg/day on GSH levels in different blood components and exfoliated buccal mucosal cells. Subjects were 54 healthy adults (41 females/13 males), 28–72 yr of age (mean=46.6 yr). Compliance was >90% by pill count.

After 6 mo in the high dose group, GSH levels were increased 30–35% in RBC, plasma, and lymphocytes and 260% in buccal cells (P<0.05). In most cases, the increases were dose and time dependent and levels returned to baseline after a 1-month washout. No significant changes were observed in levels of protein bound GSH.

A battery of immune function markers was also examined after 3 mo of GSH supplementation and Natural Killer (NK) cytotoxicity was enhanced > 2-fold in the high dose group (P<0.05). Altogether, these findings are consistent with previous pre-clinical studies and indicate that long-term oral administration GSH is an effective means of enhancing body stores of GSH.

Source: The FASEB Journal. 2013;27:862.32. John P Richie, Sailnendra Nichenametla, Ana Calcagnotto, Wanda Neidig, Todd Schell, and Joshua E Muscat





Post a Comment

Featured Products From the ProHealth Store
FibroSleep™ Optimized Curcumin Longvida® Energy NADH™ 12.5mg

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
NAD+ Ignite with Niagen

Featured Products

FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Hydroxocobalamin Extreme™ Hydroxocobalamin Extreme™
The B-12 Your Brain Needs for Detox & Sharpness
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Guaifenesin FA™ Guaifenesin FA™
Helps the Body Eliminate Excess Calcium and Phosphates

Natural Remedies

Restore Youthful Cognition and Well-Being Restore Youthful Cognition and Well-Being
The Brain Boosting and Fatigue Fighting B-12 The Brain Boosting and Fatigue Fighting B-12
Red Yeast Rice - Natural Option for Supporting Healthy Cholesterol Red Yeast Rice - Natural Option for Supporting Healthy Cholesterol
Coping When Colds or Flu Catch Up with You Coping When Colds or Flu Catch Up with You
Natural Bladder Control, Go Less and Live More Natural Bladder Control, Go Less and Live More

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map