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Memory and attention problems in children with CFS/ME – Source: Archives of Disease in Childhood, Nov 11, 2008

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By Andrew Haig-Ferguson, et al. • • November 13, 2008

Objective: To understand more about the problems children with CFS/ME experience with their memory and attention, and to test the feasibility of quantitative measurement of both memory and attention.

Design: 4 item semi-structured questionnaire and Neuropsychological test battery with 10 psychometric subtests.

Setting: Family home of the child taking part.

Patients: 20 children with a diagnosis of CFS/ME and experiencing memory and/or concentration problems were recruited between April and October 2007 from a regional CFS/ME clinical service (Female=13; Average age 13.5yrs; Range 8 - 16 yrs).


Each child, parent and teacher was asked to describe the child's memory and attention problems.

Responses were subject to thematic analysis by two independent researchers.

In addition each child completed a battery of 10 tests to measure: Processing speed; Attention; Immediate and Delayed Memory; Working Memory; Executive Function.

Raw scores were converted into age-scaled scores and the children's psychometric scores on the 10 tests taken were compared with normative data using t-tests.

Results: Children with CFS/ME, their parents and teachers described problems with:

• Focused attention,

• Sustained attention,

• Recall and stress.

Children's scores were compared to normative data. Scores for sustained attention (mean 8.1, 95% CI 6.3-9.9), switching attention (7.5, 5.5-9.4), divided attention (6.9, 5.5-8.2), auditory learning (8.2, 6.8-9.6) and immediate recall (8.7, 7.3-10.0) appeared lower than the normative mean of 10.

Conclusions: Children with CFS/ME appear to experience problems with attention, which may have adverse implications for verbal memory. These cognitive problems may explain some of the educational difficulties associated with Chronic Fatigue Syndrome.

Source: Archives of Disease in Childhood, Nov 11, 2008. [E-pub ahead of print] PMID: 19001478, by Haig-Ferguson A, Tucker P, Eaton N, Hunt L, Crawley E. University of Bristol, United Kingdom. [E-mail:]

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