ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help

|
|
|
|

Trending News

Vitamin D Deficiency Linked to Neurological Diseases; Also Raises Risk of Asthma Attacks, and More

7 Best Foods You Can Eat

Study: Doubling saturated fat in the diet does not increase saturated fat in blood

The Gut Microbiome and the Brain

Fight Inflammation and Promote Cognitive Health with High-OPC Grape Seed

CoQ10 supplementation reduces statin-related muscle pain in randomized trial

Controlling obesity with potato extract

Plant used in traditional Chinese medicine may treat metabolic diseases and obesity

Natural Gut Viruses Join Bacterial “Cousins” in Maintaining Health and Fighting Infections

Proton pump inhibitors decrease diversity in gut microbiome, increase risk for complications

 
Print Page
Email Article

Association between serum ferritin [stored iron] level and fibromyalgia syndrome – Source: European Journal of Clinical Nutrition, Jan 20, 2010

  [ 53 votes ]   [ 7 Comments ]
By O Ortancil, et al. • www.ProHealth.com • January 24, 2010


[Note: Ferritin is an iron-storage protein in cells. It binds to iron, keeps it in a dissolvable state, and makes it non-toxic to the cells around it.]

Background/Objectives:

• Iron is essential for a number of enzymes involved in neurotransmitter synthesis.

• Analysis of cerebrospinal fluid in fibromyalgia syndrome (FMS) has shown a reduction in the concentration of biogenic amine metabolites, including dopamine, norepinephrine and serotonin.

• This study aimed to investigate the association of ferritin with FMS.

Subjects/Methods: A total of 46 patients with primary FMS participated in this case-control study, and 46 healthy females who were age matched to the patients were used as the control group. Venous blood samples collected from all subjects were used to evaluate serum ferritin, vitamin B12 and folic acid levels.

Results: The mean serum ferritin levels in the fibromyalgia (FM) and control groups were 27.3+/-20.9 and 43.8+/-30.8 ng/ml, respectively, and the difference was statistically significant (P=0.003). Binary multiple logistic regression analysis with age, body mass index, smoking status and vitamin B12, as well as folic acid and ferritin levels showed that having a serum ferritin level of less than 50 ng/ml caused a 6.5-fold increased risk for FMS.

Conclusions: Our study implicates a possible association between FM and decreased ferritin level, even for ferritin in normal ranges.

We suggest that iron as a cofactor in serotonin and dopamine production may have a role in the etiology of FMS.

Source: European Journal of Clinical Nutrition, Jan 20, 2010;26(2):168-72. PMID: 20087382, by Ortancil O, Sanli A, Eryuksel R, Basaran A, Ankarali H. Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Zonguldak Karaelmas University, Zonguldak,Turkey. [E-mail: ozgurortancil@yahoo.com]




Please Discuss This Article:   Post a Comment 

Maybe ...
Posted by: fnx3
Jan 27, 2010
Well - my iron & ferritin levels were found to be deficient about 18 months ago - that was 6 months after my Fibro diagnosis - then 10 months later it was discovered that I had a pre-cancerous (bleeding) polyp in my colon & it was removed PLUS the GE recommended that I adopt a Gluten Free diet until he performed a gastroscopy at my next colonoscopy to determine if I was Celiac. BINGO! A few months later my massive brain fog & physical fatigue has gone & not returned (after 2 years of being fully home-bound!). Sooooo ... I highly recommend ANYONE with a diagnosis of Fibromyalgia also request tests for Celiac disease.
Reply Reply

Question for previous poster fnx
Posted by: CuddleBear
Jan 27, 2010
How do they test for Celiac disease? I too, have iron deficiency (diagnosed last year) and have had FM for about six years. We live way out in the mountains and I don't know if my country doctor would even know what Celiac Disease is! What are the symptoms? What is the treatment?
Reply Reply

 
Coeliac Disease/Fibromyalgia
Posted by: Tias_33
Jan 27, 2010
Hi I have had Fibromyalgia since I was 11 yewars old but of cause was not diagnosed until well into my 30's.

I also have Coelic Disease. For the member who asked how you are diagnosed? what are the symptoms?

My symptoms were not being able to keep anything I eat in my bowel had constant diaroah sorry spelling, you can have it the other way constipation your very thin and there are other symptoms there not nice until you are diagnosed. Nothing stays in your gullett it goes straight through you.

The way you are diagnosed at first they may test your bloods. The only true way is a Endoscopy down the Gulett a biobsy and that way they can get a true diagnosis. It is the upper bowel which is inflammed and the lower one to.

