ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help

Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Delayed diagnosis of Lyme disease has devastating effect on patients

Missing Link Found Between Brain, Immune System - Major Disease Implications

National Institutes Of Health Discovers Protective Effects Of Coffee

The dormant blood microbiome in chronic, inflammatory diseases

Fatigue & Fibro Fog: Could You Have a B-12 Deficiency?

Association of lyme disease and schizoaffective disorder, bipolar type: Is it inflammation mediated?

Adapt to Stress Naturally with These Power Herbs

Curcumin Made 65X More Bioavailable - Modern Take on a "Golden" Spice Busts Brain Fog, Joint & Body ...

Researchers’ discovery may explain difficulty in treating Lyme disease

Discovering Coffee's Unique Health Benefits

 
Print Page
Email Article

Cytokines across the night in chronic fatigue syndrome with and without Fibromyalgia - Source: Clinical and Vaccine Immunology, Feb 24, 2010

  [ 11 votes ]   [ Discuss This Article ]
By Toru Nakamura, Benjamin H. Natelson, et al. • www.ProHealth.com • March 11, 2010


The symptoms of chronic fatigue syndrome are consistent with cytokine dysregulation. [Cytokines are cell-to-cell 'signaling molecules' secreted by immune cells.] This has led to the hypothesis of immune dysregulation as the cause of this illness.

To further test this hypothesis, we did repeated blood sampling for cytokines while patients and matched healthy controls slept in the sleep lab.

Because no one method for assaying cytokines is acknowledged to be better than another, we assayed for protein in serum, message in peripheral blood lymphocytes (PBLs) and function in resting and stimulated PBLs

• We found no evidence of pro-inflammatory cytokine upregulation.

• Instead, in line with some of our earlier studies, we did find some evidence to support a role for an increase in IL-10 (Interleukin-10), an anti-inflammatory cytokine.

Although the changes were small, they may contribute to the common complaint of CFS patients of disrupted sleep.

Source: Clinical and Vaccine Immunology, Feb 24, 2010;03-11. PMID: 20181767 Nakamura T, Schwander SK, Donnelly R, Ortega F, Togo F, Broderick G, Yamamoto Y, Cherniack NS, Rapoport D, Natelson BH. Pain & Fatigue Study Center, and Departments of Neurosciences and Medicine, UMDNJ-New Jersey Medical School, Newark NJ; Department of Work Stress Control, Japan National Institute of Occupational Safety and Health, Kawasaki, Japan; Department of Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Canada; Educational Physiology Laboratory, Graduate School of Education, The University of Tokyo; Department of Medicine, Division of Pulmonary and Critical Care Medicine, NYU School of Medicine, New York, New York, USA. [Email: natelsbe@umdnj.edu]




Please Discuss This Article:   Post a Comment 



[ Be the first to comment on this article ]




 
Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Our FREE
Newsletter
Subscribe Now!
Receive up-to-date ME/CFS & Fibromyalgia treatment and research news
 Privacy Guaranteed  |  View Archives

Save on Vitamins and Supplements

Featured Products

Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength

Natural Remedies

Olea25 Olive Hydroxytyrosol Hits Astonishing 68,000+ ORAC Antioxidant Value Olea25 Olive Hydroxytyrosol Hits Astonishing 68,000+ ORAC Antioxidant Value
IBS, Crohn’s Disease, Colitis, and Other Digestive Disorders IBS, Crohn’s Disease, Colitis, and Other Digestive Disorders
Stop Bacteria With Nature's Antibiotics Stop Bacteria With Nature's Antibiotics
Anti-Inflammatory Properties of Tart Cherry Anti-Inflammatory Properties of Tart Cherry
Undenatured Type II Collagen - Chicken Soup for Your Joints Undenatured Type II Collagen - Chicken Soup for Your Joints

FIBROMYALGIA RESOURCES
What is Fibromyalgia?
Fibromyalgia Diagnosis
Fibromyalgia Symptoms
Fibromyalgia Treatments
| CFS RESOURCES
What is CFS?
ME/CFS Diagnosis
ME/CFS Symptoms
ME/CFS Treatments
| FORUMS
Fibromyalgia
ME/CFS
ADVANCED MEDICAL LABS
WHOLESALE  |  AFFILIATES
GUARANTEE  |  PRIVACY
CONTACT US
LIBRARY
RSS
SITE MAP
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing