ProHealth fibromyalgia Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help

|
|
|

Trending News

Is Fibromyalgia a Mitochondrial Disorder?

3 Levels of Fibromyalgia Limitations

Significant Mitochondrial Dysfunction Found in Skin of Fibromyalgia Patients

Lyrica Fails as Treatment for Adolescents with Fibromyalgia

Why Paleo for Fibro?

Aortic Elasticity Impaired in Severe Fibromyalgia

Fibromyalgia Patients at Greater Risk for IBS

The Importance of Forgiveness When Living with Chronic Illness

Ask the Doctor: Can fibromyalgia affect your breathing and lungs?

SURVEY RESULTS: Vitamin B12

 
Print Page
Email Article

Update on laser-evoked potential findings in fibromyalgia patients in light of clinical and skin biopsy features.

  [ 1 vote ]   [ Discuss This Article ]
By By Marina de Tommaso, et al. • www.ProHealth.com • January 11, 2014


Abstract:

In fibromyalgia (FM), reduced habituation of laser-evoked potentials (LEPs) suggests a dysfunction of pain processing at a central level. In this study, we aimed to further examine the nociceptive pathways at the peripheral to the central level in a large group of FM patients by means of LEPs and skin biopsy, in light of healthy controls findings and main clinical features.

One hundred and ninety-nine FM patients and 109 age- and sex-matched controls were submitted to LEPs by the dorsum of the right hand and the skin over the right chest and knee tender point stimulation. Skin biopsy was performed in 21 randomly selected FM patients and 60 age- and sex-matched controls.
  • The mean N2-P2 amplitude was reduced in the whole FM group, with normal or even increased values in patients with migraine as comorbidity and reduced values in other patients including those presenting with distal sensory deficits.

  • All patients had reduced N2-P2 habituation in respect to controls.

  • In the FM group, LEPs habituation was correlated with pain at tender points and bad quality of life.

  • Epidermal fiber density was significantly reduced in FM patients versus controls, and correlated with N2-P2 amplitude by the hand and chest tender-point stimulation.

Dysfunction in the nociceptive system at both the central and peripheral levels may concur to explain phenotypical eterogeneity and clinical symptom complexity in fibromyalgia.

Source: Journal of Neurology, December 24, 2013. By Marina de Tommaso, Maria Nolano, Florenzo Iannone, Eleonora Vecchio, Katia Ricci, Marta Lorenzo, Marianna Delussi, Francesco Girolamo, Vito Lavolpe, Vincenzo Provitera, Annamaria Stancanelli, Giovanni Lapadula and Paolo Livrea.



Please Discuss This Article:   Post a Comment 



[ Be the first to comment on this article ]




 
Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Our FREE
Newsletter
Subscribe Now!
Receive up-to-date ME/CFS & Fibromyalgia treatment and research news
 Privacy Guaranteed  |  View Archives

Save on Vitamins and Supplements

Featured Products

Guaifenesin FA™ Guaifenesin FA™
Natural Expectorant Relieves Chest Congestion
Fibro Freedom™ Fibro Freedom™
Soothes, strengthens & revitalizes
B-12 Extreme™ B-12 Extreme™
The Most Potent Vitamin B-12 on Earth
FibroSleep™ by ProHealth FibroSleep™ by ProHealth
The All-in-One Natural Sleep Aid
Hydroxocobalamin Extreme™ Hydroxocobalamin Extreme™
The B-12 your brain needs for detox & sharpness

Natural Remedies

Cocoa's Polyphenol Riches – All the Health Benefits without the Sugar, Calories and Guilt Cocoa's Polyphenol Riches – All the Health Benefits without the Sugar, Calories and Guilt
Running on Empty? Fuel Up with NADH Running on Empty? Fuel Up with NADH
Are You Obtaining the Proper Enzymes? Are You Obtaining the Proper Enzymes?
CoQ10's Role in Fibromyalgia and ME/CFS
Coenzyme Q10 - The Energy Maker Coenzyme Q10 - The Energy Maker

FIBROMYALGIA RESOURCES
What is Fibromyalgia?
Fibromyalgia Diagnosis
Fibromyalgia Symptoms
Fibromyalgia Treatments
| CFS RESOURCES
What is CFS?
ME/CFS Diagnosis
ME/CFS Symptoms
ME/CFS Treatments
| FORUMS
Fibromyalgia
ME/CFS
ADVANCED MEDICAL LABS
WHOLESALE  |  AFFILIATES
GUARANTEE  |  PRIVACY
CONTACT US
LIBRARY
RSS
SITE MAP
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing