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Date Type Title
Jul 01, 2008 Article,ClinicalTrial,Events NIH Depression Drug Trials Now Recruiting in 13 States
Male and female patients ages 18 to 75 with chronic and/or recurrent major depression are now being recruited for a trial titled Combining Medications to Enhance Depression Outcomes (CO-MED) - sponsored by the National Institute of Mental Health (NIMH).
Jul 01, 2008 Article,ClinicalTrial,DrugNews,Events UCLA – Trial of drug to improve cognition & function in adults with depression, ages 60 and older (not yet recruiting)
This 16-week NIH-sponsored study in Los Angeles – Effectiveness of Methylphenidate in Improving Cognition and Function in Older Adults with Depression - will recruit patients age 60 and older.
Jun 30, 2008 Article 'Silent strokes' - 10% of apparently healthy midlife people have been injured by them
Exam findings in people who'd had “silent stroke” match the 10-year risk factors for a clinical stroke - underscoring “the importance of current guidelines for the early diagnosis and prevention of hypertension and atherosclerosis and their risk factors."
Jun 30, 2008 Abstract Prevalence and Correlates of Silent Cerebral Infarcts in the Framingham Offspring Study – Source: Stroke, June 26, 2008
MRIs show 1 in 10 apparently healthy people at mid-life has injury from silent strokes. These go unnoted, but are associated with uncontrolled high blood pressure and artery disease, and are risk factors for dementia, clinical strokes, and atrial fibrillation. [Source: Stroke, June 26, 2008]
Jun 29, 2008 Article Adults with type 2 diabetes may experience memory declines immediately after eating unhealthy meal
Amazingly, the acute negative effect on memory of high-fat meals can be offset by taking antioxidant vitamins with the meal - though a healthy diet rich in fruits and vegetables should be first defense.
Jun 29, 2008 Abstract Antioxidant vitamins reduce acute meal-induced memory deficits in adults with type 2 diabetes - Source: Nutrition Research, July 2008
Amazingly, the memory problems that swiftly followed high-fat meals in this study were avoided when subjects took antioxidant vitamins with the meal - presumably because the problems were caused by free radicals. A healthy diet rich in fruits and vegetables is the preferred preventive. [Source: Nutrition Research, July 2008]
Jun 02, 2008 Abstract Efficacy and safety of tarenflurbil in mild to moderate Alzheimer's disease: A randomized phase II trial - Source: The Lancet Neurology, June 2008
In 2-year UK/Canada trial, anti-amyloid (plaque) drug clearly slowed rate of decline in daily function, concentration, memory vs. placebo patients – but only for those diagnosed early with very mild form of illness. Larger phase III trial results may soon clarify potential. Source: The Lancet Neurology, June 2008
May 29, 2008 Article National Institute on Aging Seeking Participants for Alzheimer’s Disease Genetics Studies
The NIA’s National Cell Repository for Alzheimer’s Disease (NCRAD) is seeking families to contribute blood samples for ongoing genetic studies.
May 01, 2008 Abstract Cognitive Behavioral Therapy for Insomnia Enhances Depression Outcome in Patients with Comorbid Major Depressive Disorder and Insomnia - Source: Sleep, Apr 2008
Study provides evidence that augmenting an antidepressant medication with a brief, symptom focused, Cognitive behavioral therapy for insomnia is promising for individuals with depressive disorder and comorbid insomnia in terms of alleviating both depression and insomnia. [Source: Sleep, Apr 2008]
Apr 09, 2008 Abstract B-vitamins reduce plasma levels of beta amyloid – Source: Neurobiology of Aging, Feb 2008
Placebo-controlled trial reports 75% reduced increase of plaque-component AB40 in blood of older men receiving B vitamins - which “may have a role in the prevention of Alzheimer’s disease.” [Source: Neurobiology of Aging, Feb 2008]
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