Coeliac Disease you can not at all have anything with Wheat you must eat a Gluten free Die. Once your on the proper diet you will see a Huge Improvement within 2 weeks. it can be a bind finding what you can and what you can not have to eat.

I belong to the Coeliac Society and am a member get the Food Dietry book every year as well as up to day magazines.

I have never heard of anyone who has Coeliac Disease and Fibromyalgia is cured. I know many Fibros go onto the gluten free diet and say it helps there fibro. For me it does nothing.

I am pleased for you that it has helped you. I hope for the member who wanted info on Coeliac Disease has helped you Love Tia

 


FERRITIN LEVELS
Posted by: helens939
Jan 27, 2010
My nutritionist feels that my ferritin levels are on the high side and has suggested iron, total iron binding capacity and iron levels should be investigated. Apparently this could indicate, oxidative stress, low grade inflammation or parasites. So it leads me to wonder where we are with this piece of information, both indicating different things.
Reply Reply

Celiac diagnosis
Posted by: fnx3
Jan 27, 2010
Hi, Well the way it happened for me was first by just observing the improvement in my health whenever I cut gluten products out of my diet - then the Gastroenterologist observing the same thing in combination with the anaemia, osteoporosis & Rheumatoid Arthritis. Some people with Celiac may also experience obvious digestive problems like diarrhea or constipation, bloating, colic & wind but not always - so it can be overlooked as an obvious gut condition. There are blood tests that can show if there is a hightened immune response in the gut but the big decider is the actual Gastroscopy which takes a tiny bit of the gut lining & observes it in the laboratory - they can then clearly see if the little "villi" are flat or not - they should be standing up nice & separately but in Celiac disease they are worn out, wrecked & lying down flat - thus not able to absorb the nutrients from the food as it passes through - hence all the deficiencies.
Reply Reply

 
To Tias 33 ..
Posted by: fnx3
Jan 27, 2010
Nice reply! (How did you manage to add it as a "sub comment"??? - I couldn't work that out)

Yes - this is what I am now watching for - to see just how far my health will improve with the gluten free diet - I wonder if it will eliminate my Fibro symptoms altogether - I am hopeful but it has only been 3 months. And then of course I also have only recently started to experience RA attacks in my joints so that adds more negative symptoms esp. fatigue during a attack. Oh Brother! where does it end - but I am also hopeful that by reducing the immune system response as per Celiac that it may also reduce the RA attacks too, somehow ... like I say "hopeful".

 


Celiac decease is . . .
Posted by: vickip5200
Jan 27, 2010
Celiac decease is determined with a blood test, I've been told. I will be going to my doctor for the test for it. I have been gluten free for a week and already lost weight (I'm on a low fat and calorie diet as well) and the night sweats have lessened dramticly. I've had FM for nearly 20 years and need all the help I can get.
Reply Reply


Post a Comment

 
Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Our FREE
Newsletter
Subscribe Now!
Receive up-to-date ME/CFS & Fibromyalgia treatment and research news
 Privacy Guaranteed  |  View Archives

Save on Nutritional Supplement Orders

Featured Products

Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Optimized Curcumin Longvida® by ProHealth Optimized Curcumin Longvida® by ProHealth
Supports Cognition, Memory & Overall Health
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium

Natural Remedies

Front Line Defense Against Colds & Flu - Support for Healthy Immune System Balance Front Line Defense Against Colds & Flu - Support for Healthy Immune System Balance
Dreaming of a Good Night's Sleep? Dreaming of a Good Night's Sleep?
Are You Obtaining the Proper Enzymes? Are You Obtaining the Proper Enzymes?
Running on Empty? Fuel Up with NADH Running on Empty? Fuel Up with NADH
The Curcumin Revolution: The Curcumin Revolution: "Golden" Ticket to Better Health

FIBROMYALGIA RESOURCES
What is Fibromyalgia?
Fibromyalgia Diagnosis
Fibromyalgia Symptoms
Fibromyalgia Treatments
| CFS RESOURCES
What is CFS?
ME/CFS Diagnosis
ME/CFS Symptoms
ME/CFS Treatments
| FORUMS
Fibromyalgia
ME/CFS
ADVANCED MEDICAL LABS
WHOLESALE  |  AFFILIATES
GUARANTEE  |  PRIVACY
CONTACT US
LIBRARY
RSS
SITE MAP
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing