ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Fighting Heartburn and Gerd Naturally – And Safely!

Vital Molecule Increases Cellular Energy and Improves Cognitive Function

Natural Bladder Control, Go Less and Live More

Top Vitamin and Mineral Deficiencies — Are You at Risk?

Trimming the spare tire: Canola oil may cut belly fat

How Pomegranate May Protect Against Cancer

Omega Fix for Obesity: How the Right Fats Fight Fat

Curcumin Reverses the Cellular Damage of Chronic Stress

The Onion: Cancer Fighter and Food Preserver

Probiotics improve cognition in Alzheimer's patients

 
Print Page
Email Article

Efficacy and Safety Study of the Experimental Drug Aplindore in Patients With Restless Legs Syndrome – Now Recruiting Across the U.S.

  [ 5 votes ]   [ Discuss This Article ]
www.ProHealth.com • April 17, 2009


24 trial sites in 15 states are recruiting a total of 230 patients with moderate to severe restless legs syndrome for a six-week trial of the controlled release drug aplindore MS.

The trial targets 230 patients, who will be randomly assigned to five groups – four groups taking different dosages of the drug and one group taking a placebo (fake dose).

In a previous phase 2 trial for RLS symptoms, a 0.05 mg “starting dose” of aplindore reportedly achieved “statistically significant efficacy,” possibly indicating the drug may be better tolerated and not require the slow phasing in or titration needed with drugs now prescribed for RLS. As a “dopamine partial agonist,” aplindore activates dopamine receptors, but to a lesser extent than a full dopamine agonist. (The neurotransmitter dopamine has been shown to reduce RLS symptoms. It is responsible for arousal or alertness, by comparison with serotonin, which relaxes.)

• Patients ages 18-85 of both sexes may be eligible for the trial.

• Symptoms must be moderate to severe, disrupting sleep for at least 3 nights per week for a least 3 months,

• And the person must be off dopamine agonists or other meds taken for RLS for a specified period before Day 1 of the trial.

For more information about the trial and locations of the trial sites, and to contact the trial organizers, visit the ClinicalTrials.gov site for Efficacy and safety Study of Aplindore in Patients with Restless Legs Syndrome, Identifier NCT00834327




Post a Comment

Featured Products From the ProHealth Store
Energy NADH™ 12.5mg FibroSleep™ Vitamin D3 Extreme™


Article Comments



Be the first to comment on this article!

Post a Comment


 
Natural Pain Relief Supplements

Featured Products

Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid

Natural Remedies

The Remarkable Benefits of Reishi Medicinal Mushrooms The Remarkable Benefits of Reishi Medicinal Mushrooms
Natural Bladder Control, Go Less and Live More Natural Bladder Control, Go Less and Live More
Quercetin: Natural Support for Allergy & Inflammation Relief and More Quercetin: Natural Support for Allergy & Inflammation Relief and More
Block Acid Reflux to Prevent Esophageal Problems! Block Acid Reflux to Prevent Esophageal Problems!
How I Found My Long-Lost Energy How I Found My Long-Lost Energy

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2016 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map