ProHealth health Vitamin and Natural Supplement Store and Health
Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help

|
|
|
|

Trending News

CDC Whistleblower Reveals Widespread Manipulation of Scientific Data and Top-Down Pressure on CDC Sc...

Irritable Bowel Syndrome: Unlocking the Secrets of Peppermint, Acacia and Fennel

How Glutathione Can Save Your Life

9 Health Benefits of Cucumbers

Coenzyme Q10 Benefits Symptoms in Gulf War Veterans: Results of a Randomized Double-Blind Study

Brain inflammation dramatically disrupts memory retrieval networks, UCI study finds

VIDEO: Relaxation - Ocean Voyager Part I

Clinical trial demonstrates safety, effectiveness of immunotherapy for AdV, BKV, and herpesviruses i...

Scientists discover how to 'switch off' autoimmune diseases

New estrogen-based compound suppresses binge-like eating behavior in female mice

 
Print Page
Email Article

Trial of 5-Minute Subcutaneous Rituximab Injection: Positive Results

  [ 7 votes ]   [ Discuss This Article ]
www.ProHealth.com • December 10, 2012


Dec 8: Basil, Switzerland-based Roche pharmaceuticals company reports positive results from two international phase III trials of its MabThera – a form of rituximab that can be injected under the skin rather than delivered intravenously.

Rituximab is used to treat illnesses involving overactive or dysfunctional immune B cells, such as lymphomas, and some autoimmune disorders such as RA; and, according to pilot trials may benefit at least a subset of ME/CFS patients. (For background click here.)

The MabThera studies suggest this subcutaneously delivered rituximab, submitted for approval to the European Medicines Agency on Dec 4:

• Requires much less patient time in an infusion center (5 minutes vs. 2-1/2 hours for administration)

• Delivers comparable (“noninferior”) concentrations in the blood vs the IV mode of administration, with similar, mostly mild to moderate adverse event and administration related reactions.

• Based on an exploratory switch from IV to subcutaneous administration, does not appear to compromise proven response rates (in this case anti-lymphoma efficacy).

• And as a ready-to-use formulation should reduce pharmacy and staff preparation and administration time.

Source: Based on Roche press release, Dec 8, 2012. For full details, go to http://www.roche.com/med-cor-2012-12-08b.htm




Please Discuss This Article:   Post a Comment 



[ Be the first to comment on this article ]




 
Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Our FREE
Newsletter
Subscribe Now!
Receive up-to-date ME/CFS & Fibromyalgia treatment and research news
 Privacy Guaranteed  |  View Archives

Save on Vitamins and Supplements

Featured Products

Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Vitamin D3 Extreme™ by ProHealth Vitamin D3 Extreme™ by ProHealth
50,000 IU Vitamin D3 - Prescription Strength
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
FibroSleep™ by ProHealth FibroSleep™ by ProHealth
The All-in-One Natural Sleep Aid

Natural Remedies

The Remarkable Benefits of Reishi Medicinal Mushrooms The Remarkable Benefits of Reishi Medicinal Mushrooms
The Big Blue Fish that Helps Chase the Blues Away The Big Blue Fish that Helps Chase the Blues Away
Front Line Defense Against Colds & Flu - Support for Healthy Immune System Balance Front Line Defense Against Colds & Flu - Support for Healthy Immune System Balance
The Revolutionary 'Good Fat' That Promotes Heart, Brain, Bone and Joint Health The Revolutionary 'Good Fat' That Promotes Heart, Brain, Bone and Joint Health
Magnesium + Malic Acid: One-Two Punch for Pain & Fatigue Magnesium + Malic Acid: One-Two Punch for Pain & Fatigue

FIBROMYALGIA RESOURCES
What is Fibromyalgia?
Fibromyalgia 101
Fibromyalgia Symptoms
Fibromyalgia Treatments
| CFS RESOURCES
What is CFS?
ME/CFS 101
ME/CFS Symptoms
ME/CFS Treatments
| FORUMS
Fibromyalgia
ME/CFS
ADVANCED MEDICAL LABS
WHOLESALE  |  AFFILIATES
GUARANTEE
CONTACT US
PRIVACY
RSS
SITE MAP
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing