ProHealth fibromyalgia Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help

|
|
|

Trending News

Cognitive Dysfunction in Fibromyalgia: Slow Access to the Mental Lexicon

Fibromyalgia Flares: A Qualitative Analysis

Basil Essential Oil Has Analgesic Effect on Mice Model of Fibromyalgia

Effects of a Gluten-Free Diet on IBS and Fibromyalgia

10 Timer Tips for Healthy Fibromyalgia Support

NIH Panel Cites Need for Individualized, Patient-Centered Approach to Treat Chronic Pain

Fatigue & Fibro Fog: Could You Have a B-12 Deficiency?

Cognitive Differences Between Men and Women with Fibromyalgia

The Importance of Acceptance

How Does a Functional Restoration Program Affect Fibromyalgia?

 
Print Page
Email Article

Update on laser-evoked potential findings in fibromyalgia patients in light of clinical and skin biopsy features.

  [ 1 vote ]   [ Discuss This Article ]
By By Marina de Tommaso, et al. • www.ProHealth.com • January 11, 2014


Abstract:

In fibromyalgia (FM), reduced habituation of laser-evoked potentials (LEPs) suggests a dysfunction of pain processing at a central level. In this study, we aimed to further examine the nociceptive pathways at the peripheral to the central level in a large group of FM patients by means of LEPs and skin biopsy, in light of healthy controls findings and main clinical features.

One hundred and ninety-nine FM patients and 109 age- and sex-matched controls were submitted to LEPs by the dorsum of the right hand and the skin over the right chest and knee tender point stimulation. Skin biopsy was performed in 21 randomly selected FM patients and 60 age- and sex-matched controls.
  • The mean N2-P2 amplitude was reduced in the whole FM group, with normal or even increased values in patients with migraine as comorbidity and reduced values in other patients including those presenting with distal sensory deficits.

  • All patients had reduced N2-P2 habituation in respect to controls.

  • In the FM group, LEPs habituation was correlated with pain at tender points and bad quality of life.

  • Epidermal fiber density was significantly reduced in FM patients versus controls, and correlated with N2-P2 amplitude by the hand and chest tender-point stimulation.

Dysfunction in the nociceptive system at both the central and peripheral levels may concur to explain phenotypical eterogeneity and clinical symptom complexity in fibromyalgia.

Source: Journal of Neurology, December 24, 2013. By Marina de Tommaso, Maria Nolano, Florenzo Iannone, Eleonora Vecchio, Katia Ricci, Marta Lorenzo, Marianna Delussi, Francesco Girolamo, Vito Lavolpe, Vincenzo Provitera, Annamaria Stancanelli, Giovanni Lapadula and Paolo Livrea.



Please Discuss This Article:   Post a Comment 



[ Be the first to comment on this article ]




 
Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Our FREE
Newsletter
Subscribe Now!
Receive up-to-date ME/CFS & Fibromyalgia treatment and research news
 Privacy Guaranteed  |  View Archives

Save on Vitamins and Supplements

Featured Products

Fibro Freedom™ Fibro Freedom™
Soothes, strengthens & revitalizes
B-12 Extreme™ B-12 Extreme™
The Most Potent Vitamin B-12 on Earth
Guaifenesin FA™ Guaifenesin FA™
Natural Expectorant Relieves Chest Congestion
Hydroxocobalamin Extreme™ Hydroxocobalamin Extreme™
The B-12 your brain needs for detox & sharpness
FibroSleep™ by ProHealth FibroSleep™ by ProHealth
The All-in-One Natural Sleep Aid

Natural Remedies

IBS, Crohn’s Disease, Colitis, and Other Digestive Disorders IBS, Crohn’s Disease, Colitis, and Other Digestive Disorders
Front Line Defense Against Colds & Flu - Support for Healthy Immune System Balance Front Line Defense Against Colds & Flu - Support for Healthy Immune System Balance
Irritable Bowel Syndrome: Unlocking the Secrets of Peppermint, Acacia and Fennel Irritable Bowel Syndrome: Unlocking the Secrets of Peppermint, Acacia and Fennel
Sleep Like a Baby in Nature's Cradle Sleep Like a Baby in Nature's Cradle
The Most Powerful Natural Antioxidant Discovered to Date - Hydroxytyrosol The Most Powerful Natural Antioxidant Discovered to Date - Hydroxytyrosol

FIBROMYALGIA RESOURCES
What is Fibromyalgia?
Fibromyalgia Diagnosis
Fibromyalgia Symptoms
Fibromyalgia Treatments
| CFS RESOURCES
What is CFS?
ME/CFS Diagnosis
ME/CFS Symptoms
ME/CFS Treatments
| FORUMS
Fibromyalgia
ME/CFS
ADVANCED MEDICAL LABS
WHOLESALE  |  AFFILIATES
GUARANTEE  |  PRIVACY
CONTACT US
LIBRARY
RSS
SITE MAP
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing