ProHealth fibromyalgia Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help

|
|
|

Trending News

Small Fiber Neuropathy Fibromyalgia Study Raises Questions

A Fibromyalgia Tale of Two Sisters

SURVEY: Cognitive Impairment

Magnesium: Widespread Deficiency with Deadly Consequences

Is Venlafaxine Effective for Treating Fibromyalgia?

The Past, Present and Future of Chronic Pain Treatment

Disability Claims and Social Media

Increased Sensitivity in Fibromyalgia Not Due to Hypervigilance

Reduced Intraepidermal Nerve Fiber Density in Skin of Fibromyalgia Patients

Fibromyalgia Associated with Decreased Connectivity Between Pain-Related and Sensorimotor Areas of B...

 
Print Page
Email Article

Abnormal Muscle Membrane Function in Fibromyalgia Patients Correlates with the Number of Tender Points

  [ 67 votes ]   [ 2 Comments ]
www.ProHealth.com • December 3, 2012


Article:

Abnormal muscle membrane function in fibromyalgia patients and its relationship to the number of tender points.
– Source: Clinical and Experimental Rheumatology. November 22, 2012.

By E.G. Klaver-Krol, M.J. Zwarts, et al.

Abstract:

Objectives: Fibromyalgia (FM) is a disorder characterised by chronic widespread pain in soft tissues, especially in muscles. Previous research has demonstrated a higher muscle fibre conduction velocity (CV) in painful muscles of FM patients. The primary goal of this study was to investigate whether there is also a difference in CV in non-painful, non-tender point (TP) related muscles between FM patients and controls. The secondary goal was to explore associations between the CV, the number of TPs and the complaints in FM.

Methods:
Surface electromyography (sEMG) was performed on the biceps brachii muscle of female FM patients (13) and matched healthy controls (13). Short static contractions were applied with the arm unloaded and loaded at 5% and 10% of maximum voluntary force. The CV was derived by cross-correlation method (CV-cc) and inter-peak latency method (CV-ipl). TP score and Fibromyalgia Impact Questionnaire (FIQ) were performed in all participants. Correlations were calculated between the CVs, TP score and items of the FIQ.

Results:
In FM patients, the CV was higher than in the controls (CV-cc p=0.005; CV-ipl p=0.022). The CV was correlated with the number of TPs in FM patients (r=0.642 and 0.672 for CV-cc and CV-ipl, respectively). No correlations were found between the CV and any aspect of health status on the FIQ.

Conclusions:
The results demonstrate abnormally high muscle membrane conduction velocity in FM, even in non-TP muscles. In addition, a relationship has been found between the high membrane velocity and the number of TPs.

Source: Clinical and Experimental Rheumatology. November 22, 2012. By E.G. Klaer-Krol, M.J. Zwarts, P.M. Ten Klooster, and J.J. Rasker. Department of Neurology and Clinical Neurophysiology, Functie Afdeling, Hospital Group Twente ZGT, Hengelo, The Netherlands. E-mail: eklaver@planet.nl.




Please Discuss This Article:   Post a Comment 

Interesting, but>>>
Posted by: IanH
Dec 3, 2012
They should have reported the association between the conduction velocity with the muscle fibre diameter because these two are highly correlated. They are also correlated INDEPENDENT of the underlying neuromuscular pathology. I would expect that this would also apply to fibromyalgia.

With a cohort size of 13X13 it could be that the real difference is fibre diameter not the fact that subjects have FM. However it may be that subjects with FM generally have greater muscle fibre diameter in key pain areas. We just don't know.
Reply Reply

yet more evidence of muscle dysfunction
Posted by: roge
Dec 6, 2012
but we have been led to believe there isnt any - bunch of balony - it has been clear for 30 years, there is muscle dysfunction in FM and so glad we are finally seeing research in this area.
Reply Reply
 
Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Our FREE
Newsletter
Subscribe Now!
Receive up-to-date ME/CFS & Fibromyalgia treatment and research news
 Privacy Guaranteed  |  View Archives

Save on Vitamins and Supplements

Featured Products

Fibro Freedom™ Fibro Freedom™
Soothes, strengthens & revitalizes
Optimized Curcumin Longvida® by ProHealth Optimized Curcumin Longvida® by ProHealth
Supports Cognition, Memory & Overall Health
Guaifenesin FA™ Guaifenesin FA™
Natural Expectorant Relieves Chest Congestion
FibroSleep™ by ProHealth FibroSleep™ by ProHealth
The All-in-One Natural Sleep Aid
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function

Natural Remedies

Irritable Bowel Syndrome: Unlocking the Secrets of Peppermint, Acacia and Fennel Irritable Bowel Syndrome: Unlocking the Secrets of Peppermint, Acacia and Fennel
How I Found My Long-Lost Energy How I Found My Long-Lost Energy
Preserving Cognitive Function with Aging Preserving Cognitive Function with Aging
Live Longer: Groundbreaking Research on Omega-3s Live Longer: Groundbreaking Research on Omega-3s
The Revolutionary 'Good Fat' That Promotes Heart, Brain, Bone and Joint Health The Revolutionary 'Good Fat' That Promotes Heart, Brain, Bone and Joint Health

FIBROMYALGIA RESOURCES
What is Fibromyalgia?
Fibromyalgia 101
Fibromyalgia Symptoms
Fibromyalgia Treatments
| CFS RESOURCES
What is CFS?
ME/CFS 101
ME/CFS Symptoms
ME/CFS Treatments
| FORUMS
Fibromyalgia
ME/CFS
ADVANCED MEDICAL LABS
WHOLESALE  |  AFFILIATES
GUARANTEE
CONTACT US
PRIVACY
RSS
SITE MAP
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing