Activate Now
ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help

Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Brain White Matter Abnormalities in Female Interstitial Cystitis/Bladder Pain Syndrome: A MAPP Netwo...

International Lyme and Associated Diseases Society Hosts Its Annual Scientific Conference in Ft. Lau...

How One LLND Treats Lyme disease and Co-infections Using Natural Medicine

Acupuncture reduces hot flashes in breast cancer survivors

Top 7 Nutrient-Dense Foods That Make Calorie Counting Obsolete

For veterans with Gulf War Illness, an explanation for the unexplainable symptoms

SURVEY: Has Your Illness Affected What You Eat?

DePaul Study Recruiting Participants

VIDEO: Dr. Horowitz Discusses Lyme Disease and Chronic Illness

Cocoa flavanols lower blood pressure and increase blood vessel function in healthy people

Print Page
Email Article

Supplements of 20 micrograms/day cholecalciferol [vitamin D3] optimized serum 25-Hydroxyvitamin D concentrations in 80% of premenopausal women in winter - Source: Journal of Nutrition, March 2009

  [ 6 votes ]   [ Discuss This Article ]
By Monica L Nelson, Susan S Sullivan, et al. • • March 9, 2009

[Note: ug stands for microgram, or one thousanth of a miligram. Most supplements express dosages in international units (iu) – which is an international standard of an agreed upon biological effect. This varies by the substance measured. For vitamin D3, the conversion to iu is ug times 40; so 22 ug/day – the amount given to these young women starting in September - translates to 880 iu/day. Blood testing for 25(OH)D is considered the best indicator of vitamin D status.]

The serum 25-hydroxyvitamin D [25(OH)D] response to daily supplementation with 20 ug cholecalciferol (D3) during winter in predominantly white premenopausal women living in Maine was measured and the effects of body composition and hormonal contraceptive use on baseline serum 25(OH)D concentrations and the response to supplementation were examined.

A total of 112 women (22.2 ± 3.7 years old) received placebo from March 2005 until September 2005 when they were randomized to receive either placebo or 20 ug/d D3 through February 2006. Eighty-six women completed the study.

Actual mean D3 content of the supplements was 22 ug per capsule. In February 2005 the serum 25(OH)D concentration was 62.0 ± 23.4 nmol/L (mean ± SD).

Serum 25(OH)D concentrations increased by 35.3 ± 23.2 nmol/L from February 2005 to February 2006 in the treatment group, significantly more than the 10.9 ± 16.9 nmol/L increase in the placebo group. Treatment group, magnitude of summer increase in 25(OH)D, estrogen dose, and baseline serum 25(OH)D concentrations, but not body fat, were significant predictors of the 1-year change in 25(OH)D concentrations used to assess the magnitude of the response to supplementation.

Daily supplementation with 20 ug D3 during winter achieved optimal 25(OH)D concentrations (75 nmol/L or more) in 80% of participants, indicating that this dose is adequate to optimize vitamin D status in most young women in Maine.

Source: Journal of Nutrition, March 2009;139(3). Nelson ML, Blum JM, Hollis BW, Rosen C, Sullivan SS. University of Maine, Department of Food Science and Human Nutrition, Orono, Maine; Dietary Supplement Research Group, Saco, Maine; Medical University of South Carolina, Department of Pediatrics, Charleston, South Carolina; Maine Medical Center Research Institute, Scarborough, Maine, USA. [E-mail:]

Please Discuss This Article:   Post a Comment 

[ Be the first to comment on this article ]

Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Subscribe Now!
Receive up-to-date ME/CFS, Fibromyalgia & Lyme Disease treatment and research news
 Privacy Guaranteed  |  View Archives

Vitamins and Supplements

Featured Products

Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils

Natural Remedies

Aches and Pains? A Simple Solution You'll Love Aches and Pains? A Simple Solution You'll Love
Vitamin E: Super Antioxidant We Only Thought We Knew Vitamin E: Super Antioxidant We Only Thought We Knew
Eating Fat is Good… Maybe… Could Be… Sometimes Eating Fat is Good… Maybe… Could Be… Sometimes
Research Links Green Tea to Weight Loss Research Links Green Tea to Weight Loss
Energy Breakthrough - One Fibromyalgia Patient’s Fortuitous Discovery Energy Breakthrough - One Fibromyalgia Patient’s Fortuitous Discovery

What is Fibromyalgia?
Fibromyalgia Diagnosis
Fibromyalgia Symptoms
Fibromyalgia Causes
Fibromyalgia Treatments
Fibromyalgia Diet
Fibromyalgia Medications
M.E. & CFS
What is M.E./CFS?
M.E./CFS Diagnosis
M.E./CFS Symptoms
M.E./CFS Causes
M.E./CFS Treatments
M.E./CFS Diet
M.E./CFS Medications
What is Lyme Disease?
Lyme Disease Diagnosis
Lyme Disease Symptoms
Lyme Disease Causes
Lyme Disease Treatments
Lyme Disease Diet
Lyme Disease Medications
M.E. & CFS
Lyme Disease
General Health
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing