ProHealth fibromyalgia Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Most Effective Treatment for Fibromyalgia Among Least Used Says Report

ACTION ALERT: Telling Your Chronic Pain Story Now is Important

A NEW Form of Magnesium: Can It Help Brain Fog and Fibromyalgia Pain?

Is Emergency Stress Impacting Your Fibromyalgia Body?

Have Doctors Gone Too Far on Exercise for Fibromyalgia?

Where Is Your Journey Taking You?

Meditation, Cortisol, and Fibromyalgia

The Crucial Role CoQ10 Plays in Fibromyalgia and ME/CFS

Dry Needling Plus Physical Therapy: A Major Advance for Fibromyalgia Treatment

Why Fibro Cheaters Prosper

 
Print Page
Email Article

Reduced N-acetylaspartate in Hippocampus of Fibromyalgia Patients

  [ 3 votes ]   [ Discuss This Article ]
www.ProHealth.com • July 17, 2013


Editor's comment: N-acetylaspartate (NAA), the acetylated form of the amino acid aspartate, is the second most abundant metabolite in the human central nervous system, following only the amino acid glutamate.  NAA emits the strongest signal in magnetic resonance spectrograms of the brain.  NAA levels are known to be altered in a large number of central nervous system disorders and are almost always reduced in neurological disorders involving neuronal loss or dysfunction. 

Reduced N-acetylaspartate in the hippocampus in patients with fibromyalgia: A meta-analysis.

By Yuta Aoki, Ryota Inokuchi and Hiroshi Suwa

Abstract:

Fibromyalgia (FM) is a stress-associated syndrome with chronic, widespread pain. Patients with FM also present disturbances of cognition and memory.

As the hippocampus is vulnerable to stress exposure and involved in cognition, memory and pain perception, we hypothesize that the abnormal function of the hippocampus is implicated in the pathophysiology of FM.

N-acetylaspartate (NAA), a metabolite that can be measured using proton magnetic resonance spectroscopy (1H MRS), is recognized as a marker of neuronal structure and function. We performed a systematic review and meta-analysis of 1H MRS studies investigating NAA levels in patients with FM.  A comprehensive literature search through MEDLINE, Embase and Web of Science yielded nine studies; among these nine, four studies met our criteria for inclusion.

A random effect model with 51 patients with FM and 38 controls revealed a significant NAA reduction in the hippocampus. The current meta-analysis suggested a neuronal abnormality in the hippocampus in patients with FM.

Source: Psychiatry Research, July 5, 2013. By Yuta Aoki, Ryota Inokuchi and Hiroshi Suwa. Department of Psychiatry, Tokyo Metropolitan Health and Medical Treatment Corporation, Ebara Hospital, Ota, Tokyo 145-0065, Japan; Department of Emergency Medicine and Critical Care Medicine, The University of Tokyo Hospital, Bunkyou, Tokyo 113-8655, Japan.





Post a Comment

Featured Products From the ProHealth Store
Energy NADH™ 12.5mg B-12 Extreme™ Guaifenesin FA™

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
Dr Axe Bone Broth Proteins

Featured Products

Hydroxocobalamin Extreme™ Hydroxocobalamin Extreme™
The B-12 Your Brain Needs for Detox & Sharpness
Guaifenesin FA™ Guaifenesin FA™
Helps the Body Eliminate Excess Calcium and Phosphates
Fibro Freedom™ Fibro Freedom™
Soothes, Strengthens & Revitalizes
B-12 Extreme™ B-12 Extreme™
The Most Potent Vitamin B-12 on Earth
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function

Natural Remedies

Thyroid Health and Fibromyalgia Thyroid Health and Fibromyalgia
Cell-Charging Compound Gives Steady Energy to Fibromyalgia & Chronic Fatigue Patients Cell-Charging Compound Gives Steady Energy to Fibromyalgia & Chronic Fatigue Patients
Enhance Eyelashes Naturally Enhance Eyelashes Naturally
Magnesium + Malic Acid: One-Two Punch for Pain & Fatigue Magnesium + Malic Acid: One-Two Punch for Pain & Fatigue
Green Coffee Extract: Unique Obesity Intervention Green Coffee Extract: Unique Obesity Intervention

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE AND SAVE 15% NOW*
Be the first to know about new products, special discounts and the latest health news. *New subscribers only

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2016 ProHealth, Inc. All rights reserved. Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map