ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

10 Fibro-Friendly Foods with a Bonus: Beautiful Skin

Fight Back! Win the War Being Waged Against Your Immune System

Studies Show that Magnesium L-threonate Improves Brain Plasticity, Leading to Direct and Significant...

The role of microbiota and intestinal permeability in the pathophysiology of autoimmune and neuroimm...

Clary Sage Oil May Be Pricey, but Its Benefits Are Priceless

Component of red wine, grapes can help to reduce inflammation, study finds

Poly MVA: A Novel Therapy for Increasing Energy, Repairing DNA, and Promoting Overall Health

Pumpkin Pie Turmeric Breakfast Smoothie - Vegan + Gluten-Free

Omega-3 fatty acid stops known trigger of lupus

What’s Fenugreek Good For?

Print Page
Email Article

Anti-inflammatory Compound Helps Woman With CFS Return to Work

  [ 3 votes ]   [ 2 Comments ] • March 16, 2013

Editor's Note:  Alpha-1 antitrypsin (AAT) protects tissues from enzymes of inflammatory cells, especially neutrophil elastase. It is excreted by neutrophils and macrophages during inflammation, and destroys both bacteria and host tissue.

Alpha-1 antitrypsin and chronic fatigue syndrome: a case study from pathophysiology to clinical practice

~Source: Pain Management, March 2013

By José Alegre at el.


Background: Several lines of evidence support the involvement of inflammatory and immunologic abnormalities in chronic fatigue syndrome (CFS). Since recent studies have shown that alpha-1 antitrypsin (AAT) possesses anti-inflammatory properties, the potential therapeutic effect of AAT treatment on CFS has been investigated. 

Case presentation: A 49-year-old woman diagnosed with CFS was treated with intravenous infusions of a human plasma-derived AAT concentrate (60 mg/kg body weight weekly for 8 consecutive weeks). The patient’s monocyte elastase, a regulator of inflammatory processes, was 1170 U/mg. At completion of treatment, improvement in maximal workload was observed (54.0–71.7% of predicted). Additionally, amelioration in working memory (scores: 83–94) and perceptual organization (scores: 75–83) were detected on the Wechsler Adult Intelligence Scale-III test. Monocyte elastase decreased to a normal range (<150 U/mg). Improvement in functional capacity allowed the patient to work in part-time employment. 

Conclusion: These findings suggest a possible role for AAT in the treatment of CFS.

Source: Pain Management, March 2013, Vol. 3, No. 2, Pages 119-122 , DOI 10.2217/pmt.12.84. José Alegre, Chronic Fatigue Syndrome Unit, Hospital Vall d'Hebron, Passeig Vall Hebron 119-129, 08035 Barcelona, Spain; Sandra Camprubí, Clinical Trials & Pharmacovigilance Department, Instituto Grifols S.A. Can Guasch 2, 08150 Parets del Vallès, Barcelona, Spain; and Ana García-Quintana, Chronic Fatigue Syndrome Unit, Centro Médico Delfos, Avinguda de Vallcarca 151, 08023 Barcelona, Spain.

Post a Comment

Featured Products From the ProHealth Store
FibroSleep™ Ultra ATP+, Double Strength Optimized Curcumin Longvida®

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products

Article Comments Post a Comment

One woman
Posted by: roge
Mar 16, 2013
is this some kind of joke - one woman - cmon

Dont even bother telling me if something works unless you have at least 100 patients and double blinded - please
Reply Reply

Posted by: roge
Mar 16, 2013
ok i may have been a bit harsh above as at least conclusion says may play a possible role - but still


Natural Pain Relief Supplements

Featured Products

Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%

Natural Remedies

Mitochondria-Booster NIAGEN® Shows Promise in First Human Clinical Trial Mitochondria-Booster NIAGEN® Shows Promise in First Human Clinical Trial
The Remarkable Benefits of Reishi Medicinal Mushrooms The Remarkable Benefits of Reishi Medicinal Mushrooms
Thyroid Health and Fibromyalgia Thyroid Health and Fibromyalgia
"It's Not Easy Being Green" - But It Is Healthy
Are You Obtaining the Proper Enzymes? Are You Obtaining the Proper Enzymes?

ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
Credit Card Processing
Be the first to know about new products, special discounts and the latest health news. *New subscribers only

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2016 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map