ProHealth health Vitamin and Natural Supplement Store and Health
Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help

|
|
|
|

Trending News

CDC Whistleblower Reveals Widespread Manipulation of Scientific Data and Top-Down Pressure on CDC Sc...

Do gut bacteria rule our minds?

Fatigue & Fibro Fog: Could You Have a B-12 Deficiency?

Irritable Bowel Syndrome: Unlocking the Secrets of Peppermint, Acacia and Fennel

9 Health Benefits of Cucumbers

Preserving Cognitive Function with Aging

Antibiotics in early life may alter immunity long-term

Coenzyme Q10 Benefits Symptoms in Gulf War Veterans: Results of a Randomized Double-Blind Study

Low vitamin D levels linked to increased risks after noncardiac surgery

Depression Linked to Parkinson's Disease

 
Print Page
Email Article

Autism ‘Metabolic Fingerprint’ Discovered - Diagnosis by Simple Urine Test Foreseen

  [ 36 votes ]   [ Discuss This Article ]
www.ProHealth.com • June 4, 2010


People with autism suffer from gastrointestinal disorders and have a different makeup of bacteria in their gut. Cause or consequence?

Children with autism have a different chemical fingerprint in their urine than non-autistic children, according to new research published June 4 by the Journal of Proteome Research.(1)

The researchers behind the study, from Imperial College London and the University of South Australia, suggest that their findings could ultimately lead to a simple urine test to determine whether or not a young child has autism.

• Autism affects an estimated 1 in every 100 people in the UK.

• People with autism have a range of different symptoms, but they commonly experience problems with communication and social skills, such as understanding other people's emotions and making conversation and eye contact.

• People with autism are also known to suffer from gastrointestinal disorders, and they have a different makeup of bacteria in their guts from non-autistic people.

This research shows that it is possible to distinguish between autistic and non-autistic children by looking at the by-products of gut bacteria and the body's metabolic processes in the children's urine.

The exact biological significance of gastrointestinal disorders in the development of autism is unknown.

The distinctive urinary metabolic fingerprint for autism identified in this study could form the basis of a non-invasive test that might help diagnose autism earlier.

This would enable autistic children to receive assistance, such as advanced behavioral therapy, earlier in their development than is currently possible.

At present, children are assessed for autism through a lengthy process involving a range of tests that explore the child's social interaction, communication and imaginative skills.

Early intervention can greatly improve the progress of children with autism but it is currently difficult to establish a firm diagnosis when children are under 18 months of age, although it is likely that changes may occur much earlier than this.

The researchers suggest that their new understanding of the makeup of bacteria in autistic children's guts could also help scientists to develop treatments to tackle autistic people's gastrointestinal problems.

Professor Jeremy Nicholson, the corresponding author of the study and head of Surgery and Cancer at Imperial College London, said:

• "Autism is a condition that affects a person's social skills, so at first it might seem strange that there's a relationship between autism and what's happening in someone's gut.

• “However, your metabolism and the makeup of your gut bacteria reflect all sorts of things, including your lifestyle and your genes.

• “Autism affects many different parts of a person's system, and our study shows that you can see how it disrupts their system by looking at their metabolism and their gut bacteria.

"We hope our findings might be the first step towards creating a simple urine test to diagnose autism at a really young age, although this is a long way off - such a test could take many years to develop and we're just beginning to explore the possibilities. We know that giving therapy to children with autism when they are very young can make a huge difference to their progress. A urine test might enable professionals to quickly identify children with autism and help them early on," he added.

The researchers are now keen to investigate whether metabolic differences in people with autism are related to the causes of the condition or are a consequence of its progression.

The researchers reached their conclusions by using H NMR Spectroscopy to analyze the urine of three groups of children aged between 3 and 9:

• 39 children who had previously been diagnosed with autism,

• 28 non-autistic siblings of children with autism, and

• 34 children who did not have autism and who did not have an autistic sibling.

They found that each of the three groups had a distinct chemical fingerprint.

• Non-autistic children with autistic siblings had a different chemical fingerprint than those without any autistic siblings,

• And autistic children had a different chemical fingerprint than the other two groups.

___
1. Article - “Urinary Metabolic phenotyping differentiates children with autism from their unaffected siblings and age-matched controls,” Ivan KS, Nicholson JK, et al.

Source: Journal of Proteome Research & Imperial College London, news release, Jun 3, 2010



Please Discuss This Article:   Post a Comment 



[ Be the first to comment on this article ]




 
Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Our FREE
Newsletter
Subscribe Now!
Receive up-to-date ME/CFS & Fibromyalgia treatment and research news
 Privacy Guaranteed  |  View Archives

Save on Vitamin B-12

Save on Vitamins and Supplements

Featured Products

Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
FibroSleep™ by ProHealth FibroSleep™ by ProHealth
The All-in-One Natural Sleep Aid
Optimized Curcumin Longvida® by ProHealth Optimized Curcumin Longvida® by ProHealth
Supports Cognition, Memory & Overall Health
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%

Natural Remedies

Protecting Our Eyes Against Time-Induced Damage Protecting Our Eyes Against Time-Induced Damage
The Remarkable Benefits of Reishi Medicinal Mushrooms The Remarkable Benefits of Reishi Medicinal Mushrooms
Could a B-12 Deficiency Be Causing Your Symptoms? Could a B-12 Deficiency Be Causing Your Symptoms?
How I Found My Long-Lost Energy How I Found My Long-Lost Energy
Magnesium + Malic Acid: One-Two Punch for Pain & Fatigue Magnesium + Malic Acid: One-Two Punch for Pain & Fatigue

FIBROMYALGIA RESOURCES
What is Fibromyalgia?
Fibromyalgia 101
Fibromyalgia Symptoms
Fibromyalgia Treatments
| CFS RESOURCES
What is CFS?
ME/CFS 101
ME/CFS Symptoms
ME/CFS Treatments
| FORUMS
Fibromyalgia
ME/CFS
ADVANCED MEDICAL LABS
WHOLESALE  |  AFFILIATES
GUARANTEE
CONTACT US
PRIVACY
RSS
SITE MAP
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing