Activate Now
 
ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

The New Dual Activation Pain Relief Cream

SURVEY RESULTS: Medical Marijuana

High serum omega-6 polyunsaturated fatty acid concentrations linked to lower risk of type 2 diabetes

Recipe: Mega-Golden Milk

Vitamin D supplementation shows promise for Hashimoto's thyroiditis

A Paleolithic-type diet may help reduce future risk of diabetes and cardiovascular disease

Large whey protein breakfast may help manage type 2 diabetes

Decreased levels of vitamin D associated with reduced methylation in African American teens

Selenium — What Is it and Where Do I Get It?

Meta-analysis adds evidence to antidepressant effect for omega-3

 
Print Page
Email Article

Acupuncture Gains 'New Scientific Heft' - Releases Natural Pain Killer Adenosine

  [ 57 votes ]   [ 2 Comments ]
www.ProHealth.com • May 31, 2010


Acupuncture Gains 'New Scientific Heft' - Releases Natural Pain Killer Adenosine

For those still harboring doubts about acupuncture, this discovery adds proof of local chemical release in the peripheral nervous system to the recent discovery of a central nervous system endorphin response.

Scientists have taken another important step toward understanding just how sticking needles into the body can ease pain.

In a paper published online May 30 in Nature Neuroscience (“Adenosine A1 receptors mediate local antinociceptive effects of acupuncture”), researchers at the University of Rochester’s Center for Translational Neuromedicine have identified the molecule adenosine as a central player in parlaying some of the effects of acupuncture in the body.

Building on that knowledge, the scientists were able to triple the beneficial effects of acupuncture in mice by adding a medication approved by the FDA to treat leukemia in people.

The research focuses on adenosine, a natural compound known for its role in regulating sleep, for its effects on the heart, and for its anti-inflammatory properties. But adenosine also acts as a natural painkiller, becoming active in the skin after an injury to inhibit nerve signals and ease pain in a way similar to lidocaine. [According to the paper, mechanical or electrical tissue stimulation releases ATP (adenosine triphosphate) from the cells - and ATP, the stuff of cellular energy, quickly degrades to adenosine.]

In the current study, scientists found that the chemical is also very active in deeper tissues affected by acupuncture. The Rochester researchers looked at the effects of acupuncture on the peripheral nervous system – the nerves in our body that aren’t part of the brain and spinal cord.

Acupuncture’s Multiple Anti-Pain Effects

The research complements a rich, established body of work showing that in the central nervous system, acupuncture also creates signals that cause the brain to churn out natural pain-killing endorphins.(1)

The new findings add to the scientific heft underlying acupuncture, said neuroscientist Maiken Nedergaard, MD, DMSc, who led the research. Her team presents the work this week at a scientific meeting, Purines 2010, in Barcelona, Spain.

“Acupuncture has been a mainstay of medical treatment in certain parts of the world for 4,000 years, but because it has not been understood completely, many people have remained skeptical,” said Nedergaard. “In this work, we provide information about one physical mechanism through which acupuncture reduces pain in the body.”

To do the experiment, the team performed acupuncture treatments on mice that had discomfort in one paw. The mice each received a 30-minute acupuncture treatment at a well known acupuncture point near the knee, with very fine needles rotated gently every five minutes, much as is done in standard acupuncture treatments with people.

The team made a number of observations regarding adenosine:

• In mice with normal functioning levels of adenosine, acupuncture reduced discomfort by two-thirds.

• In special “adenosine receptor knock-out mice” not equipped with the adenosine receptor, acupuncture had no effect.

• When adenosine was turned on in the tissues, discomfort was reduced even without acupuncture.

• During and immediately after an acupuncture treatment, the level of adenosine in the tissues near the needles was 24 times greater than before the treatment.

Adenosine Elimination Inhibitors May Boost Acupuncture’s Impact

Once they recognized adenosine’s role, the scientists explored the effects of a cancer drug called deoxycoformycin, which makes it harder for the tissue to remove adenosine. The compound boosted the effects of acupuncture treatment dramatically, nearly tripling the accumulation of adenosine in the muscles and more than tripling the length of time the treatment was effective.

“It’s clear that acupuncture may activate a number of different mechanisms,” said Josephine P. Briggs, MD, director of the National Center for Complementary and Alternative Medicine at the National Institutes of Health. “This carefully performed study identifies adenosine as a new player in the process. It’s an interesting contribution to our growing understanding of the complex intervention which is acupuncture.”

Funding for the work came from the New York State Spinal Cord Injury Program and the National Institutes of Health.
___
1. See article footnotes 4, 5, 6, and "Fibromyalgia imaging study demonstrates that Chinese acupuncture affects brain's ability to regulate pain - describes how."

Source: Based on University of Rochester (NY) Medical Center, news release, May 30, 2010




Post a Comment

Featured Products From the ProHealth Store
Energy NADH™ 5mg Ubiquinol CoQ-10 Corvalen M®

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments Post a Comment

Acupuncture no longer a placebo effect!
Posted by: KerryK
May 31, 2010
So, in the last couple of weeks the following important breakthroughs were reported: that IBS is a bacterial overgrowth - not psychological problem; that post traumatic stress syndrome is quickly curable with an injection to part of the nervous system and is therefore not psychological; and now acupuncture is firmly not a placebo effect. The prudent approach to the less understood illnesses seems is always to assume they are real and biological instead of psycho-social. What will be left for the psychologists???
Reply Reply

please read this review of the "adenosine" acupuncture study
Posted by: voner
Jun 4, 2010
if you're interested in this study, please read this review: http://bodyinmind.com.au/acupuncture-adenosine-and-cycling-fish/ the "body in mind" website is run by some extremely competent researchers in the field of pain.... also scroll down and read some of the comments..... timv
Reply Reply
 
Aching for Pain Relief?

Featured Products

Corvalen M® Corvalen M®
Restore & Maintain Your Body's Core Energy
Energy NADH™ 5mg Energy NADH™ 5mg
Long-lasting Energy, Without Stimulants
Ubiquinol CoQ-10 Ubiquinol CoQ-10
Reduced, Active Form of CoQ10
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium

Natural Remedies

Magnesium + Malic Acid: One-Two Punch for Pain & Fatigue Magnesium + Malic Acid: One-Two Punch for Pain & Fatigue
Front Line Defense Against Colds & Flu - Support for Healthy Immune System Balance Front Line Defense Against Colds & Flu - Support for Healthy Immune System Balance
Herbal Rescue for High Blood Sugar Herbal Rescue for High Blood Sugar
Clinically Studied Joint Relief Product for FM & ME/CFS Clinically Studied Joint Relief Product for FM & ME/CFS
Aches and Pains? A Simple Solution You'll Love Aches and Pains? A Simple Solution You'll Love

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler

· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE AND SAVE 15% NOW*
Be the first to know about new products, special discounts and the latest health news. *New subscribers only

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2016 ProHealth, Inc. All rights reserved. Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map