ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Vitamin D supplements, sleep could help manage pain

Bacopa: The Herb That May Increase Your Brain Power

Lilac Oil: More Than Just for Fragrance

Eat More Yogurt and Avoid Osteoporosis

Safflower: An Economically Important Herb That Can Benefit Humans and Animals Alike

What Is Bilberry Good For?

Coffee, herbal tea may help prevent liver fibrosis

Crafty Uses for Carrot Seed Oil

Resveratrol Improves Arteries

New research adds evidence to association between omega 3 levels and brain maintenance

 
Print Page
Email Article

Blood biomarkers for autism spectrum disorder identified

  [ 1 vote ]   [ Discuss This Article ]
www.ProHealth.com • March 20, 2012


“This novel set of biomarkers allows for a reliable blood-based diagnostic tool that may be used in diagnosis and potentially in prognosis of autism spectrum disorder.”

To date there have been no acknowledged biomarkers for autism spectrum disorder. But now three “differentially expressed peptides” that show promise as potential biomarkers have been discovered in the blood plasma of children with autism, according to new research by a team of scientists at Linnaeus and Uppsala Universities in Sweden and the Faculty of Medicine in Tehran, Iran. 

Using advanced mass spectrometric methods to conduct a protein analysis of blood plasma samples from 32 children with ADS (specifically infantile/Kanner syndrome) and 28 neurologically healthy control children, the researchers were able to identify different expressions of three peptides - fragments of an immune system protein known as complement factor C3 -  that discriminated the ASD children from the controls.

According to the spectrometric array, which can depict or map the amounts/mass of different components in a sample, two of the peptides were upregulated and over-represented in the ASD children vs controls, and one peptide was downregulated vs controls. For detail see the full text article (“A novel blood-based biomarker for detection of autism spectrum disorders”) published Mar 13 by Nature Translational Psychiatry.

Though the study sample is small, “the results indicate the potential of our methodological strategy,” says co-author Jonas Bergquist, professor of analytical chemistry and neurochemistry at Uppsala University. “There is already a known connection between this protein and ASD, which further reinforces the findings.”

The Importance of Peptide Analysis

Many diseases are caused by protein alterations inside and outside the body’s cells, the researchers note. By studying protein patterns in tissue and body fluids, these alterations can be mapped to provide important information about underlying causes of disease. And sometimes protein patterns can also serve as biomarkers to enable diagnosis or as a prognosticating tool to monitor the development of a disease.

In this work the researchers were focused on peptides relating to disruptions of the nervous system. The hope is that this new set of biomarkers ultimately will lead to a reliable blood-based diagnostic tool.

Facts About ASD

Autism spectrum disorder is a collective name for neuropsychiatric disturbances that lead to functional impairment in at least two of the three areas that characterize autism:

- Reciprocal social interaction

- Reciprocal verbal and non-verbal communication

- Imagination and behavior.

Autism spectrum disorder encompasses:

- Autism

- Asperger’s syndrome

- Disintegrative disorder (Heller’s syndrome)

- Atypical autism

The study was funded by the Swedish Research Council, among other financiers.

Source: Based on Uppsala University press release, Mar 23, 2012; research report “A novel blood-based biomarker for detection of autism spectrum disorders,” Nature Translational Psychiatry, Mar 13, 2012, M Momeni, et al.




Post a Comment

Featured Products From the ProHealth Store
Energy NADH™ 12.5mg FibroSleep™ Mitochondria Ignite™ with NT Factor®

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
NAD+ Ignite with Niagen

Featured Products

Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%

Natural Remedies

Irritable Bowel Syndrome: Unlocking the Secrets of Peppermint, Acacia and Fennel Irritable Bowel Syndrome: Unlocking the Secrets of Peppermint, Acacia and Fennel
Ubiquinol - A More Advanced Form of the Energy Producing Nutrient CoQ-10 Ubiquinol - A More Advanced Form of the Energy Producing Nutrient CoQ-10
The New Dual Activation Pain Relief Cream The New Dual Activation Pain Relief Cream
Breaking Through the Mental Fog Breaking Through the Mental Fog
Itching to Find Dry Skin Relief? Itching to Find Dry Skin Relief?

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map