ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help

|
|
|
|

Trending News

Guarding Against the Dangers of Vitamin D Deficiency

Omega-3 fatty acids, vitamin D may control brain serotonin, affecting behavior and psychiatric disor...

How Glutathione Can Save Your Life

New Dietary Guidelines Reverse Flawed Recommendations on Cholesterol

Long term antibiotic therapy may be an effective treatment for children co-morbid with Lyme disease ...

Beyond Depression... SAMe Broad-Spectrum Protection Against Disorders Of Aging

Anticancer Properties Of Saffron

BPA exposure linked to autism spectrum disorder, study reports

Omega-3 Fatty Acids Appear to Protect Damaged Heart After Heart Attack

Nine superfruits and super seeds to add to your diet

 
Print Page
Email Article

[Pregabalin for fibromyalgia - can we rely on the pharmaceutical industry?] [Article in Norwegian] – Source: Tidsskr Nor Laegeforen, May 20, 2010

  [ 61 votes ]   [ Discuss This Article ]
By R Holtedahl • www.ProHealth.com • May 24, 2010


Background: Use of Pregabalin [Lyrica®] has increased considerably in Norway during the last years. One explanation is prescription to patients with diffuse musculoskeletal pain. The aim of the article is to clarify the effect of pregabalin in fibromyalgia.

Material and methods:
This article is based on literature identified through searches in Medline and public trial registries.

Results: Six randomized, double-blind clinical trials were identified (three of them in peer-reviewed journals) and Pfizer had initiated and sponsored them all.

• The three trials published in peer-reviewed journals used a numerical rating scale for pain as the primary endpoint, and all trials reported statistically significant improvements on mean pain scores in relation to placebo. The mean pain reduction was between 9% and 15%.

• Effects on secondary endpoints varied considerably, both within and between the studies.

• Negative results were seldom mentioned in the abstracts, and secondary endpoints were reported incompletely.

All 19 reviews referred to one or more of the clinical trials, and were generally limited to describing main results.

Interpretation: Recommendations for pregabalin in treatment of patients with fibromyalgia are based on rather weak evidence. Until trials independent of industry-funding are published, the role of pregabalin in treatment of fibromyalgia remains unclear.

Source: Tidsskr Nor Laegeforen, May 20, 2010;130(10):1032-1036. PMID: 20489805, by Holtedahl R. Avdeling for Fysikalsk Medisin og Rehabilitering Sykehuset Buskerud [Email: robi-hol@online.no]




Please Discuss This Article:   Post a Comment 



[ Be the first to comment on this article ]




 
Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Our FREE
Newsletter
Subscribe Now!
Receive up-to-date ME/CFS & Fibromyalgia treatment and research news
 Privacy Guaranteed  |  View Archives

Save on Vitamins and Supplements

Featured Products

Optimized Curcumin Longvida® by ProHealth Optimized Curcumin Longvida® by ProHealth
Supports Cognition, Memory & Overall Health
Vitamin D3 Extreme™ by ProHealth Vitamin D3 Extreme™ by ProHealth
50,000 IU Vitamin D3 - Prescription Strength
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
FibroSleep™ by ProHealth FibroSleep™ by ProHealth
The All-in-One Natural Sleep Aid

Natural Remedies

Green Coffee Extract: Unique Obesity Intervention Green Coffee Extract: Unique Obesity Intervention
Everything You Always Wanted to Know About Sleep But Were Too Tired to Ask Everything You Always Wanted to Know About Sleep But Were Too Tired to Ask
Energy Breakthrough - One Fibromyalgia Patient’s Fortuitous Discovery Energy Breakthrough - One Fibromyalgia Patient’s Fortuitous Discovery
Magnesium + Malic Acid: One-Two Punch for Pain & Fatigue Magnesium + Malic Acid: One-Two Punch for Pain & Fatigue
Reversing Neurodegeneration with a New Magnesium Compound Reversing Neurodegeneration with a New Magnesium Compound

FIBROMYALGIA RESOURCES
What is Fibromyalgia?
Fibromyalgia Diagnosis
Fibromyalgia Symptoms
Fibromyalgia Treatments
| CFS RESOURCES
What is CFS?
ME/CFS Diagnosis
ME/CFS Symptoms
ME/CFS Treatments
| FORUMS
Fibromyalgia
ME/CFS
ADVANCED MEDICAL LABS
WHOLESALE  |  AFFILIATES
GUARANTEE  |  PRIVACY
CONTACT US
LIBRARY
RSS
SITE MAP
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing