ProHealth health Vitamin and Natural Supplement Store and Health
Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help

|
|
|
|

Trending News

CDC Whistleblower Reveals Widespread Manipulation of Scientific Data and Top-Down Pressure on CDC Sc...

Do gut bacteria rule our minds?

Fatigue & Fibro Fog: Could You Have a B-12 Deficiency?

Irritable Bowel Syndrome: Unlocking the Secrets of Peppermint, Acacia and Fennel

9 Health Benefits of Cucumbers

Preserving Cognitive Function with Aging

Coenzyme Q10 Benefits Symptoms in Gulf War Veterans: Results of a Randomized Double-Blind Study

Antibiotics in early life may alter immunity long-term

Low vitamin D levels linked to increased risks after noncardiac surgery

Depression Linked to Parkinson's Disease

 
Print Page
Email Article

Oxidative stress in fibromyalgia and its relationship to symptoms- Source: Clinical Rheumatology, Dec 17, 2008

  [ 32 votes ]   [ Discuss This Article ]
By Cecilia P Chung, C Michael Stein, et al. • www.ProHealth.com • December 18, 2008


[Note: Oxidative stress/free radical damage to cells results from an imbalance between products of oxidation and antioxidant defenses. The authors note it is increased in patients with ME/CFS.]

Oxidative stress is thought to play a role in the pathogenesis of fibromyalgia. We examined the hypothesis that oxidative stress was increased in patients with fibromyalgia and related to the severity of symptoms.

Urinary F(2)-isoprostane excretion was measured in 48 patients with fibromyalgia and compared to those of 96 control subjects. In patients, we examined the association between oxidative stress and symptoms.

Patients with fibromyalgia were significantly more symptomatic than control subjects, but urinary F(2)-isoprostane excretion did not differ significantly (2.3 +/- 1.9 vs. 2.8 +/- 2.2 ng/mg creatinine, p = 0.16).

In patients with fibromyalgia, F(2)-isoprostane excretion was associated with fatigue visual analog scale (rho = 0.30, p = 0.04) but not with pain, quality of life, functional capacity, depression, number of tender points, or overall impact of fibromyalgia.

Oxidative stress is not increased in patients with fibromyalgia, but as was previously found in patients with systemic lupus erythematosus, oxidative stress was associated with fatigue.

Source: Clinical Rheumatology, Dec 17, 2008. E-pub ahead of print. PMID: 19089486, by Chung CP, Titova D, Oeser A, Randels M, Avalos I, Milne GL, Morrow JD, Stein CM. Department of Medicine, School of Medicine, Vanderbilt University, Nashville, Tennessee, USA. [E-mail: michael.stein@vanderbilt.edu]




Please Discuss This Article:   Post a Comment 



[ Be the first to comment on this article ]




 
Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Our FREE
Newsletter
Subscribe Now!
Receive up-to-date ME/CFS & Fibromyalgia treatment and research news
 Privacy Guaranteed  |  View Archives

Save on Vitamin B-12

Featured Products

Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Optimized Curcumin Longvida® by ProHealth Optimized Curcumin Longvida® by ProHealth
Supports Cognition, Memory & Overall Health
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Vitamin D3 Extreme™ by ProHealth Vitamin D3 Extreme™ by ProHealth
50,000 IU Vitamin D3 - Prescription Strength

Natural Remedies

More Weight Loss than Any Other Discovery in Supplement History More Weight Loss than Any Other Discovery in Supplement History
Running on Empty? Fuel Up with NADH Running on Empty? Fuel Up with NADH
Are You Obtaining the Proper Enzymes? Are You Obtaining the Proper Enzymes?
Sleep Like a Baby in Nature's Cradle Sleep Like a Baby in Nature's Cradle
Research Links Green Tea to Weight Loss Research Links Green Tea to Weight Loss

FIBROMYALGIA RESOURCES
What is Fibromyalgia?
Fibromyalgia 101
Fibromyalgia Symptoms
Fibromyalgia Treatments
| CFS RESOURCES
What is CFS?
ME/CFS 101
ME/CFS Symptoms
ME/CFS Treatments
| FORUMS
Fibromyalgia
ME/CFS
ADVANCED MEDICAL LABS
WHOLESALE  |  AFFILIATES
GUARANTEE
CONTACT US
PRIVACY
RSS
SITE MAP
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing