ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help

|
|
|
|

Trending News

Strengthening DNA to Prevent Inflammation, Heart Disease, Dementia and More

Optimal Prostate Defense Requires a Multi-Modal Strategy

The Most Powerful Natural Antioxidant Discovered to Date - Hydroxytyrosol

How Lipoic Acid Preserves Critical Mitochondrial Function

Omega-3 Fatty Acids Increase Brain Volume

Magnesium: The Missing Key to Your Health?

New Option For Chronic Fatigue Syndrome

Living Longer, Healthier Lives with Resveratrol

Iodine: The Forgotten Medicine

What You Need to Know About Folate and B12

 
Print Page
Email Article

Small Intestinal Bacterial Overgrowth in Patients with Interstitial Cystitis and Gastrointestinal Symptoms - Source: Digestive Disases and Sciences, Oct 12, 2007

  [ 127 votes ]   [ Discuss This Article ]
By LB Weinstock, et al. • www.ProHealth.com • October 18, 2007


[Note: the lactulose breath test measures the levels of hydrogen and methane in the breath – two gases produced by fermented bacteria. Nonabsorbable antibiotics are taken orally and do not pass the gastrointestinal wall into the blood stream. Prokinetic agents are used to speed movement of food through the GI tract.]

Purpose: Interstitial cystitis (IC) often coexists with irritable bowel syndrome (IBS). IBS may be explained by small-intestinal bacterial overgrowth (SIBO), which increases immune activation and visceral hypersensitivity.

This prospective pilot study tested hypotheses that IC patients with gastrointestinal (GI) symptoms have SIBO, that nonabsorbable antibiotic use improves symptoms, and that improvement is sustained by prokinetic therapy.

Methods: Consecutive IC patients with GI symptoms had lactulose breath testing (LBT). Those with abnormal results received rifaximin 1,200-1,800 mg/day for 10 days then tegaserod 3 mg/nightly. Questionnaires addressed IC and GI global improvement.

Results: Of 21 patients, 17 (81%) had abnormal LBTs. Of 15 patients treated, GI global improvement was moderate to great in 11 (73%) and sustained in ten (67%). IC global improvement was moderate to great in six (40%) and sustained in seven (47%).

Conclusions: A majority of IC patients and GI symptoms had an abnormal lactulose breath test suggesting small intestinal bacterial overgrowth. Rifaximin improved symptoms, which was sustained by tegaserod.

Source: Digestive Diseases and Sciences. 2007 Oct 12; [Epub ahead of print] PMID: 17932763, by Weinstock LB, Klutke CG, Lin HC. Washington University School of Medicine, St. Louis, MO, USA.




Please Discuss This Article:   Post a Comment 



[ Be the first to comment on this article ]




 
Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Our FREE
Newsletter
Subscribe Now!
Receive up-to-date ME/CFS & Fibromyalgia treatment and research news
 Privacy Guaranteed  |  View Archives

Save on Immune Support Supplements

Featured Products

Optimized Curcumin Longvida® by ProHealth Optimized Curcumin Longvida® by ProHealth
Supports Cognition, Memory & Overall Health
Vitamin D3 Extreme™ by ProHealth Vitamin D3 Extreme™ by ProHealth
50,000 IU Vitamin D3 - Prescription Strength
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
FibroSleep™ by ProHealth FibroSleep™ by ProHealth
The All-in-One Natural Sleep Aid

Natural Remedies

Three-Step Strategy to Reverse Mitochondrial Aging Three-Step Strategy to Reverse Mitochondrial Aging
Research Links Green Tea to Weight Loss Research Links Green Tea to Weight Loss
Are You Obtaining the Proper Enzymes? Are You Obtaining the Proper Enzymes?
Itching to Find Dry Skin Relief? Itching to Find Dry Skin Relief?
Live Longer: Groundbreaking Research on Omega-3s Live Longer: Groundbreaking Research on Omega-3s

FIBROMYALGIA RESOURCES
What is Fibromyalgia?
Fibromyalgia 101
Fibromyalgia Symptoms
Fibromyalgia Treatments
| CFS RESOURCES
What is CFS?
ME/CFS 101
ME/CFS Symptoms
ME/CFS Treatments
| FORUMS
Fibromyalgia
ME/CFS
ADVANCED MEDICAL LABS
WHOLESALE  |  AFFILIATES
GUARANTEE
CONTACT US
PRIVACY
RSS
SITE MAP
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing