Activate Now
 
ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

High dose vitamin D3 supplementation lowers inflammatory T cells in multiple sclerosis patients

Chocolate's Potential Health Benefits – and its Effect on Chronic Fatigue Syndrome Patients

Repair Damaged Mitochondria and Reduce Fatigue Up to 45%

Essential Oils - How and Where to Use Them

The Link Between Vitamin C And Optimal Immunity

SURVEY: What Is Your Diagnosis?

Liposomes Deliver Optimal Nutrient Absorption

Why Does Your Nose Run When It's Cold Outside?

What's So Great About Grape Seed?

How Your Mitochondria Influence Your Health

 
Print Page
Email Article

Cardiac Toxicity in Chronic Fatigue Syndrome: Results from a Randomized 40-Week Multicenter Double-blind Placebo Control Trial of Rintatolimod [Ampligen®] – Source: Journal of Applied Research, vol 10, #3, 2010

  [ 9 votes ]   [ Discuss This Article ]
By Bruce C Stouch, et al. • www.ProHealth.com • October 7, 2010


[Note: to read the full text of the article, click HERE]

The sedentary life-style caused by extreme fatigue is a significant risk factor for heart disease, which is a leading cause of death in Chronic Fatigue Syndrome (CFS) patients.

AMP-516, a 40-week double-blind, placebo controlled study in CFS patients to evaluate the effectiveness of rintatolimod (Ampligen®) included repeated QT interval measurements. [Note: The QT interval is the time between the start of the Q wave and end of the T wave in the heart’s electrical cycle (heartbeat) – measured in milliseconds (ms). A prolonged QT interval is thought to be associated with a defect in the heart muscle cell structures called ion channels, which are special pores in the cell membrane that control the passage of ions into and out of the cell as it ‘beats.’]

A 5 [or greater] ms post-treatment mean increase in QT prolongation was observed in the placebo group, while a [less than] 5 ms mean post-treatment increase in QT prolongation was observed in the rintatolimod patients.

A greater proportion of the placebo patients were found to have significant QT prolongation, compared to patients receiving rintatolimod.

The increase in QT in the placebo group was associated with continued use of concomitant medications known to prolong QT: patients randomized to receive rintatolimod were able to significantly reduce their dependence on these same medications. [Note: Drugs not specified, but to review a list of drugs that may have this side effect, click HERE.]

Reducing the risk of cardiac toxicity by reducing fatigue and the use of concomitant medications with serious side effects is an important clinical objective and underscores the seriousness of CFS.

Source: Journal of Applied Research, vol 10, #3, 2010, pp. 80-87. Stouch BC, Strayer D, Carter W. Philadelphia College of Osteopathic Medicine; Hemispherx Biopharma, Inc., Philadelphia, Pennsylvania, USA.





Post a Comment

Featured Products From the ProHealth Store
Vitamin D3 Extreme™ Ultra EPA  - Fish Oil Ultra ATP+, Double Strength

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Our FREE
Newsletter
Subscribe Now!
Receive up-to-date ME/CFS, Fibromyalgia & Lyme Disease treatment and research news
 Privacy Guaranteed  |  View Archives

How Glutathione Can Save Your Life

Featured Products

Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function

Natural Remedies

Vitamin K-2 – A Key Player in Cardiovascular and Bone Health Vitamin K-2 – A Key Player in Cardiovascular and Bone Health
Vitamin E: Super Antioxidant We Only Thought We Knew Vitamin E: Super Antioxidant We Only Thought We Knew
The Brain Boosting and Fatigue Fighting B-12 The Brain Boosting and Fatigue Fighting B-12
Mitochondria-Booster NIAGEN® Shows Promise in First Human Clinical Trial Mitochondria-Booster NIAGEN® Shows Promise in First Human Clinical Trial
Secret Nutrient for Radiant Skin Secret Nutrient for Radiant Skin

FIBROMYALGIA
What is Fibromyalgia?
Fibromyalgia Diagnosis
Fibromyalgia Symptoms
Fibromyalgia Causes
Fibromyalgia Treatments
Fibromyalgia Diet
Fibromyalgia Medications
M.E. & CFS
What is M.E./CFS?
M.E./CFS Diagnosis
M.E./CFS Symptoms
M.E./CFS Causes
M.E./CFS Treatments
M.E./CFS Diet
M.E./CFS Medications
LYME DISEASE
What is Lyme Disease?
Lyme Disease Diagnosis
Lyme Disease Symptoms
Lyme Disease Causes
Lyme Disease Treatments
Lyme Disease Diet
Lyme Disease Medications
FORUMS
Fibromyalgia
M.E. & CFS
Lyme Disease
General Health
WHOLESALE
AFFILIATES GUARANTEE
PRIVACY
CONTACT US
LIBRARY
RSS
SITE MAP
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing