ProHealth fibromyalgia Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Lady Gaga Documentary Reveals the Severity of Her Fibromyalgia Pain

VIDEO: Fibromyalgia is Real - A Video for Nonbelievers

Unravelling the Mysteries of ME/CFS and Fibromyalgia: Meet the Man Behind the Book

Is the Fibro-fog in Fibromyalgia a Prelude to Dementia?

An Overlooked Issue in Fibromyalgia? Study Highlights Problems Standing (Orthostatic Intolerance)

Why Lady Gaga having fibromyalgia is both a blessing and curse for the fibromyalgia community

How Myofascial Release Got Me Back On My Feet Again

Born this Way – Me & Lady Gaga

Lymphatic Massage, Clogged Drains and Fibromyalgia Pain

Fibromyalgia Fare Fit for All Seasons

 
Print Page
Email Article

Fibromyalgia Drug Savella May Also Help Prevent Migraines

  [ 4 votes ]   [ 1 Comment ]
www.ProHealth.com • October 25, 2013


Editor's Comment:  Savella (milnacipran), an antidepressant, was the third drug to receive FDA approval for the treatment of fibromyalgia.  In this pilot study, researchers tested the effectiveness of milnacipran for reducing the frequency of episodic or chronic migraines.  Since a significant number of people with fibromyalgia also have migraines, a drug that could do double duty would be a plus. 

A prospective, open-label study of milnacipran in the prevention of headache in patients with episodic or chronic migraine.

By Emily Rubenstein Engel, David Kudrow and Alan M. Rapoport

Abstract:

Migraine is a highly prevalent episodic and chronic neurological disorder that impacts otherwise healthy men and women in their most productive years. An anecdotal survey in our clinical practices suggested that milnacipran, a drug indicated for the treatment of fibromyalgia, reduced the incidence of headache in patients with migraine.

In this 3-month, open-label, pilot study, 38 patients diagnosed with episodic migraine and 7 patients with chronic migraine maintained headache diaries to assess the effectiveness and tolerability of milnacipran in headache prevention. After a 1-month period to obtain baseline data, milnacipran treatment was initiated and doses were titrated up to 100  mg/day over 1  month. Maintenance therapy continued for an additional 3  months. The primary efficacy end point was change from baseline in the number of all headache days during the last 28  days of maintenance therapy analyzed, using last observation carried forward (LOCF). Change from baseline in migraine days during the last month of the maintenance period using LOCF was a secondary end point.

Milnacipran 100  mg daily was associated with a significant reduction in headache (-4.2  days; P  <  0.001) and migraine frequency (-2.2  days; P  <  0.003). The adverse event profile was consistent with prior reports of milnacipran for the treatment of other conditions. However, compared with the recommended protocol, a more gradual increase in milnacipran dose was required to improve tolerability for some patients.

The robust efficacy signal found in this study strongly suggests that a double-blind, placebo-controlled trial of milnacipran in migraine and chronic headache is warranted.

Source: Neurological Sciences, September 2013. By Emily Rubenstein Engel, David Kudrow and Alan M. Rapoport.  Dalessio Headache Center, Scripps Clinic, 10666 North Torrey Pines Rd. MS 313, La Jolla, CA, 92037, USA.





Post a Comment

Featured Products From the ProHealth Store
Guaifenesin FA™ Optimized Curcumin Longvida® FibroSleep™


Article Comments Post a Comment

Ginger helps HypoGal with Pain
Posted by: HypoGal
Oct 28, 2013
I have tried numerous medications to stop the Fibro pain. Unfortunately, I have not found the correct combo. I have tried Savella but the medication was not successful for me.
I believe my Fibro is link to inflammation in my body. I also believe my Fibro is secondary. I was stricken with Fibro after I developed Sheehan's Syndrome.
I have been eating about a half cup of raw ginger daily. I have found that ginger has helped with my pain from Relapsing Polychondritis.
I hope Savella can help others with Fibro
Reply Reply
 
Optimized Curcumin Longvida with Omega-3

Featured Products

Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Guaifenesin FA™ Guaifenesin FA™
Helps the Body Eliminate Excess Calcium and Phosphates
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
B-12 Extreme™ B-12 Extreme™
The Most Potent Vitamin B-12 on Earth

Natural Remedies

Optimize Your Immune System Naturally: Thymic Protein A Optimize Your Immune System Naturally: Thymic Protein A
Prepare Yourself for Cold & Flu Season Prepare Yourself for Cold & Flu Season
Inflammation Disrupts Memory - What Can You Do to Protect Your Brain? Inflammation Disrupts Memory - What Can You Do to Protect Your Brain?
Vital Molecule Increases Cellular Energy and Improves Cognitive Function Vital Molecule Increases Cellular Energy and Improves Cognitive Function
Front Line Defense Against Colds & Flu - Support for Healthy Immune System Balance Front Line Defense Against Colds & Flu - Support for Healthy Immune System Balance

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map