ProHealth health Vitamin and Natural Supplement Store and Health
Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help

|
|
|
|

Trending News

Missing protein explains link between obesity, diabetes

The Brain Boosting and Fatigue Fighting B-12

Genetic basis for distinct type of autism uncovered

Unsuspected aspect of immune regulation revealed: Role of B cells

IBS, Crohn’s Disease, Colitis, and Other Digestive Disorders

Sinus Congestion and Sinusitis, Healing Naturally

Explaining 'Healthy' Obesity

New Science Destroys the Saturated Fat Myth

Ginger's Many Evidence-Based Health Benefits Revealed

Omega 3 Fatty Acids Lessen Severity of Osteoarthritis in Mice

 
Print Page
Email Article

Supplements of 20 micrograms/day cholecalciferol [vitamin D3] optimized serum 25-Hydroxyvitamin D concentrations in 80% of premenopausal women in winter - Source: Journal of Nutrition, March 2009

  [ 6 votes ]   [ Discuss This Article ]
By Monica L Nelson, Susan S Sullivan, et al. • www.ProHealth.com • March 9, 2009


[Note: ug stands for microgram, or one thousanth of a miligram. Most supplements express dosages in international units (iu) – which is an international standard of an agreed upon biological effect. This varies by the substance measured. For vitamin D3, the conversion to iu is ug times 40; so 22 ug/day – the amount given to these young women starting in September - translates to 880 iu/day. Blood testing for 25(OH)D is considered the best indicator of vitamin D status.]

The serum 25-hydroxyvitamin D [25(OH)D] response to daily supplementation with 20 ug cholecalciferol (D3) during winter in predominantly white premenopausal women living in Maine was measured and the effects of body composition and hormonal contraceptive use on baseline serum 25(OH)D concentrations and the response to supplementation were examined.

A total of 112 women (22.2 ± 3.7 years old) received placebo from March 2005 until September 2005 when they were randomized to receive either placebo or 20 ug/d D3 through February 2006. Eighty-six women completed the study.

Actual mean D3 content of the supplements was 22 ug per capsule. In February 2005 the serum 25(OH)D concentration was 62.0 ± 23.4 nmol/L (mean ± SD).

Serum 25(OH)D concentrations increased by 35.3 ± 23.2 nmol/L from February 2005 to February 2006 in the treatment group, significantly more than the 10.9 ± 16.9 nmol/L increase in the placebo group. Treatment group, magnitude of summer increase in 25(OH)D, estrogen dose, and baseline serum 25(OH)D concentrations, but not body fat, were significant predictors of the 1-year change in 25(OH)D concentrations used to assess the magnitude of the response to supplementation.

Daily supplementation with 20 ug D3 during winter achieved optimal 25(OH)D concentrations (75 nmol/L or more) in 80% of participants, indicating that this dose is adequate to optimize vitamin D status in most young women in Maine.

Source: Journal of Nutrition, March 2009;139(3). Nelson ML, Blum JM, Hollis BW, Rosen C, Sullivan SS. University of Maine, Department of Food Science and Human Nutrition, Orono, Maine; Dietary Supplement Research Group, Saco, Maine; Medical University of South Carolina, Department of Pediatrics, Charleston, South Carolina; Maine Medical Center Research Institute, Scarborough, Maine, USA. [E-mail: susans@maine.edu]





Discuss This Article Post a Comment 




[ Be the first to comment on this article ]




 
Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Our FREE
Newsletter
Subscribe Now!
Receive up-to-date ME/CFS & Fibromyalgia treatment and research news
 Privacy Guaranteed  |  View Archives

Save on Your Next Order

Featured Products

Optimized Curcumin Longvida® by ProHealth Optimized Curcumin Longvida® by ProHealth
Supports Cognition, Memory & Overall Health
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Vitamin D3 Extreme™ by ProHealth Vitamin D3 Extreme™ by ProHealth
50,000 IU Vitamin D3 - Prescription Strength
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%

Natural Remedies

Protect Against Sun-Induced Skin Aging From The Inside Out Protect Against Sun-Induced Skin Aging From The Inside Out
Repair Damaged Mitochondria and Reduce Fatigue Up to 45% Repair Damaged Mitochondria and Reduce Fatigue Up to 45%
Red: The Color of Energy, Health, and B-12 Red: The Color of Energy, Health, and B-12
The Brain Boosting and Fatigue Fighting B-12 The Brain Boosting and Fatigue Fighting B-12
Front Line Defense Against Colds & Flu - Support for Healthy Immune System Balance Front Line Defense Against Colds & Flu - Support for Healthy Immune System Balance

FIBROMYALGIA RESOURCES
What is Fibromyalgia?
Fibromyalgia 101
Fibromyalgia Symptoms
Fibromyalgia Treatments
| CFS RESOURCES
What is CFS?
ME/CFS 101
ME/CFS Symptoms
ME/CFS Treatments
| FORUMS
Fibromyalgia
ME/CFS
ADVANCED MEDICAL LABS
WHOLESALE  |  AFFILIATES
GUARANTEE
CONTACT US
PRIVACY
RSS
SITE MAP
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing