ProHealth fibromyalgia Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

The New Me

Eli Lilly Settles Cymbalta Withdrawal Lawsuits

Top Fibromyalgia Drug Tanks: Four Other Drugs On Way

A Genetic Panel for Fibromyalgia? The New Proove Genetic Test

Fibromyalgia Life Lessons - What You Need to Know.

Creating Intimacy Through Mindful Touch When You Live with Chronic Illness

Genes May Be Causing Neuroinflammation and Pain in Fibromyalgia

Pacing through the Perils of Fibromyalgia

3 Fibromyalgia Struggles I’m Glad I Had

The Psychosocial Disease – Has Fibromyalgia Been Captured by a Behavioral Paradigm?

Print Page
Email Article

Important opioid-induced deficiency linked to hot flashes, fatigue, weight gain, depression, more

  [ 72 votes ]   [ 1 Comment ] • July 29, 2012

Opioid-Induced Androgen Deficiency (OPIAD)
– Source: Pain Physician, Jul 2012

By Howard S Smith, MD, Jennifer A Elliott, MD

[Note: The free full text of this article is available HERE.]

Opioid therapy is one of the most effective forms of analgesia currently in use. In the past few decades, the use of opioids as a long-term treatment for chronic pain has increased dramatically.

Accompanying this upsurge in the use of long-term opioid therapy has been an increase in the occurrence of opioid associated endocrinopathy, most commonly manifested as an androgen deficiency and therefore referred to as opioid associated androgen deficiency (OPIAD).

This syndrome is characterized by the presence of inappropriately low levels of gonadotropins (follicle stimulating hormone and luteinizing hormone) leading to inadequate production of sex hormones, particularly testosterone.

Symptoms that may manifest in patients with OPIAD include reduced libido, erectile dysfunction, fatigue, hot flashes, and depression.

Physical findings may include:

• Reduced facial and body hair,

• Anemia,

• Decreased muscle mass,

• Weight gain

• And osteopenia or osteoporosis.

Additionally, both men and women with OPIAD may suffer from infertility.

While the literature regarding OPIAD remains limited, it is apparent that OPIAD is becoming increasingly prevalent among chronic opioid consumers but often goes unrecognized.

OPIAD can have a significant negative impact on the quality of life of opioid users, and clinicians should anticipate the potential for its occurrence whenever long-term opioid prescribing is undertaken.

Once diagnosed, treatment for OPIAD may be offered utilizing a number of androgen replacement therapy options including:

• A variety of testosterone preparations,

• And, for female patients with OPIAD, dehydroepiandrosterone (DHEA) supplementation.

Follow-up evaluation of patients receiving androgen replacement therapy should include a review of any unresolved symptoms of hypogonadism, laboratory evaluation, and surveillance for potential adverse effects of androgen replacement therapy including prostate disease in males.

Source: Pain Physician, Jul 2012;15(3 suppl):ES145-56. PMID:22786453, by Smith HS, Elliott JA. Albany Medical College, Albany, NY; University of Missouri-Kansas City School of Medicine, Kansas City, MO. USA. [Email:]

Post a Comment

Featured Products From the ProHealth Store
B-12 Extreme™ Energy NADH™ 12.5mg Guaifenesin FA™

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products

Article Comments Post a Comment

Usually higher chances of occurances
Posted by: DanielAndersonABS
Aug 6, 2012
Usually higher chances of occurances in men. We should refrain from consuming painkillers.
Reply Reply
Natural Pain Relief Supplements

Featured Products

FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Guaifenesin FA™ Guaifenesin FA™
Helps the Body Eliminate Excess Calcium and Phosphates
Fibro Freedom™ Fibro Freedom™
Soothes, Strengthens & Revitalizes
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function

Natural Remedies

Complete and Natural Menopause Relief Complete and Natural Menopause Relief
Stop Bacteria With Nature's Antibiotics Stop Bacteria With Nature's Antibiotics
Relief for Dry, Itchy Skin Caused by Fibromyalgia Relief for Dry, Itchy Skin Caused by Fibromyalgia
Could a B-12 Deficiency Be Causing Your Symptoms? Could a B-12 Deficiency Be Causing Your Symptoms?
Restore Youthful Cognition and Well-Being Restore Youthful Cognition and Well-Being

ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
Credit Card Processing
Be the first to know about new products, special discounts and the latest health news. *New subscribers only

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2016 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map