ProHealth health Vitamin and Natural Supplement Store and Health
Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help

|
|
|
|

Trending News

Missing protein explains link between obesity, diabetes

Fish oil use associated with brain volume preservation

The Brain Boosting and Fatigue Fighting B-12

Genetic basis for distinct type of autism uncovered

Higher vitamin D levels associated with better cancer prognosis

Genetic study suggests causal link between vitamin D deficiency and hypertension

Unsuspected aspect of immune regulation revealed: Role of B cells

IBS, Crohn’s Disease, Colitis, and Other Digestive Disorders

Explaining 'Healthy' Obesity

Sinus Congestion and Sinusitis, Healing Naturally

 
Print Page
Email Article

Chromium Supplementation May Support Improvement in Those with Early Memory Decline

  [ Not Yet Rated ]   [ Discuss This Article ]
By University of Cincinnati • www.ProHealth.com • March 12, 2008


CINCINNATI - Aging adults with early memory decline may benefit from supplementation with chromium picolinate, say University of Cincinnati (UC) researchers. Results of a small pilot study, led by Robert Krikorian, PhD,* a cognitive disorders specialist and UC associate professor of psychiatry [have been presented at recent neurological meetings, including the American Neuropsychiatric Association’s annual meeting, March 1-4, 2008].

Insulin’s Link to Alzheimer’s-Related Changes

Chromium is a nutrient important to insulin signaling and has been shown to improve blood sugar control in patients with diabetes and insulin resistance. Picolinic acid (picolinate) is added to some chromium supplements to aid in absorption. Insulin is a hormone that regulates how sugar (glucose) is stored and moved throughout the body and the brain. When glucose is not properly transported, the risk increases for a number of age-related disorders, including memory loss and dementia.

Insulin resistance - the body’s inability to use insulin efficiently—has been linked to physiological changes associated with Alzheimer’s disease.

Based on his knowledge of insulin’s role in brain function, Krikorian hypothesized that chromium supplementation might improve memory and brain function in older adults suffering from early memory decline. Krikorian and his team conducted a double-blind, placebo-controlled trial of 21 older adults with early memory changes. Eleven study participants received 1,000 micrograms of chromium picolinate supplementation daily for 12 weeks. Ten study participants received a placebo.

Memory, Motor Function Improvements Reflected in Brain Scan Findings

The researchers assessed fine motor control and speed, and evaluated verbal memory by asking participants to learn and remember a list of words. Both assessments were performed prior to treatment and again during week 12. Study results suggest that chromium picolinate supplementation enhanced memory and motor function, says Krikorian.

A subset of participants was also evaluated using functional magnetic resonance imaging (fMRI). The group was asked to perform a memory test during fMRI scans. “Scans of participants receiving chromium picolinate supplementation showed greater activation of the left frontal and left parietal cortices of the brain during the memory test,” says Krikorian. “We did not see the same level of increased activity in the placebo group.

Larger Study Suggested, to Better Quantify Benefit, Preventive Potential

“Our findings suggest that chromium picolinate supplementation in older adults with early memory loss could enhance cognitive function,” says Krikorian. “We would need to further evaluate this treatment option in a larger study to truly assess the benefit and preventive potential.”

Nutrition 21, a New-York based nutritional bioscience company, provided funding and supplements for Krikorian’s study. Co-authors, all from the University of Cincinnati, include Caleb Adler, MD, James Eliassen, PhD, and Marcelle Shidler, PhD.

* * * *

* Robert Krikorian, PhD, krikorr@email.uc.edu
Assoc. Prof. of Clinical Psychiatry
Cognitive Disorders Center, Dept. of Psychiatry
University of Cincinnati, Ohio




Discuss This Article Post a Comment 




[ Be the first to comment on this article ]




 
Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Our FREE
Newsletter
Subscribe Now!
Receive up-to-date ME/CFS & Fibromyalgia treatment and research news
 Privacy Guaranteed  |  View Archives

Featured Products

FibroSleep™ by ProHealth FibroSleep™ by ProHealth
The All-in-One Natural Sleep Aid
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Vitamin D3 Extreme™ by ProHealth Vitamin D3 Extreme™ by ProHealth
50,000 IU Vitamin D3 - Prescription Strength
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function

Natural Remedies

Could a B-12 Deficiency Be Causing Your Symptoms? Could a B-12 Deficiency Be Causing Your Symptoms?
A Breakthrough for Mitochondrial Dysfunction A Breakthrough for Mitochondrial Dysfunction
Protect Against Sun-Induced Skin Aging From The Inside Out Protect Against Sun-Induced Skin Aging From The Inside Out
Itching to Find Dry Skin Relief? Itching to Find Dry Skin Relief?
The Remarkable Benefits of Reishi Medicinal Mushrooms The Remarkable Benefits of Reishi Medicinal Mushrooms

FIBROMYALGIA RESOURCES
What is Fibromyalgia?
Fibromyalgia 101
Fibromyalgia Symptoms
Fibromyalgia Treatments
| CFS RESOURCES
What is CFS?
ME/CFS 101
ME/CFS Symptoms
ME/CFS Treatments
| FORUMS
Fibromyalgia
ME/CFS
ADVANCED MEDICAL LABS
WHOLESALE  |  AFFILIATES
GUARANTEE
CONTACT US
PRIVACY
RSS
SITE MAP
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing