ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help

|
|
|
|

Trending News

Magnesium: Widespread Deficiency with Deadly Consequences

Gut Bacteria, Artificial Sweeteners and Glucose Intolerance

Reverse Mitochondrial Damage

Strengthening DNA to Prevent Inflammation, Heart Disease, Dementia and More

Culprits of Autism Identified: Toxins, Gut Bacteria, Nutritional Deficiencies, and Vaccines Made wit...

CoQ10: The Longevity Factor

Turmeric compound boosts regeneration of brain stem cells

Use of Broad-Spectrum Antibiotics Before Age 2 Associated with Obesity Risk

Extending Life and Fighting Disease with Resveratrol

Is Homocysteine Making You Sick?

 
Print Page
Email Article

Multiple Sclerosis Trial Alert: Investigators Recruiting 1,260 People with MS for Study of PEGylated Interferon Beta-1a

  [ 3 votes ]   [ Discuss This Article ]
By National Multiple Sclerosis Society • www.ProHealth.com • September 10, 2009


Source: National Multiple Sclerosis Society trial announcement (www.nationalmssociety.org), Aug 31, 2009

Summary: Investigators worldwide are recruiting 1,260 people with relapsing MS for a Phase III clinical trial comparing the effectiveness of BIIB017 (PEGylated interferon beta-1a, delivered under the skin) and inactive placebo. The study is sponsored by Biogen Idec.

Rationale: Avonex® (interferon beta-1a, Biogen Idec) is approved by the U.S. Food and Drug Administration for the treatment of people with relapsing forms of MS to slow the accumulation of physical disability and decrease the frequency of clinical exacerbations. BIIB017 is a “pegylated” form of the interferon beta-1a molecule. PEGylated molecules are attached to a molecule of polyethylene glycol, which enables them to maintain effects in the body for longer periods of time.

This formulation has been tested in healthy individuals in two phase I clinical trials, but has not yet been tested in people with MS. If proven to be safe and effective in treating MS, this drug may help to reduce the frequency of administration of interferon beta and the flu-like side effects that can occur with each treatment.

Eligibility and Details: Investigators are seeking participants aged 18 to 55 who have experienced at least two relapses that have been medically documented within the last three years, with one occurring in the last 12 months.

Participants will be randomly assigned to one of three groups, for a study period of approximately two years and three months:
• Placebo
• BIIB017 125 mg delivered subcutaneously (under the skin) every two weeks
• BIIB017 125 mg delivered subcutaneously every four weeks

The primary objective of the study is to determine the effects of the drug versus placebo on the annualized relapse rate. Secondary objectives include the effects on tissue damage as observed on MRI scans, quality of life, and disease progression as measured by the EDSS scale.

Contact: To learn more about the enrollment criteria for this study, and to find out if you are eligible to participate, please email ADVANCEStudy@biogenidec.com. As of now, sites are located in the following cities in the United States:

Lexington, KY
Dallas, TX
Akron, OH
Raleigh, NC
Franklin, TN
St Petersburg, FL
Atlanta, GA
Round Rock, TX

To download a brochure discussing issues to think about when considering enrolling in an MS clinical trial (PDF), see the trial listing at the National MS Society site.




Please Discuss This Article:   Post a Comment 



[ Be the first to comment on this article ]




 
Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Our FREE
Newsletter
Subscribe Now!
Receive up-to-date ME/CFS & Fibromyalgia treatment and research news
 Privacy Guaranteed  |  View Archives

Save on Vitamins and Supplements

Featured Products

Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
FibroSleep™ by ProHealth FibroSleep™ by ProHealth
The All-in-One Natural Sleep Aid

Natural Remedies

Are You Obtaining the Proper Enzymes? Are You Obtaining the Proper Enzymes?
Broad Spectrum Protection Against Brain Aging Broad Spectrum Protection Against Brain Aging
Natural Support for Mood, Sleep and Mental Focus? L-theanine Natural Support for Mood, Sleep and Mental Focus? L-theanine
Itching to Find Dry Skin Relief? Itching to Find Dry Skin Relief?
The Brain Boosting and Fatigue Fighting B-12 The Brain Boosting and Fatigue Fighting B-12

FIBROMYALGIA RESOURCES
What is Fibromyalgia?
Fibromyalgia 101
Fibromyalgia Symptoms
Fibromyalgia Treatments
| CFS RESOURCES
What is CFS?
ME/CFS 101
ME/CFS Symptoms
ME/CFS Treatments
| FORUMS
Fibromyalgia
ME/CFS
ADVANCED MEDICAL LABS
WHOLESALE  |  AFFILIATES
GUARANTEE
CONTACT US
PRIVACY
RSS
SITE MAP
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing