ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Inflammation Disrupts Memory - What Can You Do to Protect Your Brain?

All About Ginkgo Biloba: Benefits of This Timeless Herbal Supplement

Yarrow Oil: Here's Why It Deserves a Place in Your First-Aid Kit

Trial Finds Reduction in Depressive Symptoms Following Magnesium Supplementation

Artificial sweeteners linked to risk of weight gain, heart disease and other health issues

Carnitine deficiency suggested as contributor to autism

Vitamin D supplement use associated with lower risk of breast cancer

Hop Oil: A Safe Sleep Aide

White Camphor Oil: The Purest Camphor Oil

Lutein — An Important Nutrient for Eye and Brain Health

 
Print Page
Email Article

Fish Oil DHA within 5 Hours After Stroke May Limit & Even Repair Some Brain Damage – LSU Research Discovery

  [ 14 votes ]   [ Discuss This Article ]
www.ProHealth.com • November 8, 2010


In these animal trials, “Not only did DHA treatment salvage brain tissue that would have died, its repair mechanisms rendered some areas indistinguishable from normal tissue by 7 days.”

Research led by Dr. Nicolas Bazan, MD, PhD, at Louisiana State University has shown that a component of fish oil - Docosahexaenoic acid (DHA) -  is a powerful therapeutic agent that can protect brain tissue and promote recovery in an experimental model of acute ischemic (blockage-caused) stroke, even when treatment is delayed by up to five hours.

These findings not only target a new stroke treatment approach, but also provide vital information about the length of the therapeutic window.

The NIH-funded research was published Nov 8 by the journal Translational Stroke Research. [See the open access article: “Docosahexaenoic Acid Therapy of Experimental Ischemic Stroke.”]

Ischemic strokes result from loss of blood flow to an area of the brain due to a blockage such as a clot or atherosclerosis.

• The damage includes an irreversibly injured core of tissue at the site of the blockage.

• The area of tissue surrounding the core, called the penumbra, is also damaged but potentially salvageable.

• The penumbra has a limited life span and appears to undergo irreversible damage within a few hours unless blood flow is reestablished and neuroprotective therapy is administered. (A cascade of chemicals floods the tissue along with restored blood flow, including damaging free radicals and pro-inflammatory enzymes which can cause further damage and cell death.)

The DHA in fish oil is an essential omega-3-fatty acid and is vital for proper brain function. It is also necessary for the development of the nervous system, including vision. Moreover, omega-3 fatty acids, found in cold water fatty fish, including salmon, tuna, mackerel, sardines, shellfish, and herring, are part of a healthy diet that helps lower the risk of heart disease. [DHA is also found in krill & algae oils, which is where the fish get it.]

DHA has potent anti-inflammatory effects. Since inflammation is at the root of many chronic diseases, DHA treatment has been widely demonstrated to have beneficial effects in patients with coronary heart disease, asthma, rheumatoid arthritis, osteoporosis, sepsis, cancer, dry eye disease, and age-related macular degeneration, but its potential benefit in stroke was not known.

"We are just now beginning to understand the significant impact of omega-3 essential fatty acids on stroke," notes Dr. Bazan. "There is no simple solution just yet, but each new discovery brings us closer to defeating stroke and other debilitating neurodegenerative diseases."

To determine how DHA might be effective in stroke treatment and recovery, the LSUHSC research team administered either DHA or saline intravenously at 3, 4, 5, and 6 hours after the onset of stroke.

• MRIs showed that neurological deficits were reduced by the administration of DHA.

• DHA treatment reduced swelling and facilitated neurobehavioral recovery.

• The volume of the area of destroyed tissue was reduced by an average of 40% when DHA was administered at 3 hours, 66% at 4 hours, and 59% at 5 hours.

• Further analysis showed it triggered production of Neuroprotectin D1 (NPD1), a naturally occurring neuroprotective molecule in the brain derived from DHA and discovered by Dr. Bazan.

• Not only did DHA treatment salvage brain tissue that would have died, its repair mechanisms rendered some areas indistinguishable from normal tissue by 7 days. Dr. Bazan's laboratory leads the field of medical research into understanding DHA's and NPD1's pro-survival properties.

Administering clot-busting drugs (thrombolysis) is currently the only treatment for ischemic stroke. But due to a narrow therapeutic window and complexity of administration, only 30% of patients benefit from thrombolysis.

According to the World Health Organization, 15 million people worldwide have a stroke each year, 6 million of whom die from it. Stroke is the second leading cause of death for people above the age of 60 and is the leading cause of long-term disability irrespective of age, gender, ethnicity or country. Louisiana ranks 46th in stroke deaths. It has been estimated that the direct and indirect costs of stroke in the United States total nearly $74 billion.

"We are in an unprecedented time, from a public health point of view, in regards to tackling stroke and other neurodegenerative disorders," concludes Dr. Bazan.

"Stroke is an outright attack on the nervous system, and each year stroke kills over 150,000 Americans,” he says. “Truly for the first time, translational research and the clinics are poised to converge in their public health efforts to combat stroke.

“From a therapeutic point of view, we can now see a light at the end of the tunnel. What we need now is for the political and societal views on stroke to converge in the same way that the research laboratories and hospitals are now doing. This would be a major step forward in fighting this disease."

Co-authors include Ludmila Belayev, MD, Larissa Khoutorova, BS, Kristal Atkins, BS, MS, Tiffany N. Eady, LSUHSC MD/PhD student, Song Hong, PhD, and Yan Lu, MD at LSU Health Sciences Center New Orleans, as well as Andre Obenaus, PhD, at Loma Linda University in California.
___
Source: Louisiana State University Health Sciences Center press release, Nov 8, 2010




Post a Comment

Featured Products From the ProHealth Store
Optimized Curcumin Longvida® Ultra EPA  - Fish Oil Ultra ATP+, Double Strength


Article Comments



Be the first to comment on this article!

Post a Comment


 
NAD+ Ignite with Niagen

Featured Products

Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium

Natural Remedies

Optimize Your Immune System Naturally: Thymic Protein A Optimize Your Immune System Naturally: Thymic Protein A
The Crucial Role CoQ10 Plays in Fibromyalgia and ME/CFS The Crucial Role CoQ10 Plays in Fibromyalgia and ME/CFS
More Weight Loss than Any Other Discovery in Supplement History More Weight Loss than Any Other Discovery in Supplement History
The Surprising Benefits of Probiotics - What You Didn't Know The Surprising Benefits of Probiotics - What You Didn't Know
Enhance Eyelashes Naturally Enhance Eyelashes Naturally

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